N2-Methyl-L-arginine - 96%, high purity , CAS No.2480-28-6

  • ≥96%
Item Number
N287385
Grouped product items
SKUSizeAvailabilityPrice Qty
N287385-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$155.90
N287385-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$239.90
N287385-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$918.90

Lysosomal system c L-arginine uptake inhibitor

Basic Description

SynonymsN~2~-methyl-L-arginine | (2S)-5-guanidino-2-(methylamino)pentanoic acid | (2S)-5-(diaminomethylideneamino)-2-(methylamino)pentanoic acid | 88RBJ4ZE9R | (S)-5-Guanidino-2-methylamino-pentanoic acid | J-015678 | UNII-88RBJ4ZE9R | (2S)-5-{[amino(imino)methyl
Specifications & Purity≥96%
Biochemical and Physiological MechanismsSelective L-arginine uptake inhibitor (Ki= 500μM). Inhibits uptake of arginine by the lysosomal system c in human fibroblastin vitro.
Storage TempRoom temperature
Shipped InNormal

Associated Targets(Human)

NOS1 Tchem Nitric oxide synthase, brain (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NOS3 Tchem Nitric oxide synthase, endothelial (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NOS1 Tchem Nitric-oxide synthase, brain (1786 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NOS3 Tchem Nitric-oxide synthase, endothelial (1452 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NOS1 Tchem Nitric oxide sythases; iNOS & nNOS (685 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAW264.7 (28094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (2S)-5-(diaminomethylideneamino)-2-(methylamino)pentanoic acid
INCHI InChI=1S/C7H16N4O2/c1-10-5(6(12)13)3-2-4-11-7(8)9/h5,10H,2-4H2,1H3,(H,12,13)(H4,8,9,11)/t5-/m0/s1
InChi Key NTWVQPHTOUKMDI-YFKPBYRVSA-N
Canonical SMILES CNC(CCCN=C(N)N)C(=O)O
Isomeric SMILES CN[C@@H](CCCN=C(N)N)C(=O)O
PubChem CID 73046
Molecular Weight 188.23

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

SolubilitySolvent:water, Max Conc. mg/mL: 18.82, Max Conc. mM: 100

Related Documents

Solution Calculators