N⁶-Cyclopentyladenosine - 98%, high purity , CAS No.41552-82-3, Agonist of A 1 receptor;Agonist of A 2A receptor;Agonist of A 2B receptor;Agonist of A 3 receptor
N⁶-Cyclopentyladenosine - 98%, high purity , CAS No.41552-82-3, Agonist of A 1 receptor;Agonist of A 2A receptor;Agonist of A 2B receptor;Agonist of A 3 receptor
Potent and selective adenosine A 1 receptor agonist (K i values are 2.3, 790 and 43 nM for human A 1 , A 2A and A 3 receptors, respectively). Centrally active following systemic administration in vivo . Anticonvulsant, with cardiovacular actions, and effe
Storage Temp
Store at -20°C
Shipped In
Ice chest + Ice pads
Grade
Moligand™
Action Type
AGONIST
Mechanism of action
Agonist of A 1 receptor;Agonist of A 2A receptor;Agonist of A 2B receptor;Agonist of A 3 receptor
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
1.Ster J et al.. (2011) Enhancement of CA3 hippocampal network activity by activation of group II metabotropic glutamate receptors.. Proc Natl Acad Sci U S A, 108 (24):(9993-7). [PMID:21628565]
2.Chiang PH et al.. (2012) GABA is depolarizing in hippocampal dentate granule cells of the adolescent and adult rats.. J Neurosci, 32 (62-7). [PMID:22219270]
4.Schätzle P et al.. (2011) Rapid and reversible formation of spine head filopodia in response to muscarinic receptor activation in CA1 pyramidal cells.. J Physiol, 589 (Pt 17):(4353-64). [PMID:21768266]
5.Zhou Y et al.. (2017) The Adenosine A1 Receptor Antagonist DPCPX Inhibits Tumor Progression via the ERK/JNK Pathway in Renal Cell Carcinoma.. Cell Physiol Biochem, 43 (2):(733-742). [PMID:28950257]
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A2305462