Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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N129378-250mg | 250mg | In stock | $58.90 | |
N129378-1g | 1g | In stock | $178.90 |
Synonyms | Tox21_112239_1 | CCG-213817 | NDFX | NSC 759622 | Acuatim (TN) | N0931 | 8-(4-hydroxy-1-piperidyl)-9-fluoro-5-methyl-6,7-dihydro-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid | NADIFLOXACIN [MI] | Nadifloxacinum [INN-Latin] | S-Nadifloxacin | 9-fluor |
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Specifications & Purity | ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | Nadifloxacin is a cell-permeable, synthetic, broad-spectrum fluoroquinolone antibiotic that inhibits the growth of both gram-positive and gram-negative microbes. Studies suggest that the mechanism of inhibition occurs by interfering with DNA replication. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | A fluoroquinolone broad spectrum antibiotic. |
ALogP | 2.9 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
---|---|---|---|---|---|---|---|
Estrogen receptor alpha agonist | AGONIST | ALA206 | Estrogen receptor alpha | SINGLE PROTEIN | Homo sapiens | PubMed: [1] | |
Estrogen receptor alpha modulator | MODULATOR | ALA206 | Estrogen receptor alpha | SINGLE PROTEIN | Homo sapiens | ||
Estrogen receptor alpha agonist | AGONIST | ALA206 | Estrogen receptor alpha | SINGLE PROTEIN | Homo sapiens | PubMed: [1] | |
Estrogen receptor alpha agonist | AGONIST | ALA206 | Estrogen receptor alpha | SINGLE PROTEIN | Homo sapiens | ||
Estrogen receptor alpha agonist | AGONIST | ALA206 | Estrogen receptor alpha | SINGLE PROTEIN | Homo sapiens | ||
Estrogen receptor alpha agonist | AGONIST | ALA206 | Estrogen receptor alpha | SINGLE PROTEIN | Homo sapiens | DailyMed: [1] | |
Estrogen receptor alpha modulator | MODULATOR | ALA206 | Estrogen receptor alpha | SINGLE PROTEIN | Homo sapiens | ||
Estrogen receptor alpha agonist | AGONIST | ALA206 | Estrogen receptor alpha | SINGLE PROTEIN | Homo sapiens | ISBN: [1] | |
Estrogen receptor alpha agonist | AGONIST | ALA206 | Estrogen receptor alpha | SINGLE PROTEIN | Homo sapiens | ||
Estrogen receptor alpha agonist | AGONIST | ALA206 | Estrogen receptor alpha | SINGLE PROTEIN | Homo sapiens |
Pubchem Sid | 488179832 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488179832 |
IUPAC Name | 7-fluoro-8-(4-hydroxypiperidin-1-yl)-12-methyl-4-oxo-1-azatricyclo[7.3.1.05,13]trideca-2,5,7,9(13)-tetraene-3-carboxylic acid |
INCHI | InChI=1S/C19H21FN2O4/c1-10-2-3-12-16-13(18(24)14(19(25)26)9-22(10)16)8-15(20)17(12)21-6-4-11(23)5-7-21/h8-11,23H,2-7H2,1H3,(H,25,26) |
InChi Key | JYJTVFIEFKZWCJ-UHFFFAOYSA-N |
Canonical SMILES | CC1CCC2=C3N1C=C(C(=O)C3=CC(=C2N4CCC(CC4)O)F)C(=O)O |
Isomeric SMILES | CC1CCC2=C3N1C=C(C(=O)C3=CC(=C2N4CCC(CC4)O)F)C(=O)O |
PubChem CID | 4410 |
Molecular Weight | 360.38 |
Find and download the COA for your product by matching the lot number on the packaging.
4 results found
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
Certificate of Analysis | Feb 07, 2025 | N129378 | |
Certificate of Analysis | Feb 07, 2025 | N129378 | |
Certificate of Analysis | Feb 07, 2025 | N129378 | |
Certificate of Analysis | Feb 06, 2023 | N129378 |
Solubility | Soluble in DMSO (20 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C). |
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Sensitivity | Heat sensitive |
Melt Point(°C) | 245-251°C |
Pictogram(s) | GHS08 |
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Signal | Warning |
Hazard Statements | H373:Causes damage to organs through prolonged or repeated exposure H362:May cause harm to breast-fed children |
Precautionary Statements | P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P263:Avoid contact during pregnancy/while nursing. P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice. P319:Get medical help if you feel unwell. |
Merck Index | 6345 |