Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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N422827-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $47.90 |
TRPV1 agonist. Capsaicin analog.
Synonyms | NONIVAMIDE | 2444-46-4 | N-Vanillylnonanamide | Pseudocapsaicin | Pelargonic acid vanillylamide | N-Vanillylnonamide | N-(4-Hydroxy-3-methoxybenzyl)nonanamide | N-Vanillylpelargonamide | Nonanoic acid vanillylamide | N-Nonanoyl vanillylamide | Vanillyl pelargonic amide | Vanil |
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Specifications & Purity | 10mM in DMSO |
Biochemical and Physiological Mechanisms | TRPV1 agonist. Less potent Capsaicin analog. Induces Ca 2+ release from ER. Blood-brain barrier permeable. Active in vivo . |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | N-[(4-hydroxy-3-methoxyphenyl)methyl]nonanamide |
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INCHI | InChI=1S/C17H27NO3/c1-3-4-5-6-7-8-9-17(20)18-13-14-10-11-15(19)16(12-14)21-2/h10-12,19H,3-9,13H2,1-2H3,(H,18,20) |
InChi Key | RGOVYLWUIBMPGK-UHFFFAOYSA-N |
Canonical SMILES | CCCCCCCCC(=O)NCC1=CC(=C(C=C1)O)OC |
Isomeric SMILES | CCCCCCCCC(=O)NCC1=CC(=C(C=C1)O)OC |
WGK Germany | 2 |
PubChem CID | 2998 |
UN Number | 2811 |
Molecular Weight | 293.4 |
Beilstein | 2144300 |
Enter Lot Number to search for COA:
Flash Point(°C) | 190°C |
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Melt Point(°C) | 58°C |
Pictogram(s) | GHS06, GHS08, GHS05, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H301:Toxic if swallowed H318:Causes serious eye damage H317:May cause an allergic skin reaction H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately. |
WGK Germany | 2 |
1. Jing Luo, Yijue Deng, Yi Ding, Ying Zhang, Min Tan, Guangning Xu, Huining Lin, Mengqing Wang, Chenguang Tang. (2023) Investigation into actions of Xiebai and Zengye decoction on cough sensitivity, airway inflammation and gut microbiota in the rat model of post-infectious cough. Heliyon, 9 (e22782). [PMID:38094068] [10.1016/j.heliyon.2023.e22782] |
2. Mingmai Bao, Jiahui Bai, Ying Wang, Suzhen Zhu, Yingchao Liu, Tianlun Wen, Jing Zhang, Shuang-cheng Ma, Yinlong Guo. (2023) Plasma-Excited Nebulizer Gas-Assisted Electrospray Ionization: Enhancing the Sensitivity of Pesticide in Mass Spectrometry. ANALYTICAL CHEMISTRY, 95 (40): (14842–14852). [PMID:37779463] [10.1021/acs.analchem.3c01502] |
3. Jing Luo, Yijue Deng, Yi Ding, Chenguang Tang, Mengqing Wang. (2023) Xiebai Zengye decoction improves respiratory function and attenuates inflammation in juvenile rats with postinfection cough via regulating ERK signaling pathway. CELL BIOCHEMISTRY AND FUNCTION, [PMID:37606071] [10.1002/cbf.3835] |
4. Tian-Lun Wen, Jia-Hui Bai, Ming-Mai Bao, Yong Qin, Yue Su, Yin-Long Guo. (2023) Ultrasonic sample introduction combined with flame assisted thermal ionization: Pretreatment-free direct mass spectrometry analysis for fraction collecting tubes of preparative liquid chromatography. TALANTA, 259 (124508). [PMID:37043878] [10.1016/j.talanta.2023.124508] |
5. Liangliang He, Huifang Duan, Xintong Chen, Yuanshan Chen, Qingmei Mo, Junqing Huang, Huinan Zhao, Xinsheng Yao, Jiaxu Chen, Zhihong Yao. (2023) Quality assessment of commercial dried ginger (Zingiber officinale Roscoe) based on targeted and non-targeted chemical profiles and anti-inflammatory activity. FOOD RESEARCH INTERNATIONAL, 166 (112589). [PMID:36914321] [10.1016/j.foodres.2023.112589] |
6. Zhang Jiali, Zhang Minghui, Yang Qingqing, Wei Lin, Yuan Bei, Pang Chengchen, Zhang Yanyan, Sun Xia, Guo Yemin. (2022) A simple and rapid homogeneous fluorescence polarization immunoassay for rapid identification of gutter cooking oil by detecting capsaicinoids. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 414 (20): (6127-6137). [PMID:35804073] [10.1007/s00216-022-04177-2] |
7. Pengfei Li, Jingkang Wang, Chunguo Wang, Long Cheng, Quantao Ma, Yaqi Li, Yongcheng An, Hongyu Dai, Yuhui Duan, Tieshan Wang, Xuan Ma, Minghui Zhang, Ting Wang, Baosheng Zhao. (2021) Therapeutic effects and mechanisms study of Hanchuan Zupa Granule in a Guinea pig model of cough variant asthma. JOURNAL OF ETHNOPHARMACOLOGY, 269 (113719). [PMID:33358856] [10.1016/j.jep.2020.113719] |
8. Liangchen Yue, Jun Cheng, Junjie Hua, Haiquan Dong, Junhu Zhou. (2021) A sodium percarbonate/ultraviolet system generated free radicals for degrading capsaicin to alleviate inhibition of methane production during anaerobic digestion of lipids and food waste. SCIENCE OF THE TOTAL ENVIRONMENT, 761 (143269). [PMID:33160666] [10.1016/j.scitotenv.2020.143269] |
9. Min Zhang, Ying Peng, Mengyue Wang, Beibei Gao, Lijuan Zhao, Xiaobo Li. (2019) The influence of compatibility of Si-Ni decoction with metabolism in intestinal bacteria on transports of toxic diterpenoid alkaloids from processed aconite root across Caco-2 monolayers. JOURNAL OF ETHNOPHARMACOLOGY, 228 (164). [PMID:30223050] [10.1016/j.jep.2018.09.022] |
10. Chuan Zhou, Dianping Ma, Wenming Cao, Haiming Shi, Yuanrong Jiang. (2018) Fast simultaneous determination of capsaicin, dihydrocapsaicin and nonivamide for detecting adulteration in edible and crude vegetable oils by UPLC-MS/MS. Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment, [PMID:29601258] [10.1080/19440049.2018.1457801] |
11. Jiajia Sun, Liqiang Liu, Shanshan Song, Gang Cui, Hua Kuang. (2018) Development of an immunochromatographic strip assay for three major capsaicinoids based on an ultrasensitive monoclonal antibody. FOOD AND AGRICULTURAL IMMUNOLOGY, [PMID:] [10.1080/09540105.2018.1490394] |
1. Jing Luo, Yijue Deng, Yi Ding, Ying Zhang, Min Tan, Guangning Xu, Huining Lin, Mengqing Wang, Chenguang Tang. (2023) Investigation into actions of Xiebai and Zengye decoction on cough sensitivity, airway inflammation and gut microbiota in the rat model of post-infectious cough. Heliyon, 9 (e22782). [PMID:38094068] [10.1016/j.heliyon.2023.e22782] |
2. Mingmai Bao, Jiahui Bai, Ying Wang, Suzhen Zhu, Yingchao Liu, Tianlun Wen, Jing Zhang, Shuang-cheng Ma, Yinlong Guo. (2023) Plasma-Excited Nebulizer Gas-Assisted Electrospray Ionization: Enhancing the Sensitivity of Pesticide in Mass Spectrometry. ANALYTICAL CHEMISTRY, 95 (40): (14842–14852). [PMID:37779463] [10.1021/acs.analchem.3c01502] |
3. Jing Luo, Yijue Deng, Yi Ding, Chenguang Tang, Mengqing Wang. (2023) Xiebai Zengye decoction improves respiratory function and attenuates inflammation in juvenile rats with postinfection cough via regulating ERK signaling pathway. CELL BIOCHEMISTRY AND FUNCTION, [PMID:37606071] [10.1002/cbf.3835] |
4. Tian-Lun Wen, Jia-Hui Bai, Ming-Mai Bao, Yong Qin, Yue Su, Yin-Long Guo. (2023) Ultrasonic sample introduction combined with flame assisted thermal ionization: Pretreatment-free direct mass spectrometry analysis for fraction collecting tubes of preparative liquid chromatography. TALANTA, 259 (124508). [PMID:37043878] [10.1016/j.talanta.2023.124508] |
5. Liangliang He, Huifang Duan, Xintong Chen, Yuanshan Chen, Qingmei Mo, Junqing Huang, Huinan Zhao, Xinsheng Yao, Jiaxu Chen, Zhihong Yao. (2023) Quality assessment of commercial dried ginger (Zingiber officinale Roscoe) based on targeted and non-targeted chemical profiles and anti-inflammatory activity. FOOD RESEARCH INTERNATIONAL, 166 (112589). [PMID:36914321] [10.1016/j.foodres.2023.112589] |
6. Zhang Jiali, Zhang Minghui, Yang Qingqing, Wei Lin, Yuan Bei, Pang Chengchen, Zhang Yanyan, Sun Xia, Guo Yemin. (2022) A simple and rapid homogeneous fluorescence polarization immunoassay for rapid identification of gutter cooking oil by detecting capsaicinoids. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 414 (20): (6127-6137). [PMID:35804073] [10.1007/s00216-022-04177-2] |
7. Pengfei Li, Jingkang Wang, Chunguo Wang, Long Cheng, Quantao Ma, Yaqi Li, Yongcheng An, Hongyu Dai, Yuhui Duan, Tieshan Wang, Xuan Ma, Minghui Zhang, Ting Wang, Baosheng Zhao. (2021) Therapeutic effects and mechanisms study of Hanchuan Zupa Granule in a Guinea pig model of cough variant asthma. JOURNAL OF ETHNOPHARMACOLOGY, 269 (113719). [PMID:33358856] [10.1016/j.jep.2020.113719] |
8. Liangchen Yue, Jun Cheng, Junjie Hua, Haiquan Dong, Junhu Zhou. (2021) A sodium percarbonate/ultraviolet system generated free radicals for degrading capsaicin to alleviate inhibition of methane production during anaerobic digestion of lipids and food waste. SCIENCE OF THE TOTAL ENVIRONMENT, 761 (143269). [PMID:33160666] [10.1016/j.scitotenv.2020.143269] |
9. Min Zhang, Ying Peng, Mengyue Wang, Beibei Gao, Lijuan Zhao, Xiaobo Li. (2019) The influence of compatibility of Si-Ni decoction with metabolism in intestinal bacteria on transports of toxic diterpenoid alkaloids from processed aconite root across Caco-2 monolayers. JOURNAL OF ETHNOPHARMACOLOGY, 228 (164). [PMID:30223050] [10.1016/j.jep.2018.09.022] |
10. Chuan Zhou, Dianping Ma, Wenming Cao, Haiming Shi, Yuanrong Jiang. (2018) Fast simultaneous determination of capsaicin, dihydrocapsaicin and nonivamide for detecting adulteration in edible and crude vegetable oils by UPLC-MS/MS. Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment, [PMID:29601258] [10.1080/19440049.2018.1457801] |
11. Jiajia Sun, Liqiang Liu, Shanshan Song, Gang Cui, Hua Kuang. (2018) Development of an immunochromatographic strip assay for three major capsaicinoids based on an ultrasensitive monoclonal antibody. FOOD AND AGRICULTURAL IMMUNOLOGY, [PMID:] [10.1080/09540105.2018.1490394] |