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N-(2,5-Dioxopyrrolidin-3-yl)cinnamamide , CAS No.N609419, cereblon

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N-(2,5-Dioxopyrrolidin-3-yl)cinnamamide , CAS No.N609419, cereblon

Moligand™

PubChem CID: 139593560

Item Number

N609419

Grouped product items
SKU	Size	Availability	Price	Qty
N609419-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
N609419-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

cereblon

Basic Description

Specifications & Purity	Moligand™
Grade	Moligand™
Mechanism of action	cereblon

Associated Targets(Human)

CRBN Tclin Protein cereblon (0 Activities)

Discover Target: CRBN

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CSNK1A1 Tchem Cereblon/Casein kinase I alpha (35 Activities)

Discover Target: CSNK1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Cereblon isoform 4 (52 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	N-(2,5-Dioxopyrrolidin-3-yl)cinnamamide
INCHI	InChI=1S/C13H12N2O3/c16-11(7-6-9-4-2-1-3-5-9)14-10-8-12(17)15-13(10)18/h1-7,10H,8H2,(H,14,16)(H,15,17,18)/b7-6+
InChi Key	NSEUGMATEWSNTO-VOTSOKGWSA-N
Canonical SMILES	O=C(NC1CC(=O)NC1=O)/C=C/c1ccccc1
Isomeric SMILES	C1C(C(=O)NC1=O)NC(=O)/C=C/C2=CC=CC=C2
PubChem CID	139593560

Database links

PubChem CID	139593560

Certificates

Certificate of Analysis(COA)

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References

1. Heim C, Pliatsika D, Mousavizadeh F, Bär K, Hernandez Alvarez B, Giannis A, Hartmann MD. (2019) De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.. J Med Chem, 62 (14): (6615-6629). [PMID:31251063] [10.1021/op500134e]

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