N-[(4-bromophenyl)methyl]-2-{4-[(2-phenylethyl)sulfamoyl]phenoxy}acetamide , CAS No.N608860, Inhibitor of sphingomyelin synthase 1

Item Number

N608860

Grouped product items
SKU	Size	Availability	Price	Qty
N608860-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
N608860-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,001.90

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Synonyms

compound 1j

Specifications & Purity

Moligand™

Grade

Moligand™

Action Type

INHIBITOR

Mechanism of action

Inhibitor of sphingomyelin synthase 1

Associated Targets(Human)

SGMS1 Tchem Phosphatidylcholine:ceramide cholinephosphotransferase 1 (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SGMS1 Tchem Phosphatidylcholine:ceramide cholinephosphotransferase 1 (149 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	N-[(4-bromophenyl)methyl]-2-{4-[(2-phenylethyl)sulfamoyl]phenoxy}acetamide
INCHI	InChI=1S/C23H23BrN2O4S/c24-20-8-6-19(7-9-20)16-25-23(27)17-30-21-10-12-22(13-11-21)31(28,29)26-15-14-18-4-2-1-3-5-18/h1-13,26H,14-17H2,(H,25,27)
InChi Key	CZAFIFBJBFDMTP-UHFFFAOYSA-N
Canonical SMILES	O=C(NCc1ccc(cc1)Br)COc1ccc(cc1)S(=O)(=O)NCCc1ccccc1
Isomeric SMILES	C1=CC=C(C=C1)CCNS(=O)(=O)C2=CC=C(C=C2)OCC(=O)NCC3=CC=C(C=C3)Br
PubChem CID	91938094

References

1. Li YL, Qi XY, Jiang H, Deng XD, Dong YP, Ding TB, Zhou L, Men P, Chu Y, Wang RX et al.. (2015) Discovery, synthesis and biological evaluation of 2-(4-(N-phenethylsulfamoyl)phenoxy)acetamides (SAPAs) as novel sphingomyelin synthase 1 inhibitors.. Bioorg Med Chem, 23 (18): (6173-84). [PMID:26314925]

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Basic Description