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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A105211-25g | 25g | In stock | $17.90 | |
A105211-100g | 100g | In stock | $49.90 | |
A105211-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $179.90 |
Synonyms | 2-Acetamido-2-deoxy-D-glucose 2-Acetamido-2-deoxy-D-glucopyranose N-Acetyl-D-glucosamine N-[2,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl]acetamide D-GlcNAc |
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Specifications & Purity | ≥98% |
Storage Temp | Store at -20°C,Argon charged |
Shipped In | Ice chest + Ice pads |
Product Description | N-Acetyl-D-glucosamine (D-GlcNAc) is a derivitized glucose monomer found in polymers of bacterial cell walls, chitin, hyaluronic acids and various glycans. D-GlcNAc is used to identify, differentiate and characterize N-acetyl-β-D-hexoaminidase(s). |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Pubchem Sid | 488191997 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488191997 |
Canonical SMILES | CC(=O)N[C@@H](C=O)[C@H]([C@@H]([C@@H](CO)O)O)O |
Isomeric SMILES | CC(=O)N[C@@H](C=O)[C@H]([C@@H]([C@@H](CO)O)O)O |
WGK Germany | 3 |
PubChem CID | 1738118 |
Molecular Weight | 221.21 |
Beilstein | 1727589 |
Reaxy-Rn | 1913592 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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F2417098 | Certificate of Analysis | Jun 22, 2024 | A105211 |
E2308207 | Certificate of Analysis | Apr 10, 2023 | A105211 |
E2308208 | Certificate of Analysis | Apr 10, 2023 | A105211 |
E2308209 | Certificate of Analysis | Apr 10, 2023 | A105211 |
E2308211 | Certificate of Analysis | Apr 10, 2023 | A105211 |
C2328195 | Certificate of Analysis | Mar 30, 2023 | A105211 |
B2322245 | Certificate of Analysis | Mar 01, 2023 | A105211 |
B2322247 | Certificate of Analysis | Mar 01, 2023 | A105211 |
H2204255 | Certificate of Analysis | Jul 23, 2022 | A105211 |
H2204257 | Certificate of Analysis | Jul 23, 2022 | A105211 |
H2204264 | Certificate of Analysis | Jul 23, 2022 | A105211 |
H2204265 | Certificate of Analysis | Jul 23, 2022 | A105211 |
Solubility | Solubility in Water almost transparency |
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Sensitivity | Moisture sensitive |
Specific Rotation[α] | +39.0 to +43.0 deg(C=1, H2O) |
Melt Point(°C) | 211°C |
WGK Germany | 3 |
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Reaxy-Rn | 1913592 |
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1. A Cassone,P A Sullivan,M G Shepherd. (1985-01-01) N-acetyl-D-glucosamine-induced morphogenesis in Candida albicans.. Microbiologica, 8 ((1)): (85-99). [PMID:3883103] |
2. A Breborowicz,K Wieczorowska-Tobis,M Kuzlan,J Kupsz,K Korybalska,A Polubinska,P Krzysztof,I French,P Tam,G Wu. (1997-01-01) N-acetylglucosamine: a new osmotic solute in peritoneal dialysis solutions.. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 17 Suppl 2 (S80-S83). [PMID:9163804] |
3. T Y Chou,G W Hart. (2003-10-10) O-linked N-acetylglucosamine and cancer: messages from the glycosylation of c-Myc.. Advances in experimental medicine and biology, 491 (413-418). [PMID:14533811] |
4. Gerald W Hart,Michael P Housley,Chad Slawson. (2007-04-27) Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins.. Nature, 446 ((7139)): (1017-1022). [PMID:17460662] |
5. Gladys A Ngoh,Steven P Jones. (2008-09-05) New insights into metabolic signaling and cell survival: the role of beta-O-linkage of N-acetylglucosamine.. The Journal of pharmacology and experimental therapeutics, 327 ((3)): (602-609). [PMID:18768779] |
6. Alina Kepka,Sławomir D Szajda,Anna Jankowska,Napoleon Waszkiewicz,Sylwia Chojnowska,Krzysztof Zwierz. (2008-12-31) [N-acetyl-beta-hexosaminidase--marker of damage to renal proximal tubules].. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 25 ((147)): (288-290). [PMID:19112852] |
7. John C Chatham,Richard B Marchase. (2009-07-18) The role of protein O-linked beta-N-acetylglucosamine in mediating cardiac stress responses.. Biochimica et biophysica acta, 1800 ((2)): (57-66). [PMID:19607882] |
8. Chutikarn Butkinaree,Kyoungsook Park,Gerald W Hart. (2009-08-04) O-linked beta-N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress.. Biochimica et biophysica acta, 1800 ((2)): (96-106). [PMID:19647786] |
9. Jeen-Kuan Chen,Chia-Rui Shen,Chao-Lin Liu. (2010-10-16) N-acetylglucosamine: production and applications.. Marine drugs, 8 ((9)): (2493-2516). [PMID:20948902] |
10. Victor M Darley-Usmar,Lauren E Ball,John C Chatham. (2011-09-01) Protein O-linked β-N-acetylglucosamine: a novel effector of cardiomyocyte metabolism and function.. Journal of molecular and cellular cardiology, 52 ((3)): (538-549). [PMID:21878340] |
11. Natasha E Zachara. (2012-01-31) The roles of O-linked β-N-acetylglucosamine in cardiovascular physiology and disease.. American journal of physiology. Heart and circulatory physiology, 302 ((10)): (H1905-H1918). [PMID:22287582] |
12. Bingwu Yu,Hugo van Ingen,Darón I Freedberg. (2013-01-09) Constant time INEPT CT-HSQC (CTi-CT-HSQC) - A new NMR method to measure accurate one-bond J and RDCs with strong 1H-1H couplings in natural abundance.. Journal of magnetic resonance (San Diego, Calif. : 1997), 228 (159-165). [PMID:23294631] |
13. Zhi Yuan Ma,Yuliya Skorobogatko,Keith Vosseller. (2013-01-09) Tandem lectin weak affinity chromatography for glycoprotein enrichment.. Methods in molecular biology (Clifton, N.J.), 951 (21-31). [PMID:23296521] |
14. Peng Zhao,Stephanie H Stalnaker,Lance Wells. (2013-01-09) Approaches for site mapping and quantification of O-linked glycopeptides.. Methods in molecular biology (Clifton, N.J.), 951 (229-244). [PMID:23296534] |
15. Kirsi Rilla,Sanna Oikari,Tiina A Jokela,Juha M T Hyttinen,Riikka Kärnä,Raija H Tammi,Markku I Tammi. (2013-01-11) Hyaluronan synthase 1 (HAS1) requires higher cellular UDP-GlcNAc concentration than HAS2 and HAS3.. The Journal of biological chemistry, 288 ((8)): (5973-5983). [PMID:23303191] |
16. David D L Minh,Lee Makowski. (2013-02-28) Wide-angle X-ray solution scattering for protein-ligand binding: multivariate curve resolution with Bayesian confidence intervals.. Biophysical journal, 104 ((4)): (873-883). [PMID:23442966] |
17. Lucy G Weaver,Yogendra Singh,Joanne T Blanchfield,Paul L Burn. (2013-03-26) A simple iterative method for the synthesis of β-(1→6)-glucosamine oligosaccharides.. Carbohydrate research, 371 (68-76). [PMID:23523915] |
18. Feng-zhen Jin,Chao Yu,De-zhang Zhao,Ming-jun Wu,Zhu Yang. (2013-03-26) A correlation between altered O-GlcNAcylation, migration and with changes in E-cadherin levels in ovarian cancer cells.. Experimental cell research, 319 ((10)): (1482-1490). [PMID:23524144] |
19. Shigeyuki Tsutsui,Toru Ariji,Akira Sato,Takaya Yoshida,Nozomi Yamamura,Tomoyuki Odaka,Kyosuke Araki,Hiroaki Suetake,Toshiaki Miyadai,Osamu Nakamura. (2013-04-09) Serum GlcNAc-binding IgM of fugu (Takifugu rubripes) suppresses the growth of fish pathogenic bacteria: a novel function of teleost antibody.. Developmental and comparative immunology, 41 ((1)): (20-26). [PMID:23562572] |
20. Sun-Jung Kim,Hirohiko Ise,Eunju Kim,Mistuaki Goto,Toshihiro Akaike,Bong Hyun Chung. (2013-06-04) Imaging and therapy of liver fibrosis using bioreducible polyethylenimine/siRNA complexes conjugated with N-acetylglucosamine as a targeting moiety.. Biomaterials, 34 ((27)): (6504-6514). [PMID:23726228] |
21. Yi Qian,Heather Flanagan-Steet,Eline van Meel,Richard Steet,Stuart A Kornfeld. (2013-06-05) The DMAP interaction domain of UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase is a substrate recognition module.. Proceedings of the National Academy of Sciences of the United States of America, 110 ((25)): (10246-10251). [PMID:23733939] |
22. Mario R de O Barsottini,Juliana F de Oliveira,Douglas Adamoski,Paulo J P L Teixeira,Paula F V do Prado,Henrique O Tiezzi,Mauricio L Sforça,Alexandre Cassago,Rodrigo V Portugal,Paulo S L de Oliveira,Ana C de M Zeri,Sandra M G Dias,Gonçalo A G Pereira,Andre L B Ambrosio. (2013-08-02) Functional diversification of cerato-platanins in Moniliophthora perniciosa as seen by differential expression and protein function specialization.. Molecular plant-microbe interactions : MPMI, 26 ((11)): (1281-1293). [PMID:23902259] |
23. Ee Phie Tan,Sarah Caro,Anish Potnis,Christopher Lanza,Chad Slawson. (2013-08-16) O-linked N-acetylglucosamine cycling regulates mitotic spindle organization.. The Journal of biological chemistry, 288 ((38)): (27085-27099). [PMID:23946484] |
24. Brian A Lewis. (2013-10-01) O-GlcNAcylation at promoters, nutrient sensors, and transcriptional regulation.. Biochimica et biophysica acta, 1829 ((11)): (1202-1206). [PMID:24076017] |
25. Xun Huang,Qiuming Pan,Danni Sun,Wei Chen,Aijun Shen,Min Huang,Jian Ding,Meiyu Geng. (2013-11-12) O-GlcNAcylation of cofilin promotes breast cancer cell invasion.. The Journal of biological chemistry, 288 ((51)): (36418-36425). [PMID:24214978] |
26. Yasuhito Onodera,Jin-Min Nam,Mina J Bissell. (2013-12-10) Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways.. The Journal of clinical investigation, 124 ((1)): (367-384). [PMID:24316969] |
27. John W Bullen,Jeremy L Balsbaugh,Dipanjan Chanda,Jeffrey Shabanowitz,Donald F Hunt,Dietbert Neumann,Gerald W Hart. (2014-02-25) Cross-talk between two essential nutrient-sensitive enzymes: O-GlcNAc transferase (OGT) and AMP-activated protein kinase (AMPK).. The Journal of biological chemistry, 289 ((15)): (10592-10606). [PMID:24563466] |
28. Yuko Tashima,Pamela Stanley. (2014-02-28) Antibodies that detect O-linked β-D-N-acetylglucosamine on the extracellular domain of cell surface glycoproteins.. The Journal of biological chemistry, 289 ((16)): (11132-11142). [PMID:24573683] |
29. J Richter,K Capková,V Hříbalová,L Vannucci,I Danyi,M Malý,A Fišerová. (2014-03-05) Collagen-induced arthritis: severity and immune response attenuation using multivalent N-acetyl glucosamine.. Clinical and experimental immunology, 177 ((1)): (121-133). [PMID:24588081] |
30. . (2014-03-14) Distinct usage of three C-type lectins by Japanese encephalitis virus: DC-SIGN, DC-SIGNR, and LSECtin.. Archives of virology, 159 ((8)): (2023-2031). [PMID:24623090] |
31. Lili Zhang,Marianne Gallup,Lorna Zlock,Yu Ting Feeling Chen,Walter E Finkbeiner,Nancy A McNamara. (2014-05-20) Pivotal role of MUC1 glycosylation by cigarette smoke in modulating disruption of airway adherens junctions in vitro.. The Journal of pathology, 234 ((1)): (60-73). [PMID:24838315] |
32. Radka Svobodová Vařeková,Deepti Jaiswal,David Sehnal,Crina-Maria Ionescu,Stanislav Geidl,Lukáš Pravda,Vladimír Horský,Michaela Wimmerová,Jaroslav Koča. (2014-05-23) MotiveValidator: interactive web-based validation of ligand and residue structure in biomolecular complexes.. Nucleic acids research, 42 ((Web Server issue)): (W227-W233). [PMID:24848013] |
33. Zachary D Moye,Robert A Burne,Lin Zeng. (2014-06-15) Uptake and metabolism of N-acetylglucosamine and glucosamine by Streptococcus mutans.. Applied and environmental microbiology, 80 ((16)): (5053-5067). [PMID:24928869] |
34. Shannon M Bailey,Uduak S Udoh,Martin E Young. (2014-06-15) Circadian regulation of metabolism.. The Journal of endocrinology, 222 ((2)): (R75-R96). [PMID:24928941] |
35. Jana Held,Tamirat Gebru,Markus Kalesse,Rolf Jansen,Klaus Gerth,Rolf Müller,Benjamin Mordmüller. (2014-08-13) Antimalarial activity of the myxobacterial macrolide chlorotonil a.. Antimicrobial agents and chemotherapy, 58 ((11)): (6378-6384). [PMID:25114138] |
36. Karel Horňák,Jakob Pernthaler. (2014-09-23) A novel ion-exclusion chromatography-mass spectrometry method to measure concentrations and cycling rates of carbohydrates and amino sugars in freshwaters.. Journal of chromatography. A, 1365 (115-123). [PMID:25242224] |
37. Susan A Marsh,Helen E Collins,John C Chatham. (2014-10-23) Protein O-GlcNAcylation and cardiovascular (patho)physiology.. The Journal of biological chemistry, 289 ((50)): (34449-34456). [PMID:25336635] |
38. Brian A Lewis,John A Hanover. (2014-10-23) O-GlcNAc and the epigenetic regulation of gene expression.. The Journal of biological chemistry, 289 ((50)): (34440-34448). [PMID:25336654] |
39. Md Arifur Rahman,Yun Hee Choi,G C Pradeep,Jin Cheol Yoo. (2014-11-02) An ammonium sulfate sensitive chitinase from Streptomyces sp. CS501.. Archives of pharmacal research, 37 ((12)): (1522-1529). [PMID:25359199] |
40. Emma L Humphrey,Erica Lacey,Lam T Le,Lucy Feng,Francesca Sciandra,Charlotte R Morris,Jane E Hewitt,Ian Holt,Andrea Brancaccio,Rita Barresi,Caroline A Sewry,Susan C Brown,Glenn E Morris. (2014-11-13) A new monoclonal antibody DAG-6F4 against human alpha-dystroglycan reveals reduced core protein in some, but not all, dystroglycanopathy patients.. Neuromuscular disorders : NMD, 25 ((1)): (32-42). [PMID:25387694] |
41. Tian Liu,Meng Xia,Haitao Zhang,Hao Zhou,Jing Wang,Xu Shen,Qing Yang. (2014-12-02) Exploring NAG-thiazoline and its derivatives as inhibitors of chitinolytic β-acetylglucosaminidases.. FEBS letters, 589 ((1)): (110-116). [PMID:25436416] |
42. Vasile I Pavlov,Ying S Tan,Erin E McClure,Laura R La Bonte,Chenhui Zou,William B Gorsuch,Gregory L Stahl. (2014-12-09) Human mannose-binding lectin inhibitor prevents myocardial injury and arterial thrombogenesis in a novel animal model.. The American journal of pathology, 185 ((2)): (347-355). [PMID:25482922] |
43. C Peter Verrijzer. (2014-12-10) Sugarcoating Polycomb repression.. Developmental cell, 31 ((5)): (521-522). [PMID:25490262] |
44. Syoichiro Kono,Tomoko Kurata,Kota Sato,Yoshio Omote,Nozomi Hishikawa,Toru Yamashita,Kentaro Deguchi,Koji Abe. (2014-12-24) Neurovascular protection by telmisartan via reducing neuroinflammation in stroke-resistant spontaneously hypertensive rat brain after ischemic stroke.. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 24 ((3)): (537-547). [PMID:25534368] |
45. Patricia Bonin,Christophe Vieira,Régis Grimaud,Cécile Militon,Philippe Cuny,Oscar Lima,Sophie Guasco,Corina P D Brussaard,Valérie Michotey. (2015-01-07) Substrates specialization in lipid compounds and hydrocarbons of Marinobacter genus.. Environmental science and pollution research international, 22 ((20)): (15347-15359). [PMID:25561256] |
46. Hong-Fei Wang,Yong-Guang Zhang,Li Li,Wei-Hong Liu,Wael N Hozzein,Ji-Yue Chen,Jian-Wei Guo,Yuan-Ming Zhang,Wen-Jun Li. (2015-01-09) Okibacterium endophyticum sp. nov., a novel endophytic actinobacterium isolated from roots of Salsola affinis C. A. Mey.. Antonie van Leeuwenhoek, 107 ((3)): (835-843). [PMID:25566956] |
47. Shamoon Naseem,Esteban Araya,James B Konopka. (2015-01-23) Hyphal growth in Candida albicans does not require induction of hyphal-specific gene expression.. Molecular biology of the cell, 26 ((6)): (1174-1187). [PMID:25609092] |
48. Sercan Karav,Juliana Maria Leite Nobrega De Moura Bell,Annabelle Le Parc,Yan Liu,David A Mills,David E Block,Daniela Barile. (2015-06-23) Characterizing the release of bioactive N-glycans from dairy products by a novel endo-β-N-acetylglucosaminidase.. Biotechnology progress, 31 ((5)): (1331-1339). [PMID:26097235] |
49. Jiqing Huang,Juergen Kast. (2015-07-15) Quantitative Glycoproteomic Analysis Identifies Platelet-Induced Increase of Monocyte Adhesion via the Up-Regulation of Very Late Antigen 5.. Journal of proteome research, 14 ((8)): (3015-3026). [PMID:26159767] |
50. Thomas Jank,Stephanie Eckerle,Marcus Steinemann,Christoph Trillhaase,Marianne Schimpl,Sebastian Wiese,Daan M F van Aalten,Wolfgang Driever,Klaus Aktories. (2015-07-21) Tyrosine glycosylation of Rho by Yersinia toxin impairs blastomere cell behaviour in zebrafish embryos.. Nature communications, 6 (7807-7807). [PMID:26190758] |
51. Changhoon Ha,Kihong Lim. (2015-10-04) O-GlcNAc modification of Sp3 and Sp4 transcription factors negatively regulates their transcriptional activities.. Biochemical and biophysical research communications, 467 ((2)): (341-347). [PMID:26431879] |
52. Valeria de Turris,Raffaela Teloni,Paola Chiani,Carla Bromuro,Sabrina Mariotti,Manuela Pardini,Roberto Nisini,Antonella Torosantucci,Maria Cristina Gagliardi. (2015-11-13) Candida albicans Targets a Lipid Raft/Dectin-1 Platform to Enter Human Monocytes and Induce Antigen Specific T Cell Responses.. PloS one, 10 ((11)): (e0142531-e0142531). [PMID:26562838] |
53. M Kopec,A Imiela,H Abramczyk. (2019-01-19) Monitoring glycosylation metabolism in brain and breast cancer by Raman imaging.. Scientific reports, 9 ((1)): (166-166). [PMID:30655566] |
54. Natasia Paukovich,Jasmina S Redzic,Ying-Chih Chi,Jeremy T Rahkola,Aaron Issaian,Ashley Blue,Kirk C Hansen,Edward N Janoff,Elan Z Eisenmesser. (2019-08-08) Streptococcus pneumoniae G5 domains bind different ligands.. Protein science : a publication of the Protein Society, 28 ((10)): (1797-1805). [PMID:31390088] |
55. Krzysztof Nowacki,Izabela Stępniak,Enrico Langer,Mikhail Tsurkan,Marcin Wysokowski,Iaroslav Petrenko,Yuliya Khrunyk,Andriy Fursov,Marzia Bo,Giorgio Bavestrello,Yvonne Joseph,Hermann Ehrlich. (2020-06-06) Electrochemical Approach for Isolation of Chitin from the Skeleton of the Black Coral Cirrhipathes sp. (Antipatharia).. Marine drugs, 18 ((6)): [PMID:32498448] |
56. Prawit Oangkhana,Piti Amparyup,Anchalee Tassanakajon,Elumalai Preetham,Ratree Wongpanya. (2020-12-29) Characterization and functional analysis of fibrinogen-related protein (FreP) in the black tiger shrimp, Penaeus monodon.. Fish & shellfish immunology, 109 (87-96). [PMID:33359206] |
57. Karsten Arends,Ertugrul-Kaan Celik,Ines Probst,Nikolaus Goessweiner-Mohr,Christian Fercher,Lukas Grumet,Cem Soellue,Mohammad Yaser Abajy,Tuerkan Sakinc,Melanie Broszat,Katarzyna Schiwon,Guenther Koraimann,Walter Keller,Elisabeth Grohmann. (2013-08-06) TraG encoded by the pIP501 type IV secretion system is a two-domain peptidoglycan-degrading enzyme essential for conjugative transfer.. Journal of bacteriology, 195 ((19)): (4436-4444). [PMID:23913323] |
58. Maria Cristina Gambetta,Jürg Müller. (2014-12-04) O-GlcNAcylation prevents aggregation of the Polycomb group repressor polyhomeotic.. Developmental cell, 31 ((5)): (629-639). [PMID:25468754] |
59. Janette Reader,Mariëtte Botha,Anjo Theron,Sonja B Lauterbach,Claire Rossouw,Dewaldt Engelbrecht,Melanie Wepener,Annél Smit,Didier Leroy,Dalu Mancama,Theresa L Coetzer,Lyn-Marie Birkholtz. (2015-05-23) Nowhere to hide: interrogating different metabolic parameters of Plasmodium falciparum gametocytes in a transmission blocking drug discovery pipeline towards malaria elimination.. Malaria journal, 14 (213-213). [PMID:25994518] |