N-Formyl-Met-Leu-Phe - 97%, high purity , CAS No.59880-97-6, Agonist of FPR1;Agonist of FPR2/ALX

Item Number

F113682

• Synonyms: N-Formyl-Met-Leu-Phe|59880-97-6|FMLP|Chemotactic peptide|fMLF|N-Formyl-methionyl-leucyl-phenylalanine|F-Met-leu-phe|fMetLeuPhe|fMet-Leu-Phe|N-Formyl-L-methionyl-L-leucyl-L-phenylalanine|formyl-Met-Leu-Phe|N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE|(S)-2-((S)
• Specifications & Purity: Moligand™, ≥97%
• Biochemical and Physiological Mechanisms: N-Formyl-Met-Leu-Phe induced chemotaxis in phosphoinositide 3-kinase γ (PI3K)γ-/- neutrophils, and promotes adhesion, polymerization of F-actin, Fcγ receptor-mediated phagocytosis and intracellular Ca2+ release. It acts as an inflammatory agent and activa
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: AGONIST
• Mechanism of action: Agonist of FPR1;Agonist of FPR2/ALX
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

N-Formyl-Met-Leu-Phe has been used for:

· creating gradients in Zigmond chamber chemotaxis assay performed on neutrophils

· use in neutrophil chemotaix assayand

· determination of the involvement of MAPK-activating protein kinase-2 (MAPKAPK-2) and/or p38, in the signaling pathway of human polymorphonuclear leukocytes (PMNs) stimulated by N-Formyl-Met-Leu-Phe.