NCGC607 - 98%, high purity , CAS No.1462267-07-7, glucosylceramidase beta

Item Number

N412968

Grouped product items
SKU	Size	Availability	Price
N412968-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,691.90
N412968-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,761.90
N412968-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,821.90
N412968-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$319.90
N412968-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,171.90
N412968-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,481.90

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Basic Description

Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	NCGC607 is a a noninhibitory chaperone of glucocerebrosidase (GCase).
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Mechanism of action	glucosylceramidase beta
Product Description	Information NCGC607 is a a noninhibitory chaperone of glucocerebrosidase (GCase).

Names and Identifiers

IUPAC Name	2-[2-(4-iodoanilino)-2-oxoethoxy]-N-[2-(N-methylanilino)-2-oxoethyl]benzamide
INCHI	InChI=1S/C24H22IN3O4/c1-28(19-7-3-2-4-8-19)23(30)15-26-24(31)20-9-5-6-10-21(20)32-16-22(29)27-18-13-11-17(25)12-14-18/h2-14H,15-16H2,1H3,(H,26,31)(H,27,29)
InChi Key	HFVDMJQQAKLUSN-UHFFFAOYSA-N
Canonical SMILES	CN(C1=CC=CC=C1)C(=O)CNC(=O)C2=CC=CC=C2OCC(=O)NC3=CC=C(C=C3)I
Isomeric SMILES	CN(C1=CC=CC=C1)C(=O)CNC(=O)C2=CC=CC=C2OCC(=O)NC3=CC=C(C=C3)I
PubChem CID	46943210
Molecular Weight	543.35

PubChem CID

CAS Registry No.

Certificates

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12 results found

Lot Number	Certificate Type	Date	Item
F2420278	Certificate of Analysis	Mar 14, 2024	N412968
F2420279	Certificate of Analysis	Mar 14, 2024	N412968
F2420280	Certificate of Analysis	Mar 14, 2024	N412968
F2420281	Certificate of Analysis	Mar 14, 2024	N412968
F2420282	Certificate of Analysis	Mar 14, 2024	N412968
F2420283	Certificate of Analysis	Mar 14, 2024	N412968
F2420284	Certificate of Analysis	Mar 14, 2024	N412968
F2420285	Certificate of Analysis	Mar 14, 2024	N412968
F2420286	Certificate of Analysis	Mar 14, 2024	N412968
F2420287	Certificate of Analysis	Mar 14, 2024	N412968
F2420288	Certificate of Analysis	Mar 14, 2024	N412968
F2420289	Certificate of Analysis	Mar 14, 2024	N412968

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References

1. Aflaki E, Borger DK, Moaven N, Stubblefield BK, Rogers SA, Patnaik S, Schoenen FJ, Westbroek W, Zheng W, Sullivan P et al.. (2016) A New Glucocerebrosidase Chaperone Reduces α-Synuclein and Glycolipid Levels in iPSC-Derived Dopaminergic Neurons from Patients with Gaucher Disease and Parkinsonism.. J Neurosci, 36 (28): (7441-52). [PMID:27413154] [10.1021/op500134e]
2. Boland B, Yu WH, Corti O, Mollereau B, Henriques A, Bezard E, Pastores GM, Rubinsztein DC, Nixon RA, Duchen MR et al.. (2018) Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing.. Nat Rev Drug Discov, 17 (9): (660-688). [PMID:30116051] [10.1021/op500134e]

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