Nastorazepide - 98%, high purity , CAS No.209219-38-5, Antagonist of CCK 2 receptor

Item Number
N413682
Grouped product items
SKUSizeAvailabilityPrice Qty
N413682-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$45.90
N413682-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$129.90
N413682-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$179.90
N413682-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$344.90
N413682-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$525.90
N413682-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$757.90
View related series
CCK2 receptor Antagonist

Basic Description

SynonymsA924416 | Q27089277 | D87151 | EX-A1929 | CHEBI:166857 | HY-138941 | NASTORAZEPIDE [INN] | R-(-)-Z-360 Free acid | GTPL907 | (R)-(-)-3-[3-(1-tert-butylcarbonylmethyl-2-oxo-5-cyclohexyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-3-yl)ureido]benzoic acid | NCG
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsNastorazepide (Z-360) is a selective, orally available antagonist of 1,5-benzodiazepine-derivative gastrin/cholecystokinin 2 (CCK-2) receptor with potential antineoplastic activity.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeANTAGONIST
Mechanism of actionAntagonist of CCK 2 receptor
Product Description

Information

Nastorazepide (Z-360) is a selective, orally available antagonist of 1,5-benzodiazepine-derivative gastrin/cholecystokinin 2 (CCK-2) receptor with potential antineoplastic activity.

Associated Targets(Human)

CCKBR Tclin Gastrin/cholecystokinin type B receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 3-[[(3R)-1-cyclohexyl-5-(3,3-dimethyl-2-oxobutyl)-4-oxo-2,3-dihydro-1,5-benzodiazepin-3-yl]carbamoylamino]benzoic acid
INCHI InChI=1S/C29H36N4O5/c1-29(2,3)25(34)18-33-24-15-8-7-14-23(24)32(21-12-5-4-6-13-21)17-22(26(33)35)31-28(38)30-20-11-9-10-19(16-20)27(36)37/h7-11,14-16,21-22H,4-6,12-13,17-18H2,1-3H3,(H,36,37)(H2,30,31,38)/t22-/m1/s1
InChi Key VIJCCFFEBCOOIE-JOCHJYFZSA-N
Canonical SMILES CC(C)(C)C(=O)CN1C2=CC=CC=C2N(CC(C1=O)NC(=O)NC3=CC=CC(=C3)C(=O)O)C4CCCCC4
Isomeric SMILES CC(C)(C)C(=O)CN1C2=CC=CC=C2N(C[C@H](C1=O)NC(=O)NC3=CC=CC(=C3)C(=O)O)C4CCCCC4
PubChem CID 9872609
Molecular Weight 520.6

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

12 results found

Lot NumberCertificate TypeDateItem
G2416533Certificate of AnalysisApr 01, 2024 N413682
G2416534Certificate of AnalysisApr 01, 2024 N413682
G2416580Certificate of AnalysisApr 01, 2024 N413682
G2416581Certificate of AnalysisApr 01, 2024 N413682
G2416582Certificate of AnalysisApr 01, 2024 N413682
G2416583Certificate of AnalysisApr 01, 2024 N413682
G2416584Certificate of AnalysisApr 01, 2024 N413682
G2416585Certificate of AnalysisApr 01, 2024 N413682
G2416586Certificate of AnalysisApr 01, 2024 N413682
G2416587Certificate of AnalysisApr 01, 2024 N413682
G2416588Certificate of AnalysisApr 01, 2024 N413682
G2416589Certificate of AnalysisApr 01, 2024 N413682

Show more⌵

Chemical and Physical Properties

SolubilityDMSO: 30 mg/mL (57.63 mM)

Related Documents

Solution Calculators