NE11808 , CAS No.105462-22-4, Inhibitor of farnesyl diphosphate synthase

Item Number
N612203
Grouped product items
SKUSizeAvailabilityPrice Qty
N612203-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$300.90
N612203-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$941.90

Basic Description

Synonyms105462-22-4 | NE11808 | [1-phosphono-2-(pyridin-2-ylamino)ethyl]phosphonic acid | [2-(pyridin-2-ylamino)ethane-1,1-diyl]bis(phosphonic acid) | CHEMBL294192 | {1-phosphono-2-[(pyridin-2-yl)amino]ethyl}phosphonic acid | 2i19 | NE 11808 | GTPL3160 | SCHEMBL7800998 | DTXSID50328
Specifications & PurityMoligand™
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of farnesyl diphosphate synthase

Associated Targets(Human)

FDPS Tclin Farnesyl pyrophosphate synthase (11 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FDPS Tclin Farnesyl diphosphate synthase (1240 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H460 (60772 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SF-268 (49410 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KB (17409 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PBMC (10003 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hydroxyapatite (165 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Entamoeba histolytica (2676 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Dictyostelium discoideum (81 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L929 (3802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPase1 Vacuolar-type proton translocating pyrophosphatase 1 (115 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Farnesyl pyrophosphate synthase (85 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (23 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name {1-phosphono-2-[(pyridin-2-yl)amino]ethyl}phosphonic acid
INCHI InChI=1S/C7H12N2O6P2/c10-16(11,12)7(17(13,14)15)5-9-6-3-1-2-4-8-6/h1-4,7H,5H2,(H,8,9)(H2,10,11,12)(H2,13,14,15)
InChi Key BHVCADPDEFLLGM-UHFFFAOYSA-N
Canonical SMILES OP(=O)(C(P(=O)(O)O)CNc1ccccn1)O
Isomeric SMILES C1=CC=NC(=C1)NCC(P(=O)(O)O)P(=O)(O)O
PubChem CID 406401

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