N-Methylquipazine dimaleate , CAS No.28614-26-8

Item Number
N331461
Grouped product items
SKUSizeAvailabilityPrice Qty
N331461-20mg
20mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$84.90
N331461-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$132.90

a SR-3 agonist

Basic Description

SynonymsN-methylquipazine | 2-(4-methylpiperazin-1-yl)quinoline | 28614-26-8 | 0YV1ZIR6S0 | quinoline, 2-(4-methyl-1-piperazinyl)- | J366.838J | CHEMBL288591 | CHEBI:64164 | 1-(2-Quinolyl)-4-methylpiperazine | 2-(4-Methyl-piperazin-1-yl)-quinoline | NMethylquipazine | N Methylquipazin
Storage TempRoom temperature
Shipped InNormal
Product Description

N-Methylquipazine dimaleate is a tertiary amine analog of quipazine that is an agonist at SR (SR-3) with an affinity similar to that of quipazine, but which lacks affinity for central SR-1B.

Associated Targets(Human)

HTR3A Tclin 5-hydroxytryptamine receptor 3A (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR3A Tclin Serotonin 3a (5-HT3a) receptor (3366 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
THPO Tbio Thrombopoietin (834 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hrh4 Histamine H4 receptor (388 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Htr3a Serotonin 3 (5-HT3) receptor (1834 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 2-(4-methylpiperazin-1-yl)quinoline
INCHI InChI=1S/C14H17N3/c1-16-8-10-17(11-9-16)14-7-6-12-4-2-3-5-13(12)15-14/h2-7H,8-11H2,1H3
InChi Key HOMWNUXPSJQSSU-UHFFFAOYSA-N
Canonical SMILES CN1CCN(CC1)C2=NC3=CC=CC=C3C=C2
Isomeric SMILES CN1CCN(CC1)C2=NC3=CC=CC=C3C=C2
WGK Germany 3
PubChem CID 5013
Molecular Weight 227.3

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in water (50 mM), 0.1 M HCl, 0.1 M NaOH (slightly soluble), and ethanol (slightly soluble).
Refractive Indexn20D~1.62 (Predicted)
Boil Point(°C)379.5° C at 760 mmHg (Predicted)

Safety and Hazards(GHS)

WGK Germany 3

Related Documents

Solution Calculators