NEDD8 inhibitor M22 - 98%, high purity , CAS No.864420-54-2

  • ≥98%
Item Number
N412920
Grouped product items
SKUSizeAvailabilityPrice Qty
N412920-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$33.90
N412920-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$134.90
N412920-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$214.90
N412920-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$429.90
N412920-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$686.90
N412920-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,099.90

Basic Description

Specifications & Purity≥98%
Biochemical and Physiological MechanismsM22 NEDD8 inhibitor (M22) is a novel, potent, selective reversible inhibitor of NEDD8 activating enzyme (NAE). M22 inhibits multiple cancer cell lines and induces apoptosis in A549 cells.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

AGS (1999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BXPC-3 (2997 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
K562 (73714 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-OV-3 (52876 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CUL1 Tbio NEDD8/Cullin-1 (16 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 1-benzyl-N-[2-(2,4-dichlorophenyl)ethyl]piperidin-4-amine
INCHI InChI=1S/C20H24Cl2N2/c21-18-7-6-17(20(22)14-18)8-11-23-19-9-12-24(13-10-19)15-16-4-2-1-3-5-16/h1-7,14,19,23H,8-13,15H2
InChi Key WMEXQHGRMWPOEF-UHFFFAOYSA-N
Canonical SMILES C1CN(CCC1NCCC2=C(C=C(C=C2)Cl)Cl)CC3=CC=CC=C3
Isomeric SMILES C1CN(CCC1NCCC2=C(C=C(C=C2)Cl)Cl)CC3=CC=CC=C3
PubChem CID 6456370
Molecular Weight 363.32

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7 results found

Lot NumberCertificate TypeDateItem
A2422138Certificate of AnalysisDec 20, 2023 N412920
A2422139Certificate of AnalysisDec 20, 2023 N412920
A2422140Certificate of AnalysisDec 20, 2023 N412920
A2422141Certificate of AnalysisDec 20, 2023 N412920
A2422142Certificate of AnalysisDec 20, 2023 N412920
A2422143Certificate of AnalysisDec 20, 2023 N412920
A2422144Certificate of AnalysisDec 20, 2023 N412920

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