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N-Vanillylnonanamide - 97%, high purity , CAS No.2444-46-4

11 Citations

≥97%

CAS#: 2444-46-4
Formula: C₁₇H₂₇NO₃
Molecular Weight: 293.4
Beilstein Registry Number: 2144300
EC Number: 219-484-1
MDL number: MFCD00017286
PubChem CID: 2998

Item Number

V107237

Grouped product items
SKU	Size	Availability	Price
V107237-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$26.90
V107237-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$92.90
V107237-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$322.90
V107237-100g	100g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$904.90

TRPV1 agonist. Capsaicin analog.

View related series

alkaloid Membrane Transporter/Ion Channel Neuronal Signaling TRP Channel

Basic Description

Synonyms	N-Nonylvanylamide \| N-Pelargonic Acid Vanillylamide
Specifications & Purity	≥97%
Biochemical and Physiological Mechanisms	TRPV1 agonist. Less potent Capsaicin analog. Induces Ca 2+ release from ER. Blood-brain barrier permeable. Active in vivo .
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets(Human)

CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TRPV1 Tclin Vanilloid receptor (8273 Activities)

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ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

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NR1H4 Tclin Bile acid receptor FXR (6228 Activities)

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CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)

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ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)

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CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)

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CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)

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CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)

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CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

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HEK293 (82097 Activities)

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POLI Tchem DNA polymerase iota (116820 Activities)

Discover Target: POLI

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APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

Discover Target: APEX1

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EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

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BLM Tchem Bloom syndrome protein (4248 Activities)

Discover Target: BLM

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HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)

Discover Target: HPGD

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PMP22 Tbio Peripheral myelin protein 22 (699 Activities)

Discover Target: PMP22

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GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 Activities)

Discover Target: GLS

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Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

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Pseudomonas aeruginosa (123386 Activities)

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Klebsiella pneumoniae (43867 Activities)

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Staphylococcus aureus (210822 Activities)

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Acinetobacter baumannii (41033 Activities)

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Escherichia coli (133304 Activities)

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Cavia porcellus (23802 Activities)

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Mus musculus (284745 Activities)

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Rattus norvegicus (775804 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

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FTL Ferritin light chain (43324 Activities)

Discover Target: FTL

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

nfo Endonuclease 4 (425 Activities)

Discover Target: nfo

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Cell membrane (1233 Activities)

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Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	N-[(4-hydroxy-3-methoxyphenyl)methyl]nonanamide
INCHI	InChI=1S/C17H27NO3/c1-3-4-5-6-7-8-9-17(20)18-13-14-10-11-15(19)16(12-14)21-2/h10-12,19H,3-9,13H2,1-2H3,(H,18,20)
InChi Key	RGOVYLWUIBMPGK-UHFFFAOYSA-N
Canonical SMILES	CCCCCCCCC(=O)NCC1=CC(=C(C=C1)O)OC
Isomeric SMILES	CCCCCCCCC(=O)NCC1=CC(=C(C=C1)O)OC
WGK Germany	2
PubChem CID	2998
UN Number	2811
Molecular Weight	293.4
Beilstein	2144300

Certificates

Certificate of Analysis(COA)

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12 results found

Lot Number	Certificate Type	Date	Item
G2431589	Certificate of Analysis	Jul 12, 2024	V107237
G2431594	Certificate of Analysis	Jul 12, 2024	V107237
G2431595	Certificate of Analysis	Jul 12, 2024	V107237
G1502115	Certificate of Analysis	Apr 11, 2023	V107237
E1809121	Certificate of Analysis	Mar 31, 2022	V107237
C2204100	Certificate of Analysis	Mar 09, 2022	V107237
C2315441	Certificate of Analysis	Feb 24, 2022	V107237
F2208279	Certificate of Analysis	Feb 24, 2022	V107237
F2208280	Certificate of Analysis	Feb 24, 2022	V107237
F2208281	Certificate of Analysis	Feb 24, 2022	V107237
H2312261	Certificate of Analysis	Feb 24, 2022	V107237
J2324012	Certificate of Analysis	Feb 24, 2022	V107237

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Chemical and Physical Properties

Solubility	Soluble in chloroform
Flash Point(°C)	190°C
Melt Point(°C)	58°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08, GHS05, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H301:Toxic if swallowed H318:Causes serious eye damage H317:May cause an allergic skin reaction H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately.
WGK Germany	2

Alternative Products

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Jing Luo, Yijue Deng, Yi Ding, Ying Zhang, Min Tan, Guangning Xu, Huining Lin, Mengqing Wang, Chenguang Tang. (2023) Investigation into actions of Xiebai and Zengye decoction on cough sensitivity, airway inflammation and gut microbiota in the rat model of post-infectious cough. Heliyon, 9 (e22782). [PMID:38094068] [10.1016/j.heliyon.2023.e22782]
2. Mingmai Bao, Jiahui Bai, Ying Wang, Suzhen Zhu, Yingchao Liu, Tianlun Wen, Jing Zhang, Shuang-cheng Ma, Yinlong Guo. (2023) Plasma-Excited Nebulizer Gas-Assisted Electrospray Ionization: Enhancing the Sensitivity of Pesticide in Mass Spectrometry. ANALYTICAL CHEMISTRY, 95 (40): (14842–14852). [PMID:37779463] [10.1021/acs.analchem.3c01502]
3. Jing Luo, Yijue Deng, Yi Ding, Chenguang Tang, Mengqing Wang. (2023) Xiebai Zengye decoction improves respiratory function and attenuates inflammation in juvenile rats with postinfection cough via regulating ERK signaling pathway. CELL BIOCHEMISTRY AND FUNCTION, [PMID:37606071] [10.1002/cbf.3835]
4. Tian-Lun Wen, Jia-Hui Bai, Ming-Mai Bao, Yong Qin, Yue Su, Yin-Long Guo. (2023) Ultrasonic sample introduction combined with flame assisted thermal ionization: Pretreatment-free direct mass spectrometry analysis for fraction collecting tubes of preparative liquid chromatography. TALANTA, 259 (124508). [PMID:37043878] [10.1016/j.talanta.2023.124508]
5. Liangliang He, Huifang Duan, Xintong Chen, Yuanshan Chen, Qingmei Mo, Junqing Huang, Huinan Zhao, Xinsheng Yao, Jiaxu Chen, Zhihong Yao. (2023) Quality assessment of commercial dried ginger (Zingiber officinale Roscoe) based on targeted and non-targeted chemical profiles and anti-inflammatory activity. FOOD RESEARCH INTERNATIONAL, 166 (112589). [PMID:36914321] [10.1016/j.foodres.2023.112589]
6. Zhang Jiali, Zhang Minghui, Yang Qingqing, Wei Lin, Yuan Bei, Pang Chengchen, Zhang Yanyan, Sun Xia, Guo Yemin. (2022) A simple and rapid homogeneous fluorescence polarization immunoassay for rapid identification of gutter cooking oil by detecting capsaicinoids. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 414 (20): (6127-6137). [PMID:35804073] [10.1007/s00216-022-04177-2]
7. Pengfei Li, Jingkang Wang, Chunguo Wang, Long Cheng, Quantao Ma, Yaqi Li, Yongcheng An, Hongyu Dai, Yuhui Duan, Tieshan Wang, Xuan Ma, Minghui Zhang, Ting Wang, Baosheng Zhao. (2021) Therapeutic effects and mechanisms study of Hanchuan Zupa Granule in a Guinea pig model of cough variant asthma. JOURNAL OF ETHNOPHARMACOLOGY, 269 (113719). [PMID:33358856] [10.1016/j.jep.2020.113719]
8. Liangchen Yue, Jun Cheng, Junjie Hua, Haiquan Dong, Junhu Zhou. (2021) A sodium percarbonate/ultraviolet system generated free radicals for degrading capsaicin to alleviate inhibition of methane production during anaerobic digestion of lipids and food waste. SCIENCE OF THE TOTAL ENVIRONMENT, 761 (143269). [PMID:33160666] [10.1016/j.scitotenv.2020.143269]
9. Min Zhang, Ying Peng, Mengyue Wang, Beibei Gao, Lijuan Zhao, Xiaobo Li. (2019) The influence of compatibility of Si-Ni decoction with metabolism in intestinal bacteria on transports of toxic diterpenoid alkaloids from processed aconite root across Caco-2 monolayers. JOURNAL OF ETHNOPHARMACOLOGY, 228 (164). [PMID:30223050] [10.1016/j.jep.2018.09.022]
10. Chuan Zhou, Dianping Ma, Wenming Cao, Haiming Shi, Yuanrong Jiang. (2018) Fast simultaneous determination of capsaicin, dihydrocapsaicin and nonivamide for detecting adulteration in edible and crude vegetable oils by UPLC-MS/MS. Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment, [PMID:29601258] [10.1080/19440049.2018.1457801]
11. Jiajia Sun, Liqiang Liu, Shanshan Song, Gang Cui, Hua Kuang. (2018) Development of an immunochromatographic strip assay for three major capsaicinoids based on an ultrasensitive monoclonal antibody. FOOD AND AGRICULTURAL IMMUNOLOGY, [PMID:] [10.1080/09540105.2018.1490394]

References

1. Jing Luo, Yijue Deng, Yi Ding, Ying Zhang, Min Tan, Guangning Xu, Huining Lin, Mengqing Wang, Chenguang Tang. (2023) Investigation into actions of Xiebai and Zengye decoction on cough sensitivity, airway inflammation and gut microbiota in the rat model of post-infectious cough. Heliyon, 9 (e22782). [PMID:38094068] [10.1016/j.heliyon.2023.e22782]
2. Mingmai Bao, Jiahui Bai, Ying Wang, Suzhen Zhu, Yingchao Liu, Tianlun Wen, Jing Zhang, Shuang-cheng Ma, Yinlong Guo. (2023) Plasma-Excited Nebulizer Gas-Assisted Electrospray Ionization: Enhancing the Sensitivity of Pesticide in Mass Spectrometry. ANALYTICAL CHEMISTRY, 95 (40): (14842–14852). [PMID:37779463] [10.1021/acs.analchem.3c01502]
3. Jing Luo, Yijue Deng, Yi Ding, Chenguang Tang, Mengqing Wang. (2023) Xiebai Zengye decoction improves respiratory function and attenuates inflammation in juvenile rats with postinfection cough via regulating ERK signaling pathway. CELL BIOCHEMISTRY AND FUNCTION, [PMID:37606071] [10.1002/cbf.3835]
4. Tian-Lun Wen, Jia-Hui Bai, Ming-Mai Bao, Yong Qin, Yue Su, Yin-Long Guo. (2023) Ultrasonic sample introduction combined with flame assisted thermal ionization: Pretreatment-free direct mass spectrometry analysis for fraction collecting tubes of preparative liquid chromatography. TALANTA, 259 (124508). [PMID:37043878] [10.1016/j.talanta.2023.124508]
5. Liangliang He, Huifang Duan, Xintong Chen, Yuanshan Chen, Qingmei Mo, Junqing Huang, Huinan Zhao, Xinsheng Yao, Jiaxu Chen, Zhihong Yao. (2023) Quality assessment of commercial dried ginger (Zingiber officinale Roscoe) based on targeted and non-targeted chemical profiles and anti-inflammatory activity. FOOD RESEARCH INTERNATIONAL, 166 (112589). [PMID:36914321] [10.1016/j.foodres.2023.112589]
6. Zhang Jiali, Zhang Minghui, Yang Qingqing, Wei Lin, Yuan Bei, Pang Chengchen, Zhang Yanyan, Sun Xia, Guo Yemin. (2022) A simple and rapid homogeneous fluorescence polarization immunoassay for rapid identification of gutter cooking oil by detecting capsaicinoids. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 414 (20): (6127-6137). [PMID:35804073] [10.1007/s00216-022-04177-2]
7. Pengfei Li, Jingkang Wang, Chunguo Wang, Long Cheng, Quantao Ma, Yaqi Li, Yongcheng An, Hongyu Dai, Yuhui Duan, Tieshan Wang, Xuan Ma, Minghui Zhang, Ting Wang, Baosheng Zhao. (2021) Therapeutic effects and mechanisms study of Hanchuan Zupa Granule in a Guinea pig model of cough variant asthma. JOURNAL OF ETHNOPHARMACOLOGY, 269 (113719). [PMID:33358856] [10.1016/j.jep.2020.113719]
8. Liangchen Yue, Jun Cheng, Junjie Hua, Haiquan Dong, Junhu Zhou. (2021) A sodium percarbonate/ultraviolet system generated free radicals for degrading capsaicin to alleviate inhibition of methane production during anaerobic digestion of lipids and food waste. SCIENCE OF THE TOTAL ENVIRONMENT, 761 (143269). [PMID:33160666] [10.1016/j.scitotenv.2020.143269]
9. Min Zhang, Ying Peng, Mengyue Wang, Beibei Gao, Lijuan Zhao, Xiaobo Li. (2019) The influence of compatibility of Si-Ni decoction with metabolism in intestinal bacteria on transports of toxic diterpenoid alkaloids from processed aconite root across Caco-2 monolayers. JOURNAL OF ETHNOPHARMACOLOGY, 228 (164). [PMID:30223050] [10.1016/j.jep.2018.09.022]
10. Chuan Zhou, Dianping Ma, Wenming Cao, Haiming Shi, Yuanrong Jiang. (2018) Fast simultaneous determination of capsaicin, dihydrocapsaicin and nonivamide for detecting adulteration in edible and crude vegetable oils by UPLC-MS/MS. Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment, [PMID:29601258] [10.1080/19440049.2018.1457801]
11. Jiajia Sun, Liqiang Liu, Shanshan Song, Gang Cui, Hua Kuang. (2018) Development of an immunochromatographic strip assay for three major capsaicinoids based on an ultrasensitive monoclonal antibody. FOOD AND AGRICULTURAL IMMUNOLOGY, [PMID:] [10.1080/09540105.2018.1490394]

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N-Vanillylnonanamide - 97%, high purity , CAS No.2444-46-4

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Show more⌵

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Alternative Products

Citations of This Product

References

Solution Calculators

Molarity Calculator

Dilution Calculator

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