Myrislignan - 98%, high purity , CAS No.171485-39-5

  • ≥98%
Item Number
M412873
Grouped product items
SKUSizeAvailabilityPrice Qty
M412873-1mg
1mg
In stock
$17.90
M412873-5mg
5mg
In stock
$74.90
M412873-25mg
25mg
In stock
$308.90
M412873-50mg
50mg
In stock
$513.90
M412873-100mg
100mg
Available within 1-2 weeks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$925.90

TNF-α Selective Inhibitors | Activators | Antagonists

Basic Description

SynonymsMyrislignan | 171485-39-5 | CHEMBL4085435 | (aR)-alpha-[(1S)-1-[2,6-Dimethoxy-4-(2-propen-1-yl)phenoxy]ethyl]-4-hydroxy-3-methoxybenzenemethanol | (-)-(1R,2S)-Myrislignan | DTXSID30333494 | HY-N0608 | BDBM50242967 | MFCD13195532 | s3261 | AKOS015909818 | AC-34668 | AS-77374 | CS-0
Specifications & Purity≥98%
Biochemical and Physiological MechanismsMyrislignan, a lignan isolated from Myristica fragrans Houtt, possesses anti-inflammatory activities. Myrislignan inhibits interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α). Myrislignan significantly inhibits the expressions of inducible NO syntha
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads
Note1mg卖完停产,不再备货
Product Description

Information

Myrislignan, a lignan isolated fromMyristica fragrans Houtt, possesses anti-inflammatory activities. Myrislignan inhibitsinterleukin-6 (IL-6)andtumour necrosis factor-α (TNF-α). Myrislignan significantly inhibits the expressions ofinducible NO synthase (iNOS)andcyclooxygenase-2 (COX-2)dose-dependently in LPS-stimulated macrophage cells. Myrislignan inhibits theNF-κBsignalling pathway activation.


Targets

IL-6 ; TNF-α ; iNOS ; COX-2 ; NF-κB

Product Properties

ALogP3.98
HBD Count2
Rotatable Bond9

Associated Targets(non-human)

Toxoplasma gondii (4585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
nanA Sialidase A (49 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Pubchem Sid488199898
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488199898
IUPAC Name 4-[(1R,2S)-2-(2,6-dimethoxy-4-prop-2-enylphenoxy)-1-hydroxypropyl]-2-methoxyphenol
INCHI InChI=1S/C21H26O6/c1-6-7-14-10-18(25-4)21(19(11-14)26-5)27-13(2)20(23)15-8-9-16(22)17(12-15)24-3/h6,8-13,20,22-23H,1,7H2,2-5H3/t13-,20-/m0/s1
InChi Key ULZFTGWWPHYLGI-RBZFPXEDSA-N
Canonical SMILES CC(C(C1=CC(=C(C=C1)O)OC)O)OC2=C(C=C(C=C2OC)CC=C)OC
Isomeric SMILES C[C@@H]([C@@H](C1=CC(=C(C=C1)O)OC)O)OC2=C(C=C(C=C2OC)CC=C)OC
PubChem CID 21636106
Molecular Weight 374.43

Certificates

Certificate of Analysis(COA)

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10 results found

Lot NumberCertificate TypeDateItem
D23141944Certificate of AnalysisMar 06, 2023 M412873
D23141954Certificate of AnalysisMar 06, 2023 M412873
D23141982Certificate of AnalysisMar 06, 2023 M412873
D23141983Certificate of AnalysisMar 06, 2023 M412873
D23141988Certificate of AnalysisMar 06, 2023 M412873
D23142013Certificate of AnalysisMar 06, 2023 M412873
D23142026Certificate of AnalysisMar 06, 2023 M412873
D23142029Certificate of AnalysisMar 06, 2023 M412873
D23142034Certificate of AnalysisMar 06, 2023 M412873
D23142122Certificate of AnalysisMar 06, 2023 M412873

Chemical and Physical Properties

SolubilitySolubility (25°C) In vitro DMSO: 100 mg/mL (267.07 mM);    
SensitivityLight sensitive
DMSO(mg / mL) Max Solubility100
DMSO(mM) Max Solubility267.072617044574
Water(mg / mL) Max Solubility-1

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