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NCC007 - 98%, high purity , CAS No.2342583-66-6

≥98%

CAS#: 2342583-66-6
Formula: C₂₂H₂₈F₃N₇
Molecular Weight: 447.50
PubChem CID: 138403252

Item Number

N412562

Grouped product items
SKU	Size	Availability	Price
N412562-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$15.90
N412562-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$98.90
N412562-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$99.90
N412562-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$246.90
N412562-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$319.90
N412562-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$489.90

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

NCC007 is a novel dual inhibitor of CKIα and CKIδwith IC50 of 1.8 μM and 3.6 μM, respectively.

Storage Temp

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Associated Targets(Human)

CSNK1D Tchem Casein kinase I delta (4546 Activities)

Discover Target: CSNK1D

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CDK6 Tclin Cyclin-dependent kinase 6 (1724 Activities)

Discover Target: CDK6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CSNK1E Tclin Casein kinase I epsilon (1412 Activities)

Discover Target: CSNK1E

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CDK2 Tchem Cyclin-dependent kinase 2 (9050 Activities)

Discover Target: CDK2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CSNK1A1 Tchem Casein kinase I alpha (2581 Activities)

Discover Target: CSNK1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAPK8 Tchem c-Jun N-terminal kinase 1 (5038 Activities)

Discover Target: MAPK8

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CDK7 Tchem Cyclin-dependent kinase 7 (1512 Activities)

Discover Target: CDK7

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CLK2 Tchem Dual specificity protein kinase CLK2 (3942 Activities)

Discover Target: CLK2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SRPK1 Tchem Serine/threonine-protein kinase SRPK1 (2359 Activities)

Discover Target: SRPK1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CSNK1A1L Tdark Casein kinase I isoform alpha-like (290 Activities)

Discover Target: CSNK1A1L

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SRPK2 Tchem Serine/threonine-protein kinase SRPK2 (719 Activities)

Discover Target: SRPK2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CCNH Tbio CDK7/Cyclin H/MNAT1 (693 Activities)

Discover Target: CCNH

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CSNK1D Tchem Casein kinase I isoform alpha/delta (40 Activities)

Discover Target: CSNK1D

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	9-(1-cyclopropylethyl)-2-N-[2-(dimethylamino)ethyl]-6-N-[[3-(trifluoromethyl)phenyl]methyl]purine-2,6-diamine
INCHI	InChI=1S/C22H28F3N7/c1-14(16-7-8-16)32-13-28-18-19(29-21(30-20(18)32)26-9-10-31(2)3)27-12-15-5-4-6-17(11-15)22(23,24)25/h4-6,11,13-14,16H,7-10,12H2,1-3H3,(H2,26,27,29,30)
InChi Key	GHRNSZVMIARHIS-UHFFFAOYSA-N
Canonical SMILES	CC(C1CC1)N2C=NC3=C(N=C(N=C32)NCCN(C)C)NCC4=CC(=CC=C4)C(F)(F)F
Isomeric SMILES	CC(C1CC1)N2C=NC3=C(N=C(N=C32)NCCN(C)C)NCC4=CC(=CC=C4)C(F)(F)F
PubChem CID	138403252
Molecular Weight	447.50

Certificates

Certificate of Analysis(COA)

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12 results found

Lot Number	Certificate Type	Date	Item
B2402443	Certificate of Analysis	Dec 26, 2023	N412562
B2402444	Certificate of Analysis	Dec 26, 2023	N412562
B2402445	Certificate of Analysis	Dec 26, 2023	N412562
B2402446	Certificate of Analysis	Dec 26, 2023	N412562
B2402457	Certificate of Analysis	Dec 26, 2023	N412562
B2402458	Certificate of Analysis	Dec 26, 2023	N412562
B2402459	Certificate of Analysis	Dec 26, 2023	N412562
B2402460	Certificate of Analysis	Dec 26, 2023	N412562
B2402461	Certificate of Analysis	Dec 26, 2023	N412562
B2402462	Certificate of Analysis	Dec 26, 2023	N412562
B2402463	Certificate of Analysis	Dec 26, 2023	N412562
B2402464	Certificate of Analysis	Dec 26, 2023	N412562

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Safety and Hazards(GHS)

Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection.

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NCC007 - 98%, high purity , CAS No.2342583-66-6

Basic Description

Associated Targets(Human)

Associated Targets(non-human)