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Nepafenac - 10mM in DMSO, high purity , CAS No.78281-72-8
Basic Description Synonyms Nepafenac | 78281-72-8 | Nevanac | 2-(2-Amino-3-benzoylphenyl)acetamide | 2-Amino-3-benzoylbenzeneacetamide | Ilevro | AHR-9434 | AL 6515 | AL-6515 | AHR 9434 | Benzeneacetamide, 2-amino-3-benzoyl- | nepafenaco | nepafenacum | CHEBI:75922 | UNII-0J9L7J6V8C | 0J9L7J6V8C | DTXSID0048638 | D Specifications & Purity Moligand™, 10mM in DMSO Biochemical and Physiological Mechanisms Nepafenac is a NSAID (nonsteroidal anti inflammatory drug) that is routinely used in opthamology to control pain following cataract surgery. Nepafenac is a selective COX-2 inhibitor. Nepafenac is prodrug of Amfenac. Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Grade Moligand™ Product Description An analgesic selective inhibitor of COX-2
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name 2-(2-amino-3-benzoylphenyl)acetamide INCHI InChI=1S/C15H14N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8H,9,17H2,(H2,16,18) InChi Key QEFAQIPZVLVERP-UHFFFAOYSA-N Canonical SMILES C1=CC=C(C=C1)C(=O)C2=CC=CC(=C2N)CC(=O)N Isomeric SMILES C1=CC=C(C=C1)C(=O)C2=CC=CC(=C2N)CC(=O)N WGK Germany 3 PubChem CID 151075 Molecular Weight 254.28
Chemical and Physical Properties Sensitivity Heat sensitive Melt Point(°C) 184 °C
Safety and Hazards(GHS) Pictogram(s) GHS09 Signal Warning Hazard Statements H400: Very toxic to aquatic life
Precautionary Statements P273: Avoid release to the environment.
P501: Dispose of contents/container to ...
P391: Collect spillage.
WGK Germany 3 Merck Index 6469
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