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N-Octyl-β-D-glucopyranoside - 97%, high purity , CAS No.29836-26-8

5 Citations

≥97%

CAS#: 29836-26-8
Formula: C₁₄H₂₈O₆
Molecular Weight: 292.37
Beilstein Registry Number: 17(5)7,38
MDL number: MFCD00063288
PubChem CID: 62852

Item Number

O105509

Grouped product items
SKU	Size	Availability	Price
O105509-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$19.90
O105509-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$69.90
O105509-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$239.90

Non-ionic detergent

View related series

Chemical Biology monosaccharide

Basic Description

Synonyms	OGP \| n-octyl-.beta.-d-glucopyranoside \| (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(octyloxy)oxane-3,4,5-triol \| AKOS015919434 \| NCGC00385963-01!(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-octoxyoxane-3,4,5-triol \| n-Octyl glucoside \| 1-Octyl beta-D-glucoside \| B-Oct
Specifications & Purity	≥97%
Biochemical and Physiological Mechanisms	Non-ionic detergent. Solubilizes membrane-bound proteins. Permeabilizes cell membranes of paraformaldehyde fixed cells. Forms self-assembled nanostructures in water.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Usually used as Non-ionic, dialyzable detergent for the solubilization and isolation of membrane proteins,and has been shown to increase the resolution of proteins in 2D gels. Octyl-beta-Glucoside is a nonionic detergent that has been widely used for membrane protein solubilization. • A low-molecular weight, nonionic detergent • Effective for membrane protein solubilization • Less stable and less commonly used than octylthioglucoside (OTG) • Can be removed from solution by dialysis • Optically clear; low absorbance at 280nm

Associated Targets(non-human)

lgtC Alpha 1,4 galactosyltransferase (29 Activities)

Discover Target: lgtC

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

waaC Lipopolysaccharide heptosyltransferase 1 (62 Activities)

Discover Target: waaC

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-octoxyoxane-3,4,5-triol
INCHI	InChI=1S/C14H28O6/c1-2-3-4-5-6-7-8-19-14-13(18)12(17)11(16)10(9-15)20-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14-/m1/s1
InChi Key	HEGSGKPQLMEBJL-RKQHYHRCSA-N
Canonical SMILES	CCCCCCCCOC1C(C(C(C(O1)CO)O)O)O
Isomeric SMILES	CCCCCCCCO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O
PubChem CID	62852
Molecular Weight	292.37
Beilstein	17(5)7,38
Reaxy-Rn	84118

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

15 results found

Lot Number	Certificate Type	Date	Item
K2425370	Certificate of Analysis	Nov 29, 2024	O105509
K2425371	Certificate of Analysis	Nov 29, 2024	O105509
K2425372	Certificate of Analysis	Nov 29, 2024	O105509
I2412573	Certificate of Analysis	Sep 23, 2024	O105509
I2412584	Certificate of Analysis	Sep 23, 2024	O105509
I2412586	Certificate of Analysis	Sep 23, 2024	O105509
J2114322	Certificate of Analysis	Jul 11, 2024	O105509
J2114323	Certificate of Analysis	Jul 11, 2024	O105509
J2114325	Certificate of Analysis	Jul 11, 2024	O105509
C2421586	Certificate of Analysis	Apr 09, 2024	O105509
C2421587	Certificate of Analysis	Apr 09, 2024	O105509
H2028067	Certificate of Analysis	Jun 09, 2023	O105509
F2302258	Certificate of Analysis	Jun 07, 2023	O105509
F2302259	Certificate of Analysis	Jun 07, 2023	O105509
F2302260	Certificate of Analysis	Jun 07, 2023	O105509

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Chemical and Physical Properties

Solubility	Soluble in water; Soluble in Methanol
Sensitivity	Hygroscopic
Specific Rotation[α]	-27° (C=1,MeOH)
Melt Point(°C)	105°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H228:Flammable solid
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use ... to extinguish. P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P240:Ground/bond container and receiving equipment. P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
Reaxy-Rn	84118
Merck Index	6767

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Jiaoming Dong,Yu Li,Xiumei Mo. (2012-12-27) The study of a new detergent (octyl-glucopyranoside) for decellularizing porcine pericardium as tissue engineering scaffold.. The Journal of surgical research, 183 ((1)): (56-67). [PMID:23267763]
2. Fei Liu, Yayun Qin, Yuwen Huang, Pan Gao, Jingzhen Li, Shanshan Yu, Danna Jia, Xiang Chen, Yuexia Lv, Jiayi Tu, Kui Sun, Yunqiao Han, James Reilly, Xinhua Shu, Qunwei Lu, Zhaohui Tang, Chengqi Xu, Daji Luo, Mugen Liu. (2022) Rod genesis driven by mafba in an nrl knockout zebrafish model with altered photoreceptor composition and progressive retinal degeneration. PLoS Genetics, 18 (3): (e1009841). [PMID:35245286] [10.1371/journal.pgen.1009841]
3. Zhang Peng, Wang Junqian, Ding Xuanwei, Lin Jun, Jiang Hao, Zhou Hongjun, Lu Yuan. (2019) Exploration of the Tolerance Ability of a Cell-Free Biosynthesis System to Toxic Substances. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 189 (4): (1096-1107). [PMID:31161383] [10.1007/s12010-019-03039-5]
4. Zhixia Liang, Yanbin Yun, Manxiang Wang, Guicheng Liu, Peng Lu, Woochul Yang, Chunli Li. (2019) Performance evaluation of interfacial polymerisation-fabricated aquaporin-based biomimetic membranes in forward osmosis. RSC Advances, 9 (19): (10715-10726). [PMID:35515303] [10.1039/C9RA00787C]
5. Pingping Meng, Shubo Deng, Ayiguli Maimaiti, Bin Wang, Jun Huang, Yujue Wang, Ian T. Cousins, Gang Yu. (2018) Efficient removal of perfluorooctane sulfonate from aqueous film-forming foam solution by aeration-foam collection. CHEMOSPHERE, 203 (263). [PMID:29625315] [10.1016/j.chemosphere.2018.03.183]

References

1. Koh KH et al.. (2019) Nonimmune cell-derived ICOS ligand functions as a renoprotective avß3 integrin-selective antagonist.. J Clin Invest, 129 (4): (1713-1726). [PMID:30747722]
2. Luke L Lairson,Andrew G Watts,Warren W Wakarchuk,Stephen G Withers. (2006-10-24) Using substrate engineering to harness enzymatic promiscuity and expand biological catalysis.. Nature chemical biology, 2 ((12)): (724-728). [PMID:17057723]
3. Parmjeet Randhawa,Noush Afarin Farasati,Yuchen Huang. (2007-09-26) BK Virus replication in vitro: limited effect of drugs interfering with viral uptake and intracellular transport.. Antimicrobial agents and chemotherapy, 51 ((12)): (4492-4494). [PMID:17893158]
4. M Chisari,H-J Shu,A Taylor,J H Steinbach,C F Zorumski,Steven Mennerick. (2010-04-24) Structurally diverse amphiphiles exhibit biphasic modulation of GABAA receptors: similarities and differences with neurosteroid actions.. British journal of pharmacology, 160 ((1)): (130-141). [PMID:20412070]
5. M Sakai,K Miyazawa,H Jitsumatsu,K Kamio,S Mitsuiki,N Toh,G Sugihara,W Norde. (2010-07-17) Resolution of D- and L-glucoses by chiral N-octyl-beta-D-glycoside-Cu(II) complex adsorbed at the gas/liquid interface of small bubbles.. Colloids and surfaces. B, Biointerfaces, 80 ((2)): (107-115). [PMID:20634045]
6. Chie Katsuda,Kanami Niiyama,Eriko Obana,Takenori Yamamoto,Yumiko Katou,Masatoshi Kataoka,Kazuto Ohkura,Yasuo Shinohara. (2010-07-22) Specific formation of trypsin-resistant micelles on a hydrophobic peptide observed with Triton X-100 but not with octylglucoside.. Biochimica et biophysica acta, 1798 ((11)): (2090-2093). [PMID:20646996]
7. Anniefer N Magpusao,Richard T Desmond,Katelyn J Billings,Gabriel Fenteany,Mark W Peczuh. (2010-08-17) Synthesis and evaluation of antimigratory and antiproliferative activities of lipid-linked [13]-macro-dilactones.. Bioorganic & medicinal chemistry letters, 20 ((18)): (5472-5476). [PMID:20709546]
8. Christine Ménager,Dihya Guemghar,Valérie Cabuil,Sylviane Lesieur. (2010-09-10) Interaction of n-octyl β,D-glucopyranoside with giant magnetic-fluid-loaded phosphatidylcholine vesicles: direct visualization of membrane curvature fluctuations as a function of surfactant partitioning between water and lipid bilayer.. Langmuir : the ACS journal of surfaces and colloids, 26 ((19)): (15453-15463). [PMID:20825201]
9. Shigesaburo Ogawa,Kouichi Asakura,Shuichi Osanai. (2010-10-05) Glass transition behavior of octyl β-D-glucoside and octyl β-D-thioglucoside/water binary mixtures.. Carbohydrate research, 345 ((17)): (2534-2541). [PMID:20889145]
10. Mohd Younis Rather,Saroj Mishra,Subhash Chand. (2010-10-12) β-Glucosidase catalyzed synthesis of octyl-β-D-glucopyranoside using whole cells of Pichia etchellsii in micro aqueous media.. Journal of biotechnology, 150 ((4)): (490-496). [PMID:20932864]
11. Matthew J Ranaghan,Sumie Shima,Lavosier Ramos,Daniel S Poulin,Gregg Whited,Sanguthevar Rajasekaran,Jeffery A Stuart,Arlene D Albert,Robert R Birge. (2010-10-23) Photochemical and thermal stability of green and blue proteorhodopsins: implications for protein-based bioelectronic devices.. The journal of physical chemistry. B, 114 ((44)): (14064-14070). [PMID:20964279]
12. Chaoqun Yao,Yalan Li,John E Donelson,Mary E Wilson. (2010-12-08) Proteomic examination of Leishmania chagasi plasma membrane proteins: Contrast between avirulent and virulent (metacyclic) parasite forms.. Proteomics. Clinical applications, 4 ((1)): (4-16). [PMID:21137013]
13. Jun Liu,Oliver J Fackelmayer,David B Hicks,Laura Preiss,Thomas Meier,Eric A Sobie,Terry A Krulwich. (2011-05-17) Mutations in a helix-1 motif of the ATP synthase c-subunit of Bacillus pseudofirmus OF4 cause functional deficits and changes in the c-ring stability and mobility on sodium dodecyl sulfate-polyacrylamide gel electrophoresis.. Biochemistry, 50 ((24)): (5497-5506). [PMID:21568349]
14. Mobeen Raja,Elisabeth Vales. (2011-05-17) Improved technique for reconstituting incredibly high and soluble amounts of tetrameric K⁺ channel in natural membranes.. The Journal of membrane biology, 241 ((3)): (141-144). [PMID:21573757]
15. Scott C Corley,Peter Sprangers,Arlene D Albert. (2011-06-22) The bilayer enhances rhodopsin kinetic stability in bovine rod outer segment disk membranes.. Biophysical journal, 100 ((12)): (2946-2954). [PMID:21689528]
16. J D Doran,A K Mohanty,T Fox. (2011-09-17) Resolving the challenge of measuring ligand binding to membrane proteins by combining analytical ultracentrifugation and light scattering photometry.. Journal of pharmaceutical sciences, 101 ((1)): (92-101). [PMID:21922461]
17. Douglas L Miller,Chunyan Dou. (2011-11-18) The influence of octyl β-D-glucopyranoside on cell lysis induced by ultrasonic cavitation.. The Journal of the Acoustical Society of America, 130 ((5)): (3482-3488). [PMID:22088023]
18. Baris E Polat,William M Deen,Robert Langer,Daniel Blankschtein. (2011-11-22) A physical mechanism to explain the delivery of chemical penetration enhancers into skin during transdermal sonophoresis - Insight into the observed synergism.. Journal of controlled release : official journal of the Controlled Release Society, 158 ((2)): (250-260). [PMID:22100440]
19. Kerry K Karukstis,Whitney C Duim,Gerald R Van Hecke,Nagiko Hara. (2012-03-06) Biologically relevant lyotropic liquid crystalline phases in mixtures of n-octyl β-D-glucoside and water. Determination of the phase diagram by fluorescence spectroscopy.. The journal of physical chemistry. B, 116 ((12)): (3816-3822). [PMID:22385304]
20. Zheng-Zheng Zou,Hui-Lei Yu,Chun-Xiu Li,Xin-Wen Zhou,Chihiro Hayashi,Jie Sun,Bao-Hong Liu,Tadeyuki Imanaka,Jian-He Xu. (2012-06-19) A new thermostable β-glucosidase mined from Dictyoglomus thermophilum: properties and performance in octyl glucoside synthesis at high temperatures.. Bioresource technology, 118 (425-430). [PMID:22705966]
21. Buenafe T Arachea,Zhen Sun,Nina Potente,Radhika Malik,Dragan Isailovic,Ronald E Viola. (2012-09-12) Detergent selection for enhanced extraction of membrane proteins.. Protein expression and purification, 86 ((1)): (12-20). [PMID:22963795]
22. Zahrabatoul Mosapour Kotena,Reza Behjatmanesh-Ardakani,Rauzah Hashim,Vijayan Manickam Achari. (2012-09-14) Hydrogen bonds in galactopyranoside and glucopyranoside: a density functional theory study.. Journal of molecular modeling, 19 ((2)): (589-599). [PMID:22972691]
23. Sanchari Banerjee,Krishnan Sankaran. (2012-11-21) First ever isolation of bacterial prolipoprotein diacylglyceryl transferase in single step from Lactococcus lactis.. Protein expression and purification, 87 ((2)): (120-128). [PMID:23165241]
24. Alison Kan,Abidali Mohamedali,Sock Hwee Tan,Harish R Cheruku,Iveta Slapetova,Ling Y Lee,Mark S Baker. (2012-12-04) An improved method for the detection and enrichment of low-abundant membrane and lipid raft-residing proteins.. Journal of proteomics, 79 (299-304). [PMID:23201117]
25. Jiaoming Dong,Yu Li,Xiumei Mo. (2012-12-27) The study of a new detergent (octyl-glucopyranoside) for decellularizing porcine pericardium as tissue engineering scaffold.. The Journal of surgical research, 183 ((1)): (56-67). [PMID:23267763]
26. Joana A Loureiro,Sandra Rocha,Maria do Carmo Pereira. (2013-08-08) Charged surfactants induce a non-fibrillar aggregation pathway of amyloid-beta peptide.. Journal of peptide science : an official publication of the European Peptide Society, 19 ((9)): (581-587). [PMID:23922329]
27. Jürgen Borlak,Prashant Singh,Giuseppe Gazzana. (2015-04-16) Proteome mapping of epidermal growth factor induced hepatocellular carcinomas identifies novel cell metabolism targets and mitogen activated protein kinase signalling events.. BMC genomics, 16 (124-124). [PMID:25872475]
28. Paul Y-J Hsu,Ching-An Wu,Shan-Shan Shen,Ya-Wun Yang. (2015-06-10) The role of tomatine adjuvant in antigen delivery for cross- presentation.. Current drug delivery, 12 ((3)): (342-350). [PMID:26054535]
29. Guilherme Kloster Spartalis,Lucas Kravchychyn Cappelletti,Amanda Cristina Schoeffel,Milton Domingos Michél,Thiago Amadei Pegoraro,César Augusto Galvão Arrais,Karin Hermana Neppelenbroek,Vanessa Migliorini Urban. (2015-10-07) Effect of conventional water-bath and experimental microwave polymerization cycles on the flexural properties of denture base acrylic resins.. Dental materials journal, 34 ((5)): (623-628). [PMID:26438986]
30. Mengqi Li,Chen-Song Zhang,Yue Zong,Jin-Wei Feng,Teng Ma,Meiqin Hu,Zhizhong Lin,Xiaotong Li,Changchuan Xie,Yaying Wu,Dong Jiang,Ying Li,Cixiong Zhang,Xiao Tian,Wen Wang,Yanyan Yang,Jie Chen,Jiwen Cui,Yu-Qing Wu,Xin Chen,Qing-Feng Liu,Jianfeng Wu,Shu-Yong Lin,Zhiyun Ye,Ying Liu,Hai-Long Piao,Li Yu,Zhuan Zhou,Xiao-Song Xie,D Grahame Hardie,Sheng-Cai Lin. (2019-06-18) Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK.. Cell metabolism, 30 ((3)): (508-524). [PMID:31204282]
31. Michael J Edwards,Katrin Anne Becker,Barbara Gripp,Markus Hoffmann,Simone Keitsch,Barbara Wilker,Matthias Soddemann,Anne Gulbins,Elisa Carpinteiro,Sameer H Patel,Gregory C Wilson,Stefan Pöhlmann,Silke Walter,Klaus Fassbender,Syed A Ahmad,Alexander Carpinteiro,Erich Gulbins. (2020-09-13) Sphingosine prevents binding of SARS-CoV-2 spike to its cellular receptor ACE2.. The Journal of biological chemistry, 295 ((45)): (15174-15182). [PMID:32917722]
32. Liron Feldberg,Ofir Schuster,Eytan Elhanany,Orly Laskar,Shmuel Yitzhaki,Sigalit Gura. (2019-11-30) Rapid and sensitive identification of ricin in environmental samples based on lactamyl agarose beads using LC-MS/MS (MRM).. Journal of mass spectrometry : JMS, 55 ((1)): (e4482-e4482). [PMID:31782217]
33. Ofir Schuster,Anat Zvi,Osnat Rosen,Hagit Achdout,Amir Ben-Shmuel,Ohad Shifman,Shmuel Yitzhaki,Orly Laskar,Liron Feldberg. (2021-02-16) Specific and Rapid SARS-CoV-2 Identification Based on LC-MS/MS Analysis.. ACS omega, 6 ((5)): (3525-3534). [PMID:33585737]
34. Fei Liu, Yayun Qin, Yuwen Huang, Pan Gao, Jingzhen Li, Shanshan Yu, Danna Jia, Xiang Chen, Yuexia Lv, Jiayi Tu, Kui Sun, Yunqiao Han, James Reilly, Xinhua Shu, Qunwei Lu, Zhaohui Tang, Chengqi Xu, Daji Luo, Mugen Liu. (2022) Rod genesis driven by mafba in an nrl knockout zebrafish model with altered photoreceptor composition and progressive retinal degeneration. PLoS Genetics, 18 (3): (e1009841). [PMID:35245286] [10.1371/journal.pgen.1009841]
35. Zhang Peng, Wang Junqian, Ding Xuanwei, Lin Jun, Jiang Hao, Zhou Hongjun, Lu Yuan. (2019) Exploration of the Tolerance Ability of a Cell-Free Biosynthesis System to Toxic Substances. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 189 (4): (1096-1107). [PMID:31161383] [10.1007/s12010-019-03039-5]
36. Zhixia Liang, Yanbin Yun, Manxiang Wang, Guicheng Liu, Peng Lu, Woochul Yang, Chunli Li. (2019) Performance evaluation of interfacial polymerisation-fabricated aquaporin-based biomimetic membranes in forward osmosis. RSC Advances, 9 (19): (10715-10726). [PMID:35515303] [10.1039/C9RA00787C]
37. Pingping Meng, Shubo Deng, Ayiguli Maimaiti, Bin Wang, Jun Huang, Yujue Wang, Ian T. Cousins, Gang Yu. (2018) Efficient removal of perfluorooctane sulfonate from aqueous film-forming foam solution by aeration-foam collection. CHEMOSPHERE, 203 (263). [PMID:29625315] [10.1016/j.chemosphere.2018.03.183]

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