N-p-Tosyl-L-phenylalanine chloromethyl ketone - 97%, high purity , CAS No.402-71-1

Item Number

T123226

• Synonyms: TPCK | 402-71-1 | TOSYLPHENYLALANYL CHLOROMETHYL KETONE | N-Tosyl-L-phenylalanyl chloromethyl ketone | N-Tosyl-L-phenylalanine chloromethyl ketone | Tos-Phe-CH2Cl | N-p-Tosyl-L-phenylalanine chloromethyl ketone | L-1-Tosylamido-2-phenylethyl chloromethyl ketone | (S)-N-(
• Specifications & Purity: ≥97%
• Biochemical and Physiological Mechanisms: Blocks the LPS- or cytokine-induced activation of nuclear factor κB (NFκB), which, in turn, blocks the induction of iNOS and COX-2 transcription. Blocks activation of pp70s6k by all mitogens. Blocks apoptosis cell lines by inhibiting the processing of cas
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

N-p-Tosyl-L-phenylalanine chloromethyl ketone has been used: to investigate whether transcription factor NFκB is involved in renalase expression to test the role of NF-κB activation to study its inhibitory effect on chymotrypsin