NDSB-195 - ≥97%, high purity , CAS No.160255-06-1

  • ≥97%
Item Number
N275347
Grouped product items
SKUSizeAvailabilityPrice Qty
N275347-1g
1g
In stock
$35.90
N275347-5g
5g
In stock
$135.90

Zwitterionic non-detergent sulfobetaine.

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Detergent

Basic Description

SynonymsDimethylethylammoniumpropane sulfonate | ETHYL DIMETHYL AMMONIO PROPANE SULFONATE | HY-135484 | SY347253 | 3-(Ethyldimethylammonio)propane-1-sulfonate | NDSB-195 | DIMETHYLETHYL-(3-SULFOPROPYL)AMMONIUM, INNER SALT | Dimethylethyl-(3-sulfopropyl)ammonium,i
Specifications & Purity≥97%
Biochemical and Physiological MechanismsZwitterionic non-detergent sulfobetaine. Used to extract, solubilise and crystallise proteins. Prevents protein aggregation and promotes renaturation of denatured proteins.
Storage TempRoom temperature,Argon charged
Shipped InNormal
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Dimethylethylammoniumpropane sulfonate is a zwitterionic solubilizing agent with usefulness in protein crystallization.


Product Application

Dimethylethylammoniumpropane sulfonate has been used in a study to assess the functional properties of the separate subunits of the human DNA helicase II/Ku autoantigen. It has also been used in a study to investigate the swelling behaviors of copolymeric hydrogels in various saline solutions.

Non-detergent sulfobetaine is a compound used for non-denaturing protien purification. Increases the extraction yield of membrane, nuclear and cytoskeletal associated proteins. Zwitterionic over a wide pH range, easily removed by dialysis and no significant absorption in the near UV range. Specific applications include microsomal protein extraction, nuclear protein recovery, precipitation reduction in IEF, and membrane-bound protease purification.

Associated Targets(Human)

BBOX1 Tchem Gamma-butyrobetaine dioxygenase (162 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Pubchem Sid488195164
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488195164
IUPAC Name 3-[ethyl(dimethyl)azaniumyl]propane-1-sulfonate
INCHI InChI=1S/C7H17NO3S/c1-4-8(2,3)6-5-7-12(9,10)11/h4-7H2,1-3H3
InChi Key NNCRHRDBFDCWPA-UHFFFAOYSA-N
Canonical SMILES CC[N+](C)(C)CCCS(=O)(=O)[O-]
Isomeric SMILES CC[N+](C)(C)CCCS(=O)(=O)[O-]
PubChem CID 5221296
Molecular Weight 195.28

Certificates

Certificate of Analysis(COA)

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5 results found

Lot NumberCertificate TypeDateItem
H2409494Certificate of AnalysisJul 26, 2024 N275347
A2303623Certificate of AnalysisOct 24, 2023 N275347
A2303624Certificate of AnalysisOct 18, 2023 N275347
B2324009Certificate of AnalysisDec 12, 2022 N275347
B2423065Certificate of AnalysisDec 12, 2022 N275347

Chemical and Physical Properties

SolubilitySoluble in water to 100 mM
SensitivityMoisture sensitive.

Safety and Hazards(GHS)

Pictogram(s) GHS05
Signal Danger
Hazard Statements

H314:Causes severe skin burns and eye damage

H318:Causes serious eye damage

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P363:Wash contaminated clothing before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P317:Get emergency medical help.

P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes.

P316:Get emergency medical help immediately.

Related Documents

Solution Calculators