Basic Description

Synonyms	158982-15-1 \| N9-Isopropylolomoucine \| N9-ISOPROPYL-OLOMOUCINE \| 9-Isopropylolomoucine \| CHEMBL86066 \| 2-(2'-Hydroxyethylamino)-6-benzylamino-9-isopropylpurine \| 2-{[6-(benzylamino)-9-isopropyl-9H-purin-2-yl]amino}ethanol \| 2-(6-(benzylamino)-9-isopropyl-9H-purin-2-yla
Specifications & Purity	≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	N\|9\|-Isopropyl-olomoucine is an inhibitor of CDK1/cyclin B (IC\|50\|= 2 μM) and CDK5/p35 (IC\|50\|= 3 μM).

Product Properties

pKa	pKa: 4.76 (Predicted)
Ki Data	Cdk5: Ki= 1.26 μM (human); CLK2: Ki= 1.58 μM (human); Cdk2: Ki= 1.58 μM (human); HIPK4: Ki= 2.00 μM (human); CLK4: Ki= 2.5 μM (human)

Associated Targets(Human)

CSNK1D Tchem Casein kinase I delta (4546 Activities)

Discover Target: CSNK1D

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CACNA1B Tclin Voltage-gated N-type calcium channel alpha-1B subunit (743 Activities)

Discover Target: CACNA1B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CDK2 Tchem Cyclin-dependent kinase 2 (9050 Activities)

Discover Target: CDK2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CDK1 Tchem Cyclin-dependent kinase 1 (3927 Activities)

Discover Target: CDK1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DYRK1A Tchem Dual-specificity tyrosine-phosphorylation regulated kinase 1A (6484 Activities)

Discover Target: DYRK1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CDK5 Tchem Cyclin-dependent kinase 5 (3021 Activities)

Discover Target: CDK5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CLK2 Tchem Dual specificity protein kinase CLK2 (3942 Activities)

Discover Target: CLK2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CLK4 Tchem Dual specificity protein kinase CLK4 (4053 Activities)

Discover Target: CLK4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BJ (6930 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SRPK1 Tchem Serine/threonine-protein kinase SRPK1 (2359 Activities)

Discover Target: SRPK1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HIPK4 Tchem Homeodomain-interacting protein kinase 4 (1718 Activities)

Discover Target: HIPK4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	2-[[6-(benzylamino)-9-propan-2-ylpurin-2-yl]amino]ethanol
INCHI	InChI=1S/C17H22N6O/c1-12(2)23-11-20-14-15(19-10-13-6-4-3-5-7-13)21-17(18-8-9-24)22-16(14)23/h3-7,11-12,24H,8-10H2,1-2H3,(H2,18,19,21,22)
InChi Key	WHDJEAZLMYPLGL-UHFFFAOYSA-N
Canonical SMILES	CC(C)N1C=NC2=C(N=C(N=C21)NCCO)NCC3=CC=CC=C3
Isomeric SMILES	CC(C)N1C=NC2=C(N=C(N=C21)NCCO)NCC3=CC=CC=C3
WGK Germany	3
PubChem CID	6610355
Molecular Weight	326.4

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Solubility	Soluble in DMSO, DMF, and methanol (sparingly).
Refractive Index	n20D1.66 (Predicted)
Boil Point(°C)	574.87° C at 760 mmHg (Predicted)
Melt Point(°C)	230.70° C (Predicted)

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed
Precautionary Statements	P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help.
WGK Germany	3
RIDADR	NONHforallmodesoftransport

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SKU	Size	Availability	Price	Qty
N335798-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$171.90
N335798-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$617.90

N⁹-Isopropyl-olomoucine - ≥98%, high purity , CAS No.158982-15-1