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Niclosamide - 98%, high purity , CAS No.50-65-7

Specifications & Purity:  98%
Item Number
N130841
Grouped product items
SKUSizeAvailabilityPrice Qty
N130841-5g
5g
In stock
$58.90
N130841-25g
25g
In stock
$265.90
N130841-50g
50g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$477.90
N130841-250g
250g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$2,150.90
N130841-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$3,870.90

Antihelminthic, anticancer and protonophric agent. STAT3 inhibitor.

Basic Description

Synonymsniclosamide|50-65-7|5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide|Niclocide|Bayluscid|Phenasal|Cestocid|Devermin|Devermine|Helmiantin|Mansonil|Radeverm|Tredemine|Vermitid|Atenase|Fenasal|Iomesan|Iomezan|Lintex|Nasemo|Sagimid|Sulqui|Yomesan|Mato|F
Specifications & Purity98%
Shipped InNormal

Product Properties

ALogP4

Names and Identifiers

Pubchem Sid488179836
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488179836
IUPAC Name 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
INCHI InChI=1S/C13H8Cl2N2O4/c14-7-1-4-12(18)9(5-7)13(19)16-11-3-2-8(17(20)21)6-10(11)15/h1-6,18H,(H,16,19)
InChi Key RJMUSRYZPJIFPJ-UHFFFAOYSA-N
Canonical SMILES C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O
Isomeric SMILES C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O
WGK Germany 2
RTECS VN8400000
Alternate CAS 50-65-7,1420-04-8,1420-04-8 (2-aminoethanol (1:1))
PubChem CID 4477
NSC Number 178296
UN Number 3077
MeSH Entry Terms Bayer 2353;Bayer 73;Bayluscide;Clonitralide;Fenasal;Niclocide;Niclosamide;Niclosamide, 2-Aminoethanol (1:1);Phenasal;Radewerm;Tr\u00e9d\u00e9mine;Yomesan
Molecular Weight 327.12
Beilstein 2820605

Certificates

Certificate of Analysis(COA)

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5 results found

Lot NumberCertificate TypeDateItem
B2317063Certificate of AnalysisFeb 20, 2023 N130841
I2227509Certificate of AnalysisSep 05, 2022 N130841
I2227523Certificate of AnalysisSep 05, 2022 N130841
I2227524Certificate of AnalysisSep 05, 2022 N130841
I2227527Certificate of AnalysisSep 05, 2022 N130841

Chemical and Physical Properties

SolubilitySoluble in ethanol (25 mM), DMSO (10 mM), chloroform (very slightly), and methanol: acetone (1: 1) (50 mg/ml). Insoluble in water.
Melt Point(°C)225-230°C

Safety and Hazards(GHS)

Pictogram(s) GHS09,GHS07
Signal Warning
Hazard Statements H319,H400,H410
Precautionary Statements P305+P351+P338,P273,P280,P501,P391,P264+P265,P337+P317
WGK Germany 2
RTECS VN8400000

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References

1. Domfeh SA et al..  (2021)  Cryptolepine inhibits hepatocellular carcinoma growth through inhibiting interleukin-6/STAT3 signalling..  BMC Complement Med Ther,  21  (161).  [PMID:34078370]
2. Martinez R et al..  (2022)  Proteomic Changes in the Monolayer and Spheroid Melanoma Cell Models of Acquired Resistance to BRAF and MEK1/2 Inhibitors..  ACS Omega,  (4): (3293-3311).  [PMID:35128241]

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