Nifuroxazide is a nitrofuran compound inhibitor of STAT transcription factor signaling. Nifuroxazide is described to block constitutive phosphorylation of STAT3 by reducing Jak kinase autophosphorylation, decreasing the viability of myeloma cells dependin
Storage Temp
Store at 2-8°C
Shipped In
Wet ice
Grade
Moligand™
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
An inhibitor of STAT activation and signaling activity
1.Cevik UA, Saglik BN, Ozkay Y, Canturk Z, Bueno J, Demirci F, Koparal AS. (2017) Synthesis of New Fluoro-Benzimidazole Derivatives as an Approach towards the Discovery of Novel Intestinal Antiseptic Drug Candidates.. Curr Pharm Des, 23 (15):(2276-2286). [PMID:27908268]
2.Bailly C. (2019) Toward a repositioning of the antibacterial drug nifuroxazide for cancer treatment.. Drug Discov Today, 24 (9):(1930-1936). [PMID:31260646]
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