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SKU

Size

Availability

Price

Qty

N140440-25g

25g

In stock

$20.90

N140440-100g

100g

In stock

$75.90

N140440-500g

500g

Available within 4-8 weeks(?)

$338.90

Basic Description

Synonyms	2-ANILINOETHANOL \| 122-98-5 \| 2-(Phenylamino)ethanol \| N-Phenylethanolamine \| N-(2-Hydroxyethyl)aniline \| Ethanol, 2-(phenylamino)- \| Ethanol, 2-anilino- \| beta-Anilinoethanol \| 2-(phenylamino)ethan-1-ol \| N-(2-Hydroxyethyl)phenylamine \| phenylglycinol \| Aniline, N-(2-hydroxye
Specifications & Purity	≥98%(GC)
Storage Temp	Argon charged
Shipped In	Normal
Product Description	N-(2-Hydroxyethyl)aniline was employed as substrate for human olfactory UDP-glucuronosyltransferase. N-Phenylethanolamine is used as an intermediate for dyes and other organic compounds. Further, it is used as a substrate for human olfactory uridine 5'-diphospho-glucuronosyltransferase.

Associated Targets(Human)

UGT2A1 Tbio UDP-glucuronosyltransferase 2A1 (0 Activities)

Discover Target: UGT2A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UGT2A1 UDP-glucuronosyltransferase 2A1 (59 Activities)

Discover Target: UGT2A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

Pubchem Sid	488183141
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488183141
IUPAC Name	2-anilinoethanol
INCHI	InChI=1S/C8H11NO/c10-7-6-9-8-4-2-1-3-5-8/h1-5,9-10H,6-7H2
InChi Key	MWGATWIBSKHFMR-UHFFFAOYSA-N
Canonical SMILES	C1=CC=C(C=C1)NCCO
Isomeric SMILES	C1=CC=C(C=C1)NCCO
WGK Germany	2
RTECS	KJ7175000
PubChem CID	31235
Molecular Weight	137.18
Beilstein	774672

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

9 results found

Lot Number	Certificate Type	Date	Item
G2329253	Certificate of Analysis	Mar 01, 2023	N140440
G2329257	Certificate of Analysis	Mar 01, 2023	N140440
G2331230	Certificate of Analysis	Mar 01, 2023	N140440
B23021081	Certificate of Analysis	Nov 21, 2022	N140440
B23021118	Certificate of Analysis	Nov 21, 2022	N140440
B2302114	Certificate of Analysis	Nov 21, 2022	N140440
B2303519	Certificate of Analysis	Nov 21, 2022	N140440
B2309012	Certificate of Analysis	Nov 21, 2022	N140440
B2309013	Certificate of Analysis	Nov 21, 2022	N140440

Chemical and Physical Properties

Solubility	Slightly miscible with water
Sensitivity	air ,light sensitive
Refractive Index	1.5785
Flash Point(°F)	307°F
Flash Point(°C)	163°C
Boil Point(°C)	284-286°C
Melt Point(°C)	-30°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08, GHS09, GHS05
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H301:Toxic if swallowed H303:May be harmful if swallowed H310:Fatal in contact with skin
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P312:Call a POISON CENTER or doctor/... if you feel unwell. P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P337+P313:IF eye irritation persists: Get medical advice/attention. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P301:IF SWALLOWED: P391:Collect spillage. P330:Rinse mouth. P262:Do not get in eyes, on skin, or on clothing. P361+P364:Take off immediately all contaminated clothing and wash it before reuse.
WGK Germany	2
RTECS	KJ7175000

References

1. A P Owens,T Harrison,J D Moseley,C J Swain,S Sadowski,M A Cascieri. (1999-01-01) High affinity phenylglycinol-based NK1 receptor antagonists.. Bioorganic & medicinal chemistry letters, 8 ((1)): (51-56). [PMID:9871627]
2. G Jedlitschky,A J Cassidy,M Sales,N Pratt,B Burchell. (1999-06-09) Cloning and characterization of a novel human olfactory UDP-glucuronosyltransferase.. The Biochemical journal, 340 (( Pt 3)): (837-843). [PMID:10359671]
3. N Philippe,V Levacher,G Dupas,G Quéguiner,J Bourguignon. (2000-08-10) Diastereoselective protonation of lactam enolates derived from (R)-phenylglycinol. A novel asymmetric route to 4-phenyl-1,2,3, 4-tetrahydroisoquinolines.. Organic letters, 2 ((15)): (2185-2187). [PMID:10930239]
4. M Amat,N Llor,M Huguet,E Molins,E Espinosa,J Bosch. (2001-10-12) Unprecedented oxidation of a phenylglycinol-derived 2-pyridone: enantioselective synthesis of polyhydroxypiperidines.. Organic letters, 3 ((21)): (3257-3260). [PMID:11594808]
5. Kyo Han Ahn,Hui-Young Ku,Yusin Kim,Sung-Gon Kim,Young Kook Kim,Hyung Su Son,Ja Kang Ku. (2003-04-26) Fluorescence sensing of ammonium and organoammonium ions with tripodal oxazoline receptors.. Organic letters, 5 ((9)): (1419-1422). [PMID:12713288]
6. Janja Makarević,Milan Jokić,Zlata Raza,Zoran Stefanić,Biserka Kojić-Prodić,Mladen Zinić. (2003-11-26) Chiral bis(amino alcohol)oxalamide gelators-gelation properties and supramolecular organization: racemate versus pure enantiomer gelation.. Chemistry (Weinheim an der Bergstrasse, Germany), 9 ((22)): (5567-5580). [PMID:14639640]
7. Mercedes Amat,Maria Pérez,Núria Llor,Carmen Escolano,F Javier Luque,Elies Molins,Joan Bosch. (2004-12-04) Conjugate additions to phenylglycinol-derived unsaturated delta-lactams. Enantioselective synthesis of uleine alkaloids.. The Journal of organic chemistry, 69 ((25)): (8681-8693). [PMID:15575744]
8. Alok K Awasthi,Mark L Boys,Kimberly J Cain-Janicki,Pierre-Jean Colson,Wendel W Doubleday,Joseph E Duran,Payman N Farid. (2005-07-02) Practical enantioselective synthesis of beta-substituted-beta-amino esters.. The Journal of organic chemistry, 70 ((14)): (5387-5397). [PMID:15989317]
9. Mercedes Amat,Carmen Escolano,Oscar Lozano,Arantxa Gómez-Esqué,Rosa Griera,Elies Molins,Joan Bosch. (2006-05-06) Alkylation of phenylglycinol-derived oxazolopiperidone lactams. Enantioselective synthesis of beta-substituted piperidines.. The Journal of organic chemistry, 71 ((10)): (3804-3815). [PMID:16674053]
10. Mercedes Amat,Oriol Bassas,Núria Llor,Margalida Cantó,Maria Pérez,Elies Molins,Joan Bosch. (2006-07-20) Dynamic kinetic resolution and desymmetrization processes: a straightforward methodology for the enantioselective synthesis of piperidines.. Chemistry (Weinheim an der Bergstrasse, Germany), 12 ((30)): (7872-7881). [PMID:16850515]
11. Katarina Babić,G H M Driessen,A G J van der Ham,A B de Haan. (2006-10-19) Chiral separation of amino-alcohols using extractant impregnated resins.. Journal of chromatography. A, 1142 ((1)): (84-92). [PMID:17046774]
12. Siricharn S Jirapongphan,Juliusz Warzywoda,David E Budil,Albert Sacco. (2007-04-18) Enantioseparation of phenylglycinol in chiral-modified zeolite HY: a molecular simulation study.. Chirality, 19 ((6)): (514-517). [PMID:17437262]
13. Mercedes Amat,Oscar Lozano,Carmen Escolano,Elies Molins,Joan Bosch. (2007-05-10) Enantioselective synthesis of 3,3-disubstituted piperidine derivatives by enolate dialkylation of phenylglycinol-derived oxazolopiperidone lactams.. The Journal of organic chemistry, 72 ((12)): (4431-4439). [PMID:17488127]
14. Valentine J Klimkowski,Brian M Watson,Michael R Wiley,John Liebeschuetz,Jeffry B Franciskovich,Jothirajah Marimuthu,Jolie A Bastian,Daniel J Sall,Jeffrey K Smallwood,Nikolay Y Chirgadze,Gerald F Smith,Ronald S Foster,Trelia Craft,Philip Sipes,Marcia Chastain,Scott M Sheehan. (2007-09-21) D-phenylglycinol-derived non-covalent factor Xa inhibitors: effect of non-peptidic S4 linkage elements on affinity and anticoagulant activity.. Bioorganic & medicinal chemistry letters, 17 ((21)): (5801-5805). [PMID:17881231]
15. Marco Santarem,Corinne Vanucci-Bacqué,Gérard Lhommet. (2008-07-22) Formal total synthesis of (+)-gephyrotoxin.. The Journal of organic chemistry, 73 ((16)): (6466-6469). [PMID:18637692]
16. Mercedes Amat,Maria Pérez,Annamaria T Minaglia,Joan Bosch. (2008-08-01) An enantioselective synthetic route to cis-2,4-disubstituted and 2,4-bridged piperidines.. The Journal of organic chemistry, 73 ((17)): (6920-6923). [PMID:18666797]
17. Fui-Mee Ng,Matthew T Geballe,James P Snyder,Stephen F Traynelis,Chian-Ming Low. (2008-11-20) Structural insights into phenylethanolamines high-affinity binding site in NR2B from binding and molecular modeling studies.. Molecular brain, 1 (16-16). [PMID:19017396]
18. Santos Fustero,Natalia Mateu,Laia Albert,José Luis Aceña. (2009-05-15) Straightforward stereoselective access to cyclic peptidomimetics.. The Journal of organic chemistry, 74 ((11)): (4429-4432). [PMID:19438186]
19. Vincent Coeffard,Erwan Le Grognec,Isabelle Beaudet,Michel Evain,Jean-Paul Quintard. (2009-07-10) Synthesis of highly enantioenriched chiral alpha-aminoorganotins via diastereoselective ring opening of chiral N-(arenesulfonyl) 2-tributylstannyloxazolidines.. The Journal of organic chemistry, 74 ((16)): (5822-5838). [PMID:19586009]
20. Mercedes Amat,Carlos Arróniz,Elies Molins,Carmen Escolano,Joan Bosch. (2011-02-08) Highly stereoselective double (R)-phenylglycinol-induced cyclocondensation reactions of symmetric aryl bis(oxoacids).. Organic & biomolecular chemistry, 9 ((7)): (2175-2184). [PMID:21298149]
21. Eun Na Rae Cho,Yinan Li,Hee Jin Kim,Myung Ho Hyun. (2011-03-09) A colorimetric chiral sensor based on chiral crown ether for the recognition of the two enantiomers of primary amino alcohols and amines.. Chirality, 23 ((4)): (349-353). [PMID:21384440]
22. Harry G Brittain. (2012-09-22) Stereoselectivity in the salt-cocrystal products formed by phenylglycinol or phenylglycine with their respective sodium or hydrochloride salts.. Chirality, 25 ((1)): (8-15). [PMID:22996274]
23. M Verdú,A Bach,M Devant. (2015-06-27) Effect of concentrate feeder design on performance, eating and animal behavior, welfare, ruminal health, and carcass quality in Holstein bulls fed high-concentrate diets.. Journal of animal science, 93 ((6)): (3018-3033). [PMID:26115288]
24. Mercedes Amat,Begoña Checa,Núria Llor,Elies Molins,Joan Bosch. (2009-05-14) Enantioselective total synthesis of the indole alkaloid 16-episilicine.. Chemical communications (Cambridge, England), (20) ((20)): (2935-2937). [PMID:19436915]
25. Nadja Grobe,Xuan Ren,Toni M Kutchan,Meinhart H Zenk. (2010-11-26) An (R)-specific N-methyltransferase involved in human morphine biosynthesis.. Archives of biochemistry and biophysics, 506 ((1)): (42-47). [PMID:21093406]
26. Mercedes Amat,Núria Llor,Rosa Griera,Maria Pérez,Joan Bosch. (2011-05-13) Enantioselective synthesis of alkaloids from phenylglycinol-derived lactams.. Natural product communications, 6 ((4)): (515-526). [PMID:21560764]
27. Mercedes Amat,Maria Pérez,Joan Bosch. (2011-06-15) Stereoselective conjugate addition reactions to phenylglycinol-derived, unsaturated oxazolopiperidone lactams.. Chemistry (Weinheim an der Bergstrasse, Germany), 17 ((28)): (7724-7732). [PMID:21671295]

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N-Phenylethanolamine - ≥98.0%(GC), high purity , CAS No.122-98-5