AHL analog is a strong, broad-spectrum inhibitor of numerous LuxR-type receptors (e.g.: LuxR fromVibrio fischeri, LasR fromP. aeruginosa, and TraR fromAgrobacterium tumefaciens). This compound represents a good choice for initial testing of LuxR-type receptor inhibition.
Associated Targets(non-human)
luxRTranscriptional activator protein luxR (400 Activities)
1.Grant D Geske, Jennifer C O'Neill, David M Miller, Margrith E Mattmann, Helen E Blackwell. (2008-01-29) Comparative analyses of N-acylated homoserine lactones reveal unique structural features that dictate their ability to activate or inhibit quorum sensing.. Chembiochem : a European journal of chemical biology, 9 ((3)):( 389-400 ). [PMID:18224645]
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