Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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N129779-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $94.90 | |
N129779-500mg | 500mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $427.90 | |
N129779-1g | 1g | In stock | $769.90 | |
N129779-5g | 5g | In stock | $3,462.90 | |
N129779-25g | 25g | In stock | $15,582.90 | |
N129779-100g | 100g | In stock | $56,096.90 |
Synonyms | HMS3655I08 | HMS3715B10 | MLS001424058 | Nevirapine [USAN:USP:INN:BAN] | Nevirapine) | SCHEMBL3318 | NSC 641530 | 11-cyclopropyl-4-methyl-5H-dipyrido[[?],[?]][1,4]diazepin-6-one | NEVIRAPINE [VANDF] | NEVIRAPINE [WHO-DD] | Viramune (TN) | Viramune IR | AC |
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Specifications & Purity | ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | Nevirapine is a potent (IC50 = 84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase (HIV-1 RT). |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Action Type | INHIBITOR |
Mechanism of action | Human immunodeficiency virus type 1 reverse transcriptase inhibitor |
Note | 1g卖完停产,不再备货 |
Product Description | Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS. |
ALogP | 2 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 2-cyclopropyl-7-methyl-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-10-one |
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INCHI | InChI=1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,18,20) |
InChi Key | NQDJXKOVJZTUJA-UHFFFAOYSA-N |
Canonical SMILES | CC1=C2C(=NC=C1)N(C3=C(C=CC=N3)C(=O)N2)C4CC4 |
Isomeric SMILES | CC1=C2C(=NC=C1)N(C3=C(C=CC=N3)C(=O)N2)C4CC4 |
WGK Germany | 2 |
PubChem CID | 4463 |
Molecular Weight | 266.3 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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G1524089 | Certificate of Analysis | Feb 23, 2024 | N129779 |
C2209184 | Certificate of Analysis | Dec 18, 2023 | N129779 |
K2108723 | Certificate of Analysis | Aug 14, 2023 | N129779 |
F1921241 | Certificate of Analysis | Jan 09, 2023 | N129779 |
J2231134 | Certificate of Analysis | Nov 10, 2022 | N129779 |
Solubility | Soluble in Chloroform and Methanol |
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Sensitivity | Heat sensitive |
Melt Point(°C) | 247-249°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H412:Harmful to aquatic life with long lasting effects H302:Harmful if swallowed |
Precautionary Statements | P273:Avoid release to the environment. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
WGK Germany | 2 |
Merck Index | 6490 |
1. Mingtong Ye, Nengzhi Pang, Ting Wan, Yuanling Huang, Tianyi Wei, Xuye Jiang, Yujia Zhou, Yufeng Huang, Hainan Yang, Zhenfeng Zhang, Lili Yang. (2019) Oxidized Vitamin C (DHA) Overcomes Resistance to EGFR-targeted Therapy of Lung Cancer through Disturbing Energy Homeostasis. Journal of Cancer, 10 (3): ( 757–764). [PMID:30719175] |
2. Mingtong Ye, Sufan Wang, Ting Wan, Rui Jiang, Yun Qiu, Lei Pei, Nengzhi Pang, Yuanling Huang, Yufeng Huang, Zhenfeng Zhang, Lili Yang. (2017) Combined Inhibitions of Glycolysis and AKT/autophagy Can Overcome Resistance to EGFR-targeted Therapy of Lung Cancer. Journal of Cancer, 8 (18): ( 3774–3784). [PMID:29151965] |
1. Mingtong Ye, Nengzhi Pang, Ting Wan, Yuanling Huang, Tianyi Wei, Xuye Jiang, Yujia Zhou, Yufeng Huang, Hainan Yang, Zhenfeng Zhang, Lili Yang. (2019) Oxidized Vitamin C (DHA) Overcomes Resistance to EGFR-targeted Therapy of Lung Cancer through Disturbing Energy Homeostasis. Journal of Cancer, 10 (3): ( 757–764). [PMID:30719175] |
2. Mingtong Ye, Sufan Wang, Ting Wan, Rui Jiang, Yun Qiu, Lei Pei, Nengzhi Pang, Yuanling Huang, Yufeng Huang, Zhenfeng Zhang, Lili Yang. (2017) Combined Inhibitions of Glycolysis and AKT/autophagy Can Overcome Resistance to EGFR-targeted Therapy of Lung Cancer. Journal of Cancer, 8 (18): ( 3774–3784). [PMID:29151965] |