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N-Acetyl-L-Cysteine - 99%, high purity , Mycolytic, CAS No.616-91-1, Mycolytic

  • Moligand™
  • ≥99%
Item Number
A105420
Grouped product items
SKUSizeAvailabilityPrice Qty
A105420-10g
10g
In stock
$24.90
A105420-25g
25g
In stock
$56.90
A105420-100g
100g
In stock
$150.90
A105420-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$532.90

Basic Description

SynonymsN-Acetyl-L-cysteine|acetylcysteine|616-91-1|N-Acetylcysteine|mercapturic acid|Acetadote|L-Acetylcysteine|Broncholysin|Mucomyst|Fluimucetin|N-Acetyl-cysteine|Fluimucil|Parvolex|Respaire|Acetein|Flumucetin|Fluprowit|Airbron|Brunac|Fabrol|Mucosil|L-Cysteine,
Specifications & Purity99%
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
GradeMoligand™
Mechanism of actionMycolytic
Product Description

N-Acetyl-L-cysteine is an acetylated amino acid with antioxidant and mucolytic properties. These two activities have made N-Acetyl-L-cysteine particularly relevant in cystic fibrosis studies, where the antioxidant/reducing character of the compound is described to ameliorate the characteristic systemic redox imbalance state of cystic fibrosis and the mucolytic properties of the compound are shown to impede upon the congestion and inflammation correlated to this redox state. As a mucolytic, N-Acetyl-L-cysteine serves to dissipate disulfide bonds across mucoproteins, loosening and clearing the viscosity of sputum. N-Acetyl-L-cysteine shows complimentary action to glutathione, both demonstrating antioxidant activity throμgh their thiol functionality, and both are shown to protect against peroxidative stress related to septic shock. N-Acetyl-L-cysteine has also been shown to induce apoptosis in vascular smooth muscle cells, indicating that these cells respond differently to changes in reduction-oxidation state than other tissues that are normally protected by the presence of antioxidants. This observation in vascular smooth muscle cells indicates N-Acetyl-L-cysteine as an interventional tool upon arteriosclerotic proliferation of these cells.An antioxidant mucolytic acetylated amino acid.

Product Properties

ALogP0.4

Names and Identifiers

Pubchem Sid488181517
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488181517
IUPAC Name (2R)-2-acetamido-3-sulfanylpropanoic acid
INCHI InChI=1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
InChi Key PWKSKIMOESPYIA-BYPYZUCNSA-N
Canonical SMILES CC(=O)N[C@@H](CS)C(O)=O
Isomeric SMILES CC(=O)N[C@@H](CS)C(=O)O
WGK Germany 2
RTECS HA1660000
PubChem CID 12035
Molecular Weight 163.19
Beilstein 1724426

Certificates

Certificate of Analysis(COA)

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23 results found

Lot NumberCertificate TypeDateItem
F2421091Certificate of AnalysisJun 05, 2024 A105420
F2421092Certificate of AnalysisJun 05, 2024 A105420
F2421093Certificate of AnalysisJun 05, 2024 A105420
K2329356Certificate of AnalysisNov 17, 2023 A105420
K2329355Certificate of AnalysisNov 17, 2023 A105420
K2329354Certificate of AnalysisNov 17, 2023 A105420
K2329351Certificate of AnalysisNov 17, 2023 A105420
K2329352Certificate of AnalysisNov 17, 2023 A105420
K2329353Certificate of AnalysisNov 17, 2023 A105420
K2320006Certificate of AnalysisNov 09, 2023 A105420
B2308430Certificate of AnalysisFeb 11, 2023 A105420
G2303587Certificate of AnalysisOct 25, 2022 A105420
L2207095Certificate of AnalysisOct 25, 2022 A105420
L2207093Certificate of AnalysisOct 25, 2022 A105420
L2207032Certificate of AnalysisOct 25, 2022 A105420
L2207031Certificate of AnalysisOct 25, 2022 A105420
C2325027Certificate of AnalysisOct 25, 2022 A105420
B2419115Certificate of AnalysisOct 25, 2022 A105420
B2218166Certificate of AnalysisDec 23, 2021 A105420
B2322267Certificate of AnalysisDec 23, 2021 A105420
B2322263Certificate of AnalysisDec 23, 2021 A105420
B2218184Certificate of AnalysisDec 23, 2021 A105420
B2218167Certificate of AnalysisDec 23, 2021 A105420

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Chemical and Physical Properties

SolubilitySoluble in water (100 mg/ml) with heating and obtained a clear, colorless solution, 1 in 2 of ethanol, DMSO (≥33 mg/ml) at 25 °C, hot isopropyl alcohol, methyl acetate, ethyl acetate and methanol. Practically insoluble in chloroform, and ether.
SensitivityAir sensitive
Specific Rotation[α]24 ° (JPC Method)
Melt Point(°C)109-111°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H319:Causes serious eye irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 2
RTECS HA1660000
Merck Index 88

Related Documents

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