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Acetylcholine turnover
naphthylvinylmethylpyridine , CAS No.N612159, Inhibitor of choline O-acetyltransferase

naphthylvinylmethylpyridine , CAS No.N612159, Inhibitor of choline O-acetyltransferase

Item Number

N612159

Grouped product items
SKU	Size	Availability	Price	Qty
N612159-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
N612159-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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Basic Description

Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of choline O-acetyltransferase

CHAT Tchem Choline O-acetyltransferase (2 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	1-methyl-4-[(E)-2-naphthalen-1-ylethenyl]pyridin-1-ium
INCHI	InChI=1S/C18H16N/c1-19-13-11-15(12-14-19)9-10-17-7-4-6-16-5-2-3-8-18(16)17/h2-14H,1H3/q+1/b10-9+
InChi Key	FJFKCRZPKGCGJE-MDZDMXLPSA-N
Canonical SMILES	C[n+]1ccc(cc1)/C=C/c1cccc2c1cccc2
Isomeric SMILES	C[N+]1=CC=C(C=C1)/C=C/C2=CC=CC3=CC=CC=C32
PubChem CID	5758582

PubChem CID	5758582
ChEMBL Ligand	CHEMBL106212

Enter Lot Number to search for COA:

1. Gray AP, Platz RD, Henderson TR, Chang TC, Takahashi K, Dretchen KL. (1988) Approaches to protection against nerve agent poisoning. (Naphthylvinyl)pyridine derivatives as potential antidotes.. J Med Chem, 31 (4): (807-14). [PMID:3351860] [10.1021/op500134e]
2. White HL, Cavallito CJ. (1970) Inhibition of bacterial and mammalian choline acetyltransferases by styrylpyridine analogues.. J Neurochem, 17 (11): (1579-89). [PMID:5474659] [10.1021/op500134e]

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