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Naftopidil DiHCl - 97%, high purity , CAS No.57149-08-3
Basic Description
| Synonyms | s1387 | Naftopidil.Dihydrochloride | NCGC00094247-01 | trans-trans-2,4-nonadienal | 1-[4-(2-methoxyphenyl)-1-piperazinyl]-3-(1-naphthoxy)-2-propanol dihydrochloride | 1-(4-(2-methoxyphenyl)piperazin-1-yl)-3-(naphthalen-1-yloxy)propan-2-ol dihydrochloride |
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| Specifications & Purity | ≥97% |
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| Storage Temp | Store at -20°C |
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| Shipped In | Ice chest + Ice pads |
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| Product Description | Naftopidil DiHCl is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively. |
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Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol;dihydrochloride |
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| INCHI | InChI=1S/C24H28N2O3.2ClH/c1-28-24-11-5-4-10-22(24)26-15-13-25(14-16-26)17-20(27)18-29-23-12-6-8-19-7-2-3-9-21(19)23;;/h2-12,20,27H,13-18H2,1H3;2*1H |
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| InChi Key | HZVCEQMJXMUXJF-UHFFFAOYSA-N |
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| Canonical SMILES | COC1=CC=CC=C1N2CCN(CC2)CC(COC3=CC=CC4=CC=CC=C43)O.Cl.Cl |
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| Isomeric SMILES | COC1=CC=CC=C1N2CCN(CC2)CC(COC3=CC=CC4=CC=CC=C43)O.Cl.Cl |
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| PubChem CID | 11957660 |
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| Molecular Weight | 465.41 |
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Chemical and Physical Properties
| Solubility | DMSO 41 mg/mL Water <1 mg/mL Ethanol 2 mg/mL |
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I2205098