Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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N608846-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,334.90 | |
N608846-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,000.90 |
Specifications & Purity | Moligand™ |
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Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of casein kinase 2; alpha 1 polypeptide subunit;Inhibitor of dual specificity tyrosine phosphorylation regulated kinase 3;Inhibitor of homeodomain interacting protein kinase 2;Inhibitor of Pim-3 proto-oncogene; serine/threonine kinase |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methylphenyl]acetamide |
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INCHI | InChI=1S/C19H19N7O/c1-11-3-4-15(7-16(11)22-12(2)27)23-17-8-18(24-14-5-6-14)26-19(25-17)13(9-20)10-21-26/h3-4,7-8,10,14,24H,5-6H2,1-2H3,(H,22,27)(H,23,25) |
InChi Key | GDSQVLMYYCNAGP-UHFFFAOYSA-N |
Canonical SMILES | N#Cc1cnn2c1nc(Nc1ccc(c(c1)NC(=O)C)C)cc2NC1CC1 |
Isomeric SMILES | CC1=C(C=C(C=C1)NC2=NC3=C(C=NN3C(=C2)NC4CC4)C#N)NC(=O)C |
PubChem CID | 72163809 |
PubChem CID | 72163809 |
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BindingDB Ligand | 50437434 |
ChEMBL Ligand | CHEMBL2409175 |
RCSB PDB Ligand | 5Y2 |
Enter Lot Number to search for COA:
1. Dowling JE, Alimzhanov M, Bao L, Block MH, Chuaqui C, Cooke EL, Denz CR, Hird A, Huang S, Larsen NA et al.. (2013) Structure and Property Based Design of Pyrazolo[1,5-a]pyrimidine Inhibitors of CK2 Kinase with Activity in Vivo.. ACS Med Chem Lett, 4 (8): (800-5). [PMID:24900749] [10.1021/op500134e] |