N-octanoyl-D-erythro-sphingosine - >99%, high purity , CAS No.74713-59-0

  • ≥99%
Item Number
N130616
Grouped product items
SKUSizeAvailabilityPrice Qty
N130616-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$68.90

Non-physiological and biologically active ceramide analog.

Basic Description

SynonymsC8 ceramide | C8-ceramide | 74713-59-0 | N-octanoylsphingosine | C-8 Ceramide | N-[(E,2S,3R)-1,3-dihydroxyoctadec-4-en-2-yl]octanamide | CHEBI:45815 | N-octanoyl-D-erythro-sphingosine | N-octanoyl sphingosine | N-octanoylsphing-4-enine | BSPBio_001569 | BML3-D01 | CHEMBL444463 | N
Specifications & Purity≥99%
Biochemical and Physiological MechanismsNon-physiological and biologically active ceramide analog. Various pharmacological activities including protein kinase activation, induces phosphorylation of EGF and apoptosis in vitro .
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

General description:

C8 Ceramide is a short chain ceramide and is cell permeable.


Application:

C8 Ceramide (d18:1/8:0) has been used as an internal ceramide standard in electrospray ionization. It has also been used as a substrate for ceramide kinase activity assay. It is suitable for use as a substrate for galactocerebrosidase.

Associated Targets(Human)

GBA1 Tclin Beta-glucocerebrosidase (14647 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDA-MB-468 (9477 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDA-MB-231 (73002 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Trypanosoma cruzi (99888 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ulva (10 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name N-[(E,2S,3R)-1,3-dihydroxyoctadec-4-en-2-yl]octanamide
INCHI InChI=1S/C26H51NO3/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(29)24(23-28)27-26(30)22-20-17-8-6-4-2/h19,21,24-25,28-29H,3-18,20,22-23H2,1-2H3,(H,27,30)/b21-19+/t24-,25+/m0/s1
InChi Key APDLCSPGWPLYEQ-WRBRXSDHSA-N
Canonical SMILES CCCCCCCCCCCCCC=CC(C(CO)NC(=O)CCCCCCC)O
Isomeric SMILES CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO)NC(=O)CCCCCCC)O
PubChem CID 5702614
Molecular Weight 425.688

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Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
F1701022Certificate of AnalysisJun 09, 2023 N130616
G2209174Certificate of AnalysisJun 17, 2022 N130616
B2219469Certificate of AnalysisJan 21, 2022 N130616

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