Naphazoline hydrochloride - 99%, high purity , Adrenergic receptor alpha agonist, CAS No.550-99-2, Adrenergic receptor alpha agonist

  • ≥99%
Item Number
N113459
Grouped product items
SKUSizeAvailabilityPrice Qty
N113459-1g
1g
In stock
$18.90
N113459-5g
5g
In stock
$70.90
N113459-25g
25g
In stock
$319.90
N113459-100g
100g
In stock
$1,150.90
N113459-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$5,175.90

Basic Description

SynonymsSanorin | Tox21_111255 | 2-(1-Naphthylmethyl)-2-imidazoline monohydrochloride | Clera hydrochloride | Naphazoline hydrochloride (Naphcon) | Naphazoline hydrochloride [USP:JAN] | CCG-40122 | Naphazoline hydrochloride [JAN] | Niazol | Opcon | s2519 | SCHEMB
Specifications & Purity≥99%
Shipped InNormal
Action TypeAGONIST
Mechanism of actionAdrenergic receptor alpha agonist
Product Description

Naphazoline HCl is an ocular vasoconstrictor and imidazoline derivative sympathomimetic amine.

Associated Targets(Human)

GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MBNL1 Tbio Muscleblind-like protein 1 (34431 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Taar1 Trace amine-associated receptor 1 (899 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Adra1b Adrenergic receptor alpha-1 (5652 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Adra2c Adrenergic receptor alpha-2 (3313 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TyR1 (19 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488181252
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488181252
IUPAC Name 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole;hydrochloride
INCHI InChI=1S/C14H14N2.ClH/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14;/h1-7H,8-10H2,(H,15,16);1H
InChi Key DJDFFEBSKJCGHC-UHFFFAOYSA-N
Canonical SMILES C1CN=C(N1)CC2=CC=CC3=CC=CC=C32.Cl
Isomeric SMILES C1CN=C(N1)CC2=CC=CC3=CC=CC=C32.Cl
WGK Germany 3
RTECS NJ4375000
PubChem CID 11079
UN Number 2811
Molecular Weight 246.74
Reaxy-Rn 3716843

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

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2 results found

Lot NumberCertificate TypeDateItem
E2406042Certificate of AnalysisMay 14, 2024 N113459
D2321384Certificate of AnalysisAug 11, 2021 N113459

Chemical and Physical Properties

SolubilitySoluble in water 170 g/L, alcohol, DMSO, ethanol.
SensitivityHygroscopic
Melt Point(°C)254-260°C

Safety and Hazards(GHS)

Pictogram(s) GHS06
Signal Danger
Hazard Statements

H300:Fatal if swallowed

Precautionary Statements

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

WGK Germany 3
RTECS NJ4375000
Reaxy-Rn 3716843
Merck Index 6368

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