N-[3-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-1-(4-methoxyphenyl)pyrazolo[3,4-b]pyridin-6-amine , CAS No.N608878, Inhibitor of aurora kinase B;Inhibitor of protein kinase A;Inhibitor of serine/threonine kinase 33
N-[3-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-1-(4-methoxyphenyl)pyrazolo[3,4-b]pyridin-6-amine , CAS No.N608878, Inhibitor of aurora kinase B;Inhibitor of protein kinase A;Inhibitor of serine/threonine kinase 33
1.Babij C, Zhang Y, Kurzeja RJ, Munzli A, Shehabeldin A, Fernando M, Quon K, Kassner PD, Ruefli-Brasse AA, Watson VJ et al.. (2011) STK33 kinase activity is nonessential in KRAS-dependent cancer cells.. Cancer Res, 71 (17):(5818-26). [PMID:21742770][10.1021/op500134e]
2.Weïwer M, Spoonamore J, Wei J, Guichard B, Ross NT, Masson K, Silkworth W, Dandapani S, Palmer M, Scherer CA et al.. (2012) A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells.. ACS Med Chem Lett, 3 (12):(1034-1038). [PMID:23256033][10.1021/op500134e]
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