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Nimbolide - ≥97%, high purity , CAS No.25990-37-8

≥97%

CAS#: 25990-37-8
Formula: C₂₇H₃₀O₇
Molecular Weight: 466.52
PubChem CID: 100017

Item Number

N275747

Grouped product items
SKU	Size	Availability	Price
N275747-1mg	1mg	In stock	$98.90
N275747-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$276.90
N275747-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,018.90

Discover Nimbolide by Aladdin Scientific in ≥97% for only $98.90. Available - in Ligands at Aladdin Scientific. CyclinA and ERK1/2 inhibitor. Terpenoid lactone . Tags: .

Basic Description

Synonyms	Nimbolide\|25990-37-8\|NSC309909\|methyl 2-[6-(furan-3-yl)-7,9,11,15-tetramethyl-12,16-dioxo-3,17-dioxapentacyclo[9.6.1.02,9.04,8.015,18]octadeca-7,13-dien-10-yl]acetate\|Methyl 2-[(1R,2S,4R,6R,9R,10S,11R,15R,18R)-6-(furan-3-yl)-7,9,11,15-tetramethyl-12,16-di
Specifications & Purity	≥97%
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads
Product Description	Nimbolide is a limonoid tetranortriterpenoid with an α,β-unsaturated ketone system and a δ-lactone ring. 添加Biochem/physiol ActionsNimbolide exhibits anti-malarial, anti-bacterial, and anti-cancer activities. It has been shown to induce apoptosis in osteosarcoma cells and inhibits cell migration of these cells by modulating the expression of integrin αvβ5. In human renal carcinoma cells, nimbolide induced cell cycle arrest, DNA damage, and apoptosis. Nimbolide is a triterpene isolated from Azadirachta indica. It has been shown to modulate autophagy and apoptosis in pancreatic cancer.

Names and Identifiers

IUPAC Name	methyl 2-[6-(furan-3-yl)-7,9,11,15-tetramethyl-12,16-dioxo-3,17-dioxapentacyclo[9.6.1.02,9.04,8.015,18]octadeca-7,13-dien-10-yl]acetate
INCHI	InChI=1S/C27H30O7/c1-13-15(14-7-9-32-12-14)10-16-20(13)27(4)17(11-19(29)31-5)26(3)18(28)6-8-25(2)22(26)21(23(27)33-16)34-24(25)30/h6-9,12,15-17,21-23H,10-11H2,1-5H3
InChi Key	JZIQWNPPBKFOPT-UHFFFAOYSA-N
Canonical SMILES	CC1=C2C(CC1C3=COC=C3)OC4C2(C(C5(C6C4OC(=O)C6(C=CC5=O)C)C)CC(=O)OC)C
Isomeric SMILES	CC1=C2C(CC1C3=COC=C3)OC4C2(C(C5(C6C4OC(=O)C6(C=CC5=O)C)C)CC(=O)OC)C
PubChem CID	100017
Molecular Weight	466.52

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4 results found

Lot Number	Certificate Type	Date	Item
K2309104	Certificate of Analysis	May 11, 2023	N275747
J2127320	Certificate of Analysis	Aug 12, 2022	N275747
J2127326	Certificate of Analysis	Aug 12, 2022	N275747
J2127553	Certificate of Analysis	Aug 12, 2022	N275747

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed
Precautionary Statements	P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help.

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