N-(2-{4-[2-oxo-2,3-dihydro-1H-benzo(d)imidazol-1-yl]piperidin-1-yl}ethyl)-2-naphthamide - >99%, high purity , CAS No.1130067-18-3

  • ≥99%
Item Number
N130532
Grouped product items
SKUSizeAvailabilityPrice Qty
N130532-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$241.90
N130532-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$604.90
N130532-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$753.90
N130532-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$945.90
N130532-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,136.90

Basic Description

Specifications & Purity≥99%
Biochemical and Physiological MechanismsVU0155056 or N-(2-{4-[2-oxo-2,3-dihydro-1H-benzo(d)imidazol-1-yl]piperidin-1-yl ethyl)-2-naphthamide is a cell permeable phospholipase D (PLD) inhibitor. It inhibits both PLD1 and PLD2
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

​VU0155056 has been used as a phospholipase D-1 (PLD1) inhibitor:
to study its role in regulated exocytosis;
to test bacterial and human PLD enzymes for specificity of inhibition;
in neuro-2a (N2a) cell culture and survival assay.

Associated Targets(Human)

PLD1 Tchem Phospholipase D1 (5 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PLD2 Tchem Phospholipase D2 (5 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PLD1 Tchem Phospholipase D1 (469 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PLD2 Tchem Phospholipase D2 (437 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]naphthalene-2-carboxamide
INCHI InChI=1S/C25H26N4O2/c30-24(20-10-9-18-5-1-2-6-19(18)17-20)26-13-16-28-14-11-21(12-15-28)29-23-8-4-3-7-22(23)27-25(29)31/h1-10,17,21H,11-16H2,(H,26,30)(H,27,31)
InChi Key IXLLRNNFUYEADZ-UHFFFAOYSA-N
Canonical SMILES C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCNC(=O)C4=CC5=CC=CC=C5C=C4
Isomeric SMILES C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCNC(=O)C4=CC5=CC=CC=C5C=C4
PubChem CID 25105704
Molecular Weight 414.50

Certificates

Certificate of Analysis(COA)

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9 results found

Lot NumberCertificate TypeDateItem
I2424660Certificate of AnalysisSep 03, 2024 N130532
I2424661Certificate of AnalysisSep 03, 2024 N130532
I2424662Certificate of AnalysisSep 03, 2024 N130532
I2424663Certificate of AnalysisSep 03, 2024 N130532
I2424665Certificate of AnalysisSep 03, 2024 N130532
I2424666Certificate of AnalysisSep 03, 2024 N130532
I2424667Certificate of AnalysisSep 03, 2024 N130532
I2424668Certificate of AnalysisSep 03, 2024 N130532
I2424669Certificate of AnalysisSep 03, 2024 N130532

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