Determine the necessary mass, volume, or concentration for preparing a solution.
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Synonyms | AI3-18994 | Akotin | Nicagin | Nicotinsaure | Nicovasen | NSC 169454 | SR-01000722017 | BRN 0109591 | Vitaplex N | m-Pyridinecarboxylic acid | Diacin | NAH | Niacin extended release | pellagra | CAS-59-67-6 | Caswell No. 598 | Naotin | nicamin | Nicyl | N |
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Specifications & Purity | Moligand™, analytical standard, ≥99.5%(HPLC) |
Storage Temp | Protected from light |
Shipped In | Normal |
Grade | analytical standard, Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of HCA 1 receptor;Agonist of HCA 2 receptor;Agonist of HCA 3 receptor |
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IUPAC Name | pyridine-3-carboxylic acid |
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INCHI | InChI=1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9) |
InChi Key | PVNIIMVLHYAWGP-UHFFFAOYSA-N |
Canonical SMILES | C1=CC(=CN=C1)C(=O)O |
Isomeric SMILES | C1=CC(=CN=C1)C(=O)O |
RTECS | QT0525000 |
Alternate CAS | 59-67-6,99148-57-9 (tosylate) |
PubChem CID | 938 |
NSC Number | 169454 |
MeSH Entry Terms | 3 Pyridinecarboxylic Acid;3-Pyridinecarboxylic Acid;Aluminum Salt, Niacin;Enduracin;Hydrochloride, Niacin;Induracin;Lithium Nicotinate;Niacin;Niacin Aluminum Salt;Niacin Ammonium Salt;Niacin Calcium Salt;Niacin Cobalt (2+) Salt;Niacin Copper (2+) Salt;Nia |
Molecular Weight | 123.11 |
Beilstein | 109591 |
PubChem CID | 938 |
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DrugBank Ligand | DB00627 |
CAS Registry No. | 59-67-6 |
ChEBI | CHEBI:15940 |
Wikipedia | Niacin |
ChEMBL Ligand | CHEMBL573 |
RCSB PDB Ligand | NIO |
PEP | niacin |
DrugCentral Ligand | 2835 |
GPCRdb Ligand | nicotinic acid |
Enter Lot Number to search for COA:
Sensitivity | Light sensitive. |
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Flash Point(°C) | 193°C |
Melt Point(°C) | 238°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H319:Causes serious eye irritation H412:Harmful to aquatic life with long lasting effects |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to ... P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. |
RTECS | QT0525000 |
Merck Index | 6525 |
1. Yangyang Sun, Zhuzhu Tang, Yanjun Li, Yongkang Song, Hualei Wang, Dongzhi Wei, Shengli Yang. (2024) Identification and evolution of non-traditional nitrilase from Spirosoma linguale DSM 74 with high hydration activity. BIOORGANIC CHEMISTRY, 143 (107055). [PMID:38185008] |
2. Zhi Chen, Zhaohe Dong, Xin Ju, Lishi Yan, Liangzhi Li, Donzhi Wei. (2023) Screening of a novel and thermostable nicotinate dehydrogenase-producing strain Bacillus paramycoides for efficient synthesis of 6-hydroxynicotinic acid. BIOCATALYSIS AND BIOTRANSFORMATION, [PMID:22383884] |
3. Wang Ting, Zhang Jieyuan, Wu Yue, Wang Shiyi, Jiang Xinhui, Zhang Zhengwei, Li Siqiao. (2023) Smartphone-integrated ratiometric fluorescence sensing platform based on bimetallic metal–organic framework nanowires for anthrax biomarker detection. MICROCHIMICA ACTA, 190 (12): (1-9). [PMID:38006440] |
4. Fangfang Li, Yueyue Hu, Yong Cheng, Ying-Hua Zhou. (2024) Design of composite based on UiO-66 and ionic liquid for the CO2 conversion into cyclocarbonate. MICROPOROUS AND MESOPOROUS MATERIALS, 365 (20): (112909). [PMID:20723760] |
5. Zhipeng Wang, Tingting Ma, Junkai Wang, Shaorun Zhu, Mei Zhang, Min Guo. (2023) Surface passivation for efficient and stable perovskite solar cells in ambient air: The structural effect of amine molecules. CERAMICS INTERNATIONAL, [PMID:] |
6. Xinyu Shao, Lulu Cao, Lixia Lu. (2024) Ultrasensitive detection of glucose oxidase and alkaline phosphatase in milk based on valence regulated upconversion nanoprobes. FOOD CHEMISTRY, 432 (137212). [PMID:37634343] |
7. Ning Han, Yifei Li, Haisen Peng, Ruize Gao, Qiongqiong He, Zhenyong Miao, Keji Wan. (2023) Adsorption of Li+ by imprinted capacitor deionization — A new method for selective recovery of valuable lithium in acidic solutions. DESALINATION, 565 (116820). [PMID:] |
8. Yu Yangjian, Liu Peng, Wang Fazhou, Hu Chuanlin. (2023) Preparation of Hydrophobic Fly Ash by Surface Modification and Oil-water Separation Devices. JOURNAL OF WUHAN UNIVERSITY OF TECHNOLOGY-MATERIALS SCIENCE EDITION, 38 (3): (695-700). [PMID:] |
9. Xiao-Dong Cheng, Zheng Zhang, Yun-Ping Li. (2023) A facile approach to undecylenic acid-functionalized stationary phases for per aqueous liquid chromatography. ANALYTICA CHIMICA ACTA, 1265 (341337). [PMID:37230580] |
10. Chao-ping He, Wen-juan Quan, Ya-ling Zeng, Hong-yan Zhou, Pei-dong You, Zhen-xian Li, Ya-mei Li, Li-mei Lin, Bin Liu, Duan-fang Liao, Qin-hui Tuo. (2023) Construction of nicotinic acid curcumin nanoparticles and its Anti-atherosclerosis effect via PCSK9/LDL-R, ABCA1/Caveolin-1/LXR pathway. MATERIALS & DESIGN, 229 (111931). [PMID:] |
11. Zhiyong Zheng, Yuehua Deng, Weining Xie, Sirui Chen, Xiaoxiao Liang, Shiyuan Liu, Yanbin Jiang, Huaiyu Yang. (2023) Co-Former Screening Method for Multicomponent Crystals Based on Partial Least Squares Regression: A Case Study of Ciprofloxacin. CRYSTAL GROWTH & DESIGN, 23 (5): (3244–3257). [PMID:] |
12. Hengye Li, Xingwei Han, Lin Zhang, Wenjie Yu, Wenwen Bie, Meijie Wei, Zhongxia Wang, Fenying Kong, Wei Wang. (2023) Sulfonated polyhedral oligomeric silsesquioxane-cyclodextrin hybrid polymers for efficient removal of micropollutants from water. CARBOHYDRATE POLYMERS, 312 (120832). [PMID:37059548] |
13. Wenlong Wan, Jie Xu, Jiayuan Shi, Xin Zhang, Anran Wang, Xiaojing Dong, Shuyan Miao. (2023) The interaction of dietary niacin and lipid affects the growth, antioxidant capacity and lipid metabolism of male Eriocheir sinensis. Aquaculture Reports, 30 (101541). [PMID:] |
14. Hengye Li, Xingwei Han, Wenjie Yu, Lin Zhang, Wenwen Bie, Meijie Wei, Zhongxia Wang, Fenying Kong, Wei Wang. (2023) Synthesis of porous dimethoxypillar[5]arene knitted β-cyclodextrin copolymers for efficient adsorption of organic micropollutants. CARBOHYDRATE POLYMERS, 310 (120719). [PMID:36925245] |
15. Xue-Jiao Liu, Bao-Di Ma, Xiao-Mei Wu, Yi Xu. (2023) Highly Efficient Biosynthesis of Nicotinic Acid by Immobilized Whole Cells of E. coli Expressing Nitrilase in Semi-Continuous Packed-Bed Bioreactor. Catalysts, 13 (2): (371). [PMID:] |
16. Hongwei Ren, Yize Liu, Ruoyao Zhang, Tengda Zhao, Jing Han, Zhiyang Zheng, Erhong Duan. (2023) Investigation of the CO2 capture behavior in multiple-site natural deep eutectic solvents. PROCESS SAFETY AND ENVIRONMENTAL PROTECTION, 172 (136). [PMID:] |
17. Yujiao Tu, Ze Liu, Lei Jiang, Yingying Xiang, Fei Song, Lifen Meng, Xiuling Ji, Lin Yuan. (2023) Green ratiometric fluorescent dual-mode nanosensor for highly selective and sensitive detection of new coccine in food. DYES AND PIGMENTS, 210 (111024). [PMID:] |
18. Huifang Wu, Mengqi Xu, Yubing Chen, Haoliang Zhang, Yongjun Shen, Yanfeng Tang. (2022) A Highly Sensitive and Selective Nano-Fluorescent Probe for Ratiometric and Visual Detection of Oxytetracycline Benefiting from Dual Roles of Nitrogen-Doped Carbon Dots. Nanomaterials, 12 (23): (4306). [PMID:36500929] |
19. Zhiqin Ding, Mengdie Cai, Weimin Gan, Ping Yuan, Lijun Wei, Xianglei Cheng. (2023) Studies on a novel method for the determination of nitrosamines in food by HPLC-UV-FLD coupling with terbium-doped carbon dots. FOOD CHEMISTRY, 405 (134894). [PMID:] |
20. Lin Yuan, Lei Jiang, Ze Liu, Yingying Xiang, Fei Song, Yujiao Tu. (2023) Selective and sensitive simultaneous detection of tartrazine and Hg2+ based on N-doped yellow-green fluorescent carbon dots. DYES AND PIGMENTS, 209 (110893). [PMID:] |
21. Jinsong Wang, Farzad Seidi, Yang Huang, Huining Xiao. (2022) Smart lignin-based polyurethane conjugated with corrosion inhibitor as bio-based anticorrosive sublayer coating. INDUSTRIAL CROPS AND PRODUCTS, 188 (115719). [PMID:] |
22. Lei Jiang, Lin Yuan, Ze Liu, Yingying Xiang, Fei Song, Lifen Meng, Yujiao Tu. (2022) Facile hydrothermal synthesis and purification of fluorescent carbon dots for food colorant tartrazine detection based on a dual-mode nanosensor. Analytical Methods, 14 (41): (4127-4132). [PMID:36222124] |
23. Yingying Xiang, Yujiao Tu, Lei Jiang, Lin Yuan, Ze Liu, Qiang Xie, Xuequan Xiong, Fei Song. (2022) Orange fluorescent dual-mode nanoprobe for selective and sensitive detection of amaranth based on S,N-Doped carbon dots. DYES AND PIGMENTS, 205 (110533). [PMID:] |
24. Shan Yuan, Miaomiao Jin, Chao Xu, Wencheng Yin, Mingsha Zhao, Mo Xian, Wei Liu. (2022) Self-sufficient whole-cell biocatalysis for 3-(aminomethyl) pyridine synthesis. BIOCHEMICAL ENGINEERING JOURNAL, 183 (108457). [PMID:] |
25. Xiang Yingying, Song Fei, Jiang Lei, Liu Ze, Tu Yujiao. (2022) Novel Fluorescent Nano Carbon Quantum Dots Derived From Lactarius Hatsudake for High Selective Vitamin B12 Detection. JOURNAL OF AOAC INTERNATIONAL, 105 (5): (1350-1359). [PMID:35244160] |
26. Haizhi Zhang, Hongyuan Wu, Xinguang Qin, Ying Shen, Xinlin Wei, Gang Liu. (2022) Metalloporphyrin and gold nanoparticles modified hollow zeolite imidazole Framework-8 with excellent peroxidase like activity for quick colorimetric determination of choline in infant formula milk powder. FOOD CHEMISTRY, 384 (132552). [PMID:35231712] |
27. Zhijun Zhao, Jubao Gao, Mingsheng Luo, Xinyue Liu, Yongsheng Zhao, Weiyang Fei. (2022) Molecular Simulation and Experimental Study on Low-Viscosity Ionic Liquids for High-Efficient Capturing of CO2. ENERGY & FUELS, 36 (3): (1604–1613). [PMID:] |
28. Wang Qiaoying, Cai Jiali, Xu Zihan, Huang Shihui, Zhou Ruiping, Wang Zhiyong. (2022) Albumin-based Theranostic Nanosystem for Drug Controlled Release and Magnetic Resonance Imaging Guided Therapy. Journal of Bionic Engineering, 19 (1): (188-196). [PMID:] |
29. Mengqi Huang, Changlun Tong. (2022) Silicon nanoparticles / gold nanoparticles composite as a fluorescence probe for sensitive and selective detection of Co2+ and vitamin B12 based on the selective aggregation and inner filter effect. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 268 (120706). [PMID:34915228] |
30. Li Qiaofeng, Lan Taijin, He Songhua, Chen Weiwei, Li Xiaolan, Zhang Weiquan, Liu Ying, Zhang Qiuping, Chen Xin, Han Yaoyao, Su Zhiheng, Zhu Dan, Guo Hongwei. (2021) A network pharmacology-based approach to explore the active ingredients and molecular mechanism of Lei-gong-gen formula granule on a spontaneously hypertensive rat model. Chinese Medicine, 16 (1): (1-21). [PMID:34627325] |
31. Xuejia Chen, Tingkai Xiong, Jin Xu, Yan Li, Min Zhang, Ying Liang. (2021) Determination of ammonium in natural water using a quinoline-based o-dialdehyde fluorescent reagent with visible excitation wavelength. Analytical Methods, 13 (43): (5231-5239). [PMID:34704564] |
32. Xiao-Dong Cheng,Yan-Hong Hao,Xi-Tian Peng,Bi-Feng Yuan,Zhi-Guo Shi,Yu-Qi Feng. (2015-05-13) Preparation and chromatographic evaluation of zwitterionic stationary phases with controllable ratio of positively and negatively charged groups.. Talanta, 141 (8-14). [PMID:25966373] |
1. Yangyang Sun, Zhuzhu Tang, Yanjun Li, Yongkang Song, Hualei Wang, Dongzhi Wei, Shengli Yang. (2024) Identification and evolution of non-traditional nitrilase from Spirosoma linguale DSM 74 with high hydration activity. BIOORGANIC CHEMISTRY, 143 (107055). [PMID:38185008] |
2. Zhi Chen, Zhaohe Dong, Xin Ju, Lishi Yan, Liangzhi Li, Donzhi Wei. (2023) Screening of a novel and thermostable nicotinate dehydrogenase-producing strain Bacillus paramycoides for efficient synthesis of 6-hydroxynicotinic acid. BIOCATALYSIS AND BIOTRANSFORMATION, [PMID:22383884] |
3. Wang Ting, Zhang Jieyuan, Wu Yue, Wang Shiyi, Jiang Xinhui, Zhang Zhengwei, Li Siqiao. (2023) Smartphone-integrated ratiometric fluorescence sensing platform based on bimetallic metal–organic framework nanowires for anthrax biomarker detection. MICROCHIMICA ACTA, 190 (12): (1-9). [PMID:38006440] |
4. Fangfang Li, Yueyue Hu, Yong Cheng, Ying-Hua Zhou. (2024) Design of composite based on UiO-66 and ionic liquid for the CO2 conversion into cyclocarbonate. MICROPOROUS AND MESOPOROUS MATERIALS, 365 (20): (112909). [PMID:20723760] |
5. Zhipeng Wang, Tingting Ma, Junkai Wang, Shaorun Zhu, Mei Zhang, Min Guo. (2023) Surface passivation for efficient and stable perovskite solar cells in ambient air: The structural effect of amine molecules. CERAMICS INTERNATIONAL, [PMID:] |
6. Xinyu Shao, Lulu Cao, Lixia Lu. (2024) Ultrasensitive detection of glucose oxidase and alkaline phosphatase in milk based on valence regulated upconversion nanoprobes. FOOD CHEMISTRY, 432 (137212). [PMID:37634343] |
7. Ning Han, Yifei Li, Haisen Peng, Ruize Gao, Qiongqiong He, Zhenyong Miao, Keji Wan. (2023) Adsorption of Li+ by imprinted capacitor deionization — A new method for selective recovery of valuable lithium in acidic solutions. DESALINATION, 565 (116820). [PMID:] |
8. Yu Yangjian, Liu Peng, Wang Fazhou, Hu Chuanlin. (2023) Preparation of Hydrophobic Fly Ash by Surface Modification and Oil-water Separation Devices. JOURNAL OF WUHAN UNIVERSITY OF TECHNOLOGY-MATERIALS SCIENCE EDITION, 38 (3): (695-700). [PMID:] |
9. Xiao-Dong Cheng, Zheng Zhang, Yun-Ping Li. (2023) A facile approach to undecylenic acid-functionalized stationary phases for per aqueous liquid chromatography. ANALYTICA CHIMICA ACTA, 1265 (341337). [PMID:37230580] |
10. Chao-ping He, Wen-juan Quan, Ya-ling Zeng, Hong-yan Zhou, Pei-dong You, Zhen-xian Li, Ya-mei Li, Li-mei Lin, Bin Liu, Duan-fang Liao, Qin-hui Tuo. (2023) Construction of nicotinic acid curcumin nanoparticles and its Anti-atherosclerosis effect via PCSK9/LDL-R, ABCA1/Caveolin-1/LXR pathway. MATERIALS & DESIGN, 229 (111931). [PMID:] |
11. Zhiyong Zheng, Yuehua Deng, Weining Xie, Sirui Chen, Xiaoxiao Liang, Shiyuan Liu, Yanbin Jiang, Huaiyu Yang. (2023) Co-Former Screening Method for Multicomponent Crystals Based on Partial Least Squares Regression: A Case Study of Ciprofloxacin. CRYSTAL GROWTH & DESIGN, 23 (5): (3244–3257). [PMID:] |
12. Hengye Li, Xingwei Han, Lin Zhang, Wenjie Yu, Wenwen Bie, Meijie Wei, Zhongxia Wang, Fenying Kong, Wei Wang. (2023) Sulfonated polyhedral oligomeric silsesquioxane-cyclodextrin hybrid polymers for efficient removal of micropollutants from water. CARBOHYDRATE POLYMERS, 312 (120832). [PMID:37059548] |
13. Wenlong Wan, Jie Xu, Jiayuan Shi, Xin Zhang, Anran Wang, Xiaojing Dong, Shuyan Miao. (2023) The interaction of dietary niacin and lipid affects the growth, antioxidant capacity and lipid metabolism of male Eriocheir sinensis. Aquaculture Reports, 30 (101541). [PMID:] |
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