Neuropathiazol - ≥98%(HPLC), high purity , CAS No.880090-88-0

  • ≥98%(HPLC)
Item Number
N287361
Grouped product items
SKUSizeAvailabilityPrice Qty
N287361-5mg
5mg
In stock
$79.90
N287361-10mg
10mg
In stock
$121.90
N287361-25mg
25mg
In stock
$273.90
N287361-50mg
50mg
In stock
$509.90

Selective inducer of neuronal differentiation in hippocampal neural progenitors

Basic Description

SynonymsAKOS015919526 | BCPP000150 | Ethyl 4-(methyl(2-phenylthiazol-4-yl)amino)benzoate;Neuropathiazol | SCHEMBL8238620 | BCP02467 | A14058 | DTXSID80470323 | Ethyl 4-(methyl(2-phenylthiazol-4-yl)amino)benzoate | FT-0727742 | HB3105 | Ethyl 4-[methyl-(2-phenyl-1
Specifications & Purity≥98%(HPLC)
Biochemical and Physiological MechanismsSelective inducer of neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs). Selectively suppresses astrocyte differentiation when induced by LIF, BMP2 and FBS compared to retinoic acid. Enhances maturation of NPC derived neurons.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Product description:

Neuropathiazol, a neuronal differentiation inducer, selectively induces neuronal differentiation of multipotent hippocampal neural progenitor cells.


Associated Targets(Human)

HDAC6 Tclin Histone deacetylase 6 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488197653
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488197653
IUPAC Name ethyl 4-[methyl-(2-phenyl-1,3-thiazol-4-yl)amino]benzoate
INCHI InChI=1S/C19H18N2O2S/c1-3-23-19(22)15-9-11-16(12-10-15)21(2)17-13-24-18(20-17)14-7-5-4-6-8-14/h4-13H,3H2,1-2H3
InChi Key MGKYEWWFHSESJN-UHFFFAOYSA-N
Canonical SMILES CCOC(=O)C1=CC=C(C=C1)N(C)C2=CSC(=N2)C3=CC=CC=C3
Isomeric SMILES CCOC(=O)C1=CC=C(C=C1)N(C)C2=CSC(=N2)C3=CC=CC=C3
PubChem CID 11667240
Molecular Weight 338.42

Certificates

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8 results found

Lot NumberCertificate TypeDateItem
D23141887Certificate of AnalysisMar 06, 2023 N287361
D23141910Certificate of AnalysisMar 06, 2023 N287361
D23141917Certificate of AnalysisMar 06, 2023 N287361
D23141928Certificate of AnalysisMar 06, 2023 N287361
D23141929Certificate of AnalysisMar 06, 2023 N287361
D23141930Certificate of AnalysisMar 06, 2023 N287361
D23141938Certificate of AnalysisMar 06, 2023 N287361
D23141955Certificate of AnalysisMar 06, 2023 N287361

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 33.84, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 6.77, Max Conc. mM: 20

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