N-Didesmethyl Loperamide - 98%, high purity , CAS No.66164-06-5

  • ≥98%
Item Number
N347559
Grouped product items
SKUSizeAvailabilityPrice Qty
N347559-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$209.90
N347559-5mg
5mg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$285.90
N347559-10mg
10mg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$546.90
N347559-50mg
50mg
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$2,280.90

a metabolite of Loperamide

Basic Description

SynonymsLoperamid-M didesmethyl | FT-0666698 | N-Didesmethyl Loperamide | SCHEMBL2310814 | DTXSID10648790 | AKOS030255653 | R 21345; | 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylbutanamide | 4-(4-Chlorophenyl)-4-hydroxy-alpha,alpha-diphenyl-1-pipe
Specifications & Purity≥98%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

N-Didesmethyl Loperamide is a metabolite of Loperamide, a new and improved PET radiotracer for imaging P-gp function.

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CRT Chloroquine resistance transporter (206 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylbutanamide
INCHI InChI=1S/C27H29ClN2O2/c28-24-13-11-21(12-14-24)26(32)15-18-30(19-16-26)20-17-27(25(29)31,22-7-3-1-4-8-22)23-9-5-2-6-10-23/h1-14,32H,15-20H2,(H2,29,31)
InChi Key PXJHDOGGBLQFRX-UHFFFAOYSA-N
Canonical SMILES C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCC(C3=CC=CC=C3)(C4=CC=CC=C4)C(=O)N
Isomeric SMILES C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCC(C3=CC=CC=C3)(C4=CC=CC=C4)C(=O)N
PubChem CID 25129795
Molecular Weight 448.98

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in Chloroform and Methanol
Melt Point(°C)210-212° C

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