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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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N336049-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $88.90 | |
N336049-250mg | 250mg | In stock | $200.90 | |
N336049-1g | 1g | In stock | $720.90 |
a diffusable quorum sensing lactone
Synonyms | N-(butyryl)-L-homoserine lactone | C4-HSL | SR-01000946805 | C4-HSL;N-Butyryl-L-homoserine lactone | N-[(3s)-2-Oxotetrahydrofuran-3-Yl]butanamide | PAI-1-2 | DTXSID30435962 | SB84058 | CS-0064384 | SY038520 | N-[(3S)-TETRAHYDRO-2-OXO-3-FURANYL]BUTANAMIDE |
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Specifications & Purity | ≥98% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | N-butyryl-L-Homoserine lactone, quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-butyryl-L-Homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this molecule include regulation of virulence in general, infection prevention, and formation of biofilms. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | N-[(3S)-2-oxooxolan-3-yl]butanamide |
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INCHI | InChI=1S/C8H13NO3/c1-2-3-7(10)9-6-4-5-12-8(6)11/h6H,2-5H2,1H3,(H,9,10)/t6-/m0/s1 |
InChi Key | VFFNZZXXTGXBOG-LURJTMIESA-N |
Canonical SMILES | CCCC(=O)NC1CCOC1=O |
Isomeric SMILES | CCCC(=O)N[C@H]1CCOC1=O |
PubChem CID | 10130163 |
Molecular Weight | 171.19 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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A2410037 | Certificate of Analysis | Jun 19, 2022 | N336049 |
G2227302 | Certificate of Analysis | Jun 19, 2022 | N336049 |
G2227374 | Certificate of Analysis | Jun 19, 2022 | N336049 |
G2227376 | Certificate of Analysis | Jun 19, 2022 | N336049 |
J2317061 | Certificate of Analysis | Jun 19, 2022 | N336049 |
Solubility | Soluble in water (10 mg/ml at 25° C), ethanol, DMSO (~30 mg/ml), DMF (~30 mg/ml), and PBS(pH 7.2) (~10 mg/ml). |
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Refractive Index | n20D1.48 |
Boil Point(°C) | 428.06° C at 760 mmHg |
Melt Point(°C) | 119.53° C (Predicted) |
1. Liushen Lu, Junwei Wang, Ting Qin, Kai Chen, Jun Xie, Bingwen Xi. (2023) Carvacrol Inhibits Quorum Sensing in Opportunistic Bacterium Aeromonas hydrophila. Microorganisms, 11 (8): (2027). [PMID:37630587] [10.3390/microorganisms11082027] |
1. Liushen Lu, Junwei Wang, Ting Qin, Kai Chen, Jun Xie, Bingwen Xi. (2023) Carvacrol Inhibits Quorum Sensing in Opportunistic Bacterium Aeromonas hydrophila. Microorganisms, 11 (8): (2027). [PMID:37630587] [10.3390/microorganisms11082027] |