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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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N275347-1g | 1g | In stock | $35.90 | |
N275347-5g | 5g | In stock | $135.90 |
Zwitterionic non-detergent sulfobetaine.
Synonyms | Dimethylethylammoniumpropane sulfonate | ETHYL DIMETHYL AMMONIO PROPANE SULFONATE | HY-135484 | SY347253 | 3-(Ethyldimethylammonio)propane-1-sulfonate | NDSB-195 | DIMETHYLETHYL-(3-SULFOPROPYL)AMMONIUM, INNER SALT | Dimethylethyl-(3-sulfopropyl)ammonium,i |
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Specifications & Purity | ≥97% |
Biochemical and Physiological Mechanisms | Zwitterionic non-detergent sulfobetaine. Used to extract, solubilise and crystallise proteins. Prevents protein aggregation and promotes renaturation of denatured proteins. |
Storage Temp | Room temperature,Argon charged |
Shipped In | Normal |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Dimethylethylammoniumpropane sulfonate is a zwitterionic solubilizing agent with usefulness in protein crystallization. Product Application Dimethylethylammoniumpropane sulfonate has been used in a study to assess the functional properties of the separate subunits of the human DNA helicase II/Ku autoantigen. It has also been used in a study to investigate the swelling behaviors of copolymeric hydrogels in various saline solutions. Non-detergent sulfobetaine is a compound used for non-denaturing protien purification. Increases the extraction yield of membrane, nuclear and cytoskeletal associated proteins. Zwitterionic over a wide pH range, easily removed by dialysis and no significant absorption in the near UV range. Specific applications include microsomal protein extraction, nuclear protein recovery, precipitation reduction in IEF, and membrane-bound protease purification. |
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Pubchem Sid | 488195164 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488195164 |
IUPAC Name | 3-[ethyl(dimethyl)azaniumyl]propane-1-sulfonate |
INCHI | InChI=1S/C7H17NO3S/c1-4-8(2,3)6-5-7-12(9,10)11/h4-7H2,1-3H3 |
InChi Key | NNCRHRDBFDCWPA-UHFFFAOYSA-N |
Canonical SMILES | CC[N+](C)(C)CCCS(=O)(=O)[O-] |
Isomeric SMILES | CC[N+](C)(C)CCCS(=O)(=O)[O-] |
PubChem CID | 5221296 |
Molecular Weight | 195.28 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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H2409494 | Certificate of Analysis | Jul 26, 2024 | N275347 |
A2303623 | Certificate of Analysis | Oct 24, 2023 | N275347 |
A2303624 | Certificate of Analysis | Oct 18, 2023 | N275347 |
B2324009 | Certificate of Analysis | Dec 12, 2022 | N275347 |
B2423065 | Certificate of Analysis | Dec 12, 2022 | N275347 |
Solubility | Soluble in water to 100 mM |
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Sensitivity | Moisture sensitive. |
Pictogram(s) | GHS05 |
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Signal | Danger |
Hazard Statements | H314:Causes severe skin burns and eye damage H318:Causes serious eye damage |
Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P363:Wash contaminated clothing before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes. P316:Get emergency medical help immediately. |