Selective, L-type Ca 2+ channel blocker (IC 50 = 24.1 μM). Dihydropyridine derivative. Potent coronary and cerebral vasodilator.
Storage Temp
Store at 2-8°C
Shipped In
Wet ice
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Nicardipine hydrochloride is the hydrochloride salt preparation of Nicardipine and a potent L-type calcium channel protein inhibitor. Nicardipine is described to alter cytochrome P-450 3A expression through induction of CYP3A. Nicardipine blockade of Ca2+ channels has been correlated to antihypertensive effects. A potent calcium channel protein inhibitor
1.Qinglin Wang, Hao Yuan, Xinyue Pan, Yiling Yang, Xiaosong Ma, Yahui Guo. (2024) Synthesis of silver nanoclusters using a double-stranded DNA template and its application for captopril detection. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 126 (17):(105825). [PMID:17580304][10.1016/j.jfca.2023.105825]
2.Wei Dong, Qin Zhou, Wangqiang Shen, Le Yang, Peng Jin, Xing Lu, Yongfu Lian. (2023) The Various Packing Structures of Tb@C82 (I, II) Isomers in Their Cocrystals with Ni(OEP). Nanomaterials, 13 (6):(994). [PMID:36985888][10.3390/nano13060994]
3.Xin Song, Jiangle An, Chao He, Jukai Zhou, Yuanting Xu, Haifeng Ji, Li Yang, Jiarui Yin, Weifeng Zhao, Changsheng Zhao. (2019) A bioinspired strategy towards super-adsorbent hydrogel spheres via self-sacrificing micro-reactors for robust wastewater remediation. Journal of Materials Chemistry A, 7 (37):(21386-21403). [PMID:][10.1039/C9TA05550A]
4.Sun Fu-Hua, Dong Jinfeng, Tang Huaichao, Zhuang
Hua-Lu, Li Jing-Feng. (2019) ZnO-Nanoparticle-Dispersed Cu11.5Ni0.5Sb4S13−δ Tetrahedrite Composites with Enhanced Thermoelectric Performance. JOURNAL OF ELECTRONIC MATERIALS, 48 (4):(1840-1845). [PMID:][10.1007/s11664-018-06839-3]
References
1.Qinglin Wang, Hao Yuan, Xinyue Pan, Yiling Yang, Xiaosong Ma, Yahui Guo. (2024) Synthesis of silver nanoclusters using a double-stranded DNA template and its application for captopril detection. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 126 (17):(105825). [PMID:17580304][10.1016/j.jfca.2023.105825]
2.Wei Dong, Qin Zhou, Wangqiang Shen, Le Yang, Peng Jin, Xing Lu, Yongfu Lian. (2023) The Various Packing Structures of Tb@C82 (I, II) Isomers in Their Cocrystals with Ni(OEP). Nanomaterials, 13 (6):(994). [PMID:36985888][10.3390/nano13060994]
3.Xin Song, Jiangle An, Chao He, Jukai Zhou, Yuanting Xu, Haifeng Ji, Li Yang, Jiarui Yin, Weifeng Zhao, Changsheng Zhao. (2019) A bioinspired strategy towards super-adsorbent hydrogel spheres via self-sacrificing micro-reactors for robust wastewater remediation. Journal of Materials Chemistry A, 7 (37):(21386-21403). [PMID:][10.1039/C9TA05550A]
4.Sun Fu-Hua, Dong Jinfeng, Tang Huaichao, Zhuang
Hua-Lu, Li Jing-Feng. (2019) ZnO-Nanoparticle-Dispersed Cu11.5Ni0.5Sb4S13−δ Tetrahedrite Composites with Enhanced Thermoelectric Performance. JOURNAL OF ELECTRONIC MATERIALS, 48 (4):(1840-1845). [PMID:][10.1007/s11664-018-06839-3]
Solution Calculators
Molarity Calculator
Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator
Determine the dilution needed to prepare a stock solution.
B1528014