Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | NITRILO-N,N,N-TRIACETIC ACID | Nitrilotriaceticacid | nitrilotriacetic-acid | CCRIS 436 | EINECS 256-488-2 | Nitrilo-2,2''-triacetic acid | Nitrilo-2,2',2''-triacetic acid | Nitrilotriacetic acid, United States Pharmacopeia (USP) Reference Standard | Z104 |
|---|---|
| Specifications & Purity | AR, ≥98.5% |
| Shipped In | Normal |
| Grade | AR |
Associated Targets(Human)
NR3C1 Tclin Glucocorticoid receptor (0 Activities)
CBX1 Tbio Chromobox protein homolog 1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
GMNN Tbio Geminin (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
PTH1R Tclin Parathyroid hormone/parathyroid hormone-related peptide receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
TSHR Tclin Thyrotropin receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
POLI Tchem DNA polymerase iota (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
PLK1 Tchem Serine/threonine-protein kinase PLK1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
NR1I2 Tchem Nuclear receptor subfamily 1 group I member 2 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
THRB Tclin Thyroid hormone receptor beta (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
KDM4A Tchem Lysine-specific demethylase 4A (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PTH1R Tclin Parathyroid hormone receptor (47172 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PLK1 Tchem Serine/threonine-protein kinase PLK1 (28605 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
POLI Tchem DNA polymerase iota (116820 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
GMNN Tbio Geminin (128009 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Associated Targets(non-human)
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
NS1 Nonstructural protein 1 (33327 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| IUPAC Name | 2-[bis(carboxymethyl)amino]acetic acid |
|---|---|
| INCHI | InChI=1S/C6H9NO6/c8-4(9)1-7(2-5(10)11)3-6(12)13/h1-3H2,(H,8,9)(H,10,11)(H,12,13) |
| InChi Key | MGFYIUFZLHCRTH-UHFFFAOYSA-N |
| Canonical SMILES | C(C(=O)O)N(CC(=O)O)CC(=O)O |
| Isomeric SMILES | C(C(=O)O)N(CC(=O)O)CC(=O)O |
| WGK Germany | 2 |
| RTECS | AJ0175000 |
| PubChem CID | 8758 |
| Molecular Weight | 191.14 |
| Beilstein | 1710776 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 J2416633 | Certificate of Analysis | Oct 18, 2024 | N100382 |
| J2416637 | Certificate of Analysis | Oct 18, 2024 | N100382 |
| J2416638 | Certificate of Analysis | Oct 18, 2024 | N100382 |
| D2428409 | Certificate of Analysis | May 08, 2024 | N100382 |
| D2428410 | Certificate of Analysis | May 08, 2024 | N100382 |
| D2428411 | Certificate of Analysis | May 08, 2024 | N100382 |
| I2315232 | Certificate of Analysis | Sep 20, 2023 | N100382 |
| I2315233 | Certificate of Analysis | Sep 20, 2023 | N100382 |
| F23171075 | Certificate of Analysis | Jun 21, 2023 | N100382 |
| F23171080 | Certificate of Analysis | Jun 21, 2023 | N100382 |
| F23171091 | Certificate of Analysis | Jun 21, 2023 | N100382 |
| L2301110 | Certificate of Analysis | Jun 21, 2023 | N100382 |
| C23031150 | Certificate of Analysis | Mar 07, 2023 | N100382 |
| C23031151 | Certificate of Analysis | Mar 07, 2023 | N100382 |
| C2303958 | Certificate of Analysis | Mar 07, 2023 | N100382 |
| F2209159 | Certificate of Analysis | Jul 12, 2022 | N100382 |
Show more⌵
Chemical and Physical Properties
| Solubility | Solubility in water: Practically Insoluble; Degree of Solubility in water: 1.28 g/l 22.5 °C; Soluble in Solution of sodium hydroxide in water,Ethanol |
|---|---|
| Sensitivity | Moisture sensitive. |
| Flash Point(°F) | 212.0 °F |
| Flash Point(°C) | 100 °C |
| Melt Point(°C) | 245°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS08, GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H319:Causes serious eye irritation H351:Suspected of causing cancer H302:Harmful if swallowed |
| Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. |
| WGK Germany | 2 |
| RTECS | AJ0175000 |
| Merck Index | 6579 |
Related Documents
Citations of This Product
| 1. Ting Chen, Pengfei Liu, Tianxiao Liu, Xueyuan Li, Huihui Wang, Tingwei He, Zhiyong Liu. (2024) Three birds with one stone: Nitrilotriacetic acid interface anchoring helps prepare efficient and stable perovskite solar cells. CURRENT APPLIED PHYSICS, 58 (19): (28). [PMID:12815422] [10.1016/j.cap.2023.11.014] |
| 2. Suwei Xia, Qixing Zhou, Ruoxu Sun, Lizhang Chen, Mingyi Zhang, Huan Pang, Lin Xu, Jun Yang, Yawen Tang. (2023) In-situ immobilization of CoNi nanoparticles into N-doped carbon nanotubes/nanowire-coupled superstructures as an efficient Mott-Schottky electrocatalyst toward electrocatalytic oxygen reduction. CHINESE JOURNAL OF CATALYSIS, 54 (3): (278). [PMID:25732826] [10.1016/S1872-2067(23)64545-0] |
| 3. Ying Liao, Yue Pan, Xiang Feng, Xiaobo Chen, Yibin Liu, Chaohe Yang, Hao Yan. (2024) Defective Auδ−-Ov interfacial sites boost C-H bond activation for enhanced selective oxidation of amino alcohols to amino acids. JOURNAL OF CATALYSIS, 429 (115284). [PMID:] [10.1016/j.jcat.2023.115284] |
| 4. Yiqing Liu, Ting Wang, Zhengjie Chen, Shenglan Liu, Yongsheng Fu. (2024) Enhanced removal of sulfamethoxazole by Mn(II)/bisulfite in presence of nitrilotriacetic acid: Role of Mn(III). Journal of Environmental Chemical Engineering, 12 (111821). [PMID:] [10.1016/j.jece.2023.111821] |
| 5. Ruiqi Xie, Zhihui Zhao, Xun Wang, Xiong Tong, Xian Xie. (2023) Flotation separation of scheelite from fluorite by new depressant nitrilotriacetic acid and its mechanism. Journal of the Taiwan Institute of Chemical Engineers, 152 (15): (105153). [PMID:19342671] [10.1016/j.jtice.2023.105153] |
| 6. Lijing Wang, Tianyi Yang, Xiangyu Xu, Guangya Zhang, Yunming Liu, Amin Ju, Gang Zhou, Bo Feng, Guangbo Che, Zhao Zhao. (2023) Acid groups decorated bimetal-organic catalyst for advanced oxidation technology at full pH range. JOURNAL OF ALLOYS AND COMPOUNDS, 969 (13): (172370). [PMID:12670957] [10.1016/j.jallcom.2023.172370] |
| 7. Zhenye Liang, Chao Li, Daxian Zuo, Lin Zeng, Tong Ling, Jiajia Han, Jiayu Wan. (2023) Achieving stable Zn metal anode through novel interface design with multifunctional electrolyte additive. Energy Storage Materials, 63 (102980). [PMID:20547752] [10.1016/j.ensm.2023.102980] |
| 8. Yang Zong, Hua Zhang, Hao Liu, Jun Xu, Zhengwei Zhou, Xiaomeng Zhang, Ting Zhang, Deli Wu. (2023) Selective abatement of electron-rich organic contaminants by trace complexed Mn(II)-catalyzed periodate via high-valent manganese–oxo species. JOURNAL OF HAZARDOUS MATERIALS, 460 (132447). [PMID:37677971] [10.1016/j.jhazmat.2023.132447] |
| 9. Xuefeng Zhang, Yujie Zhang, Qin Yang, Yingchun Yang, Xuping Sun. (2023) MnFe2O4 nanoparticles coated on one-dimensional carbon nanowires derived from Nitrilotriacetic acid as efficient catalysts to activate peroxymonosulfate for moxifloxacin degradation. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 127 (161). [PMID:] [10.1016/j.jiec.2023.07.002] |
| 10. Dingxi Zhang, Yuping Xiang, Guangliang Liu, Lina Liang, Lufeng Chen, Jianbo Shi, Yongguang Yin, Yong Cai, Guibin Jiang. (2023) Mechanism and controlling factors on rapid methylmercury degradation by ligand-enhanced Fenton-like reaction at circumneutral pH. CHEMOSPHERE, 324 (138291). [PMID:36870614] [10.1016/j.chemosphere.2023.138291] |
| 11. Xiaohong Zhou, Wenfeng Zhou, Wei Zhuang, Chenjie Zhu, Hanjie Ying, Hongman Zhang. (2023) Enhanced production of cytidine 5′-monophosphate using biocatalysis of di-enzymes immobilized on amino-functionalized sepharose. CHINESE JOURNAL OF CHEMICAL ENGINEERING, 58 (40). [PMID:] [10.1016/j.cjche.2022.11.002] |
| 12. Ruoyun Lin, Fangjie Lv, Hao Zhang, Yang Li, Jiangang Lu, Jiansheng Li. (2023) Synergizing Fenton oxidation and in-situ coagulation over a wide pH range for the simultaneous removal of multiple pollutants. CHEMICAL ENGINEERING JOURNAL, 454 (140340). [PMID:] [10.1016/j.cej.2022.140340] |
| 13. Yue Zhang, Tiancun Liu, Yaling Ji, Jianhua You, Chen Cai, Yi Wen, Zhujun Yao, Yefeng Yang. (2022) Improved Interface Stability and Zinc-Ions Distribution Achieved by Functional Protective Layer Containing Abundant Oxygen Sites and Regular Channels for Long-Life Zinc-Metal Anodes. Batteries & Supercaps, 5 (11): (e202200335). [PMID:] [10.1002/batt.202200335] |
| 14. Yan Xiao, Liangliang Xiong, Yin Xu, Hui Zhang. (2022) Elimination of bisphenol A with visible light-enhanced peroxydisulfate activation process mediated by Fe3+-nitrilotriacetic acid complex. JOURNAL OF HAZARDOUS MATERIALS, 440 (129780). [PMID:36027750] [10.1016/j.jhazmat.2022.129780] |
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| 20. Kai Liu, Fangbai Li, Yan Pang, Liping Fang, Rosalie Hocking. (2022) Electron shuttle-induced oxidative transformation of arsenite on the surface of goethite and underlying mechanisms. JOURNAL OF HAZARDOUS MATERIALS, 425 (127780). [PMID:34801297] [10.1016/j.jhazmat.2021.127780] |
| 21. Ningning Cao, Songtao Lu, Yuan Yao, Chenxi Liu, Peng Zhang, Qiyang Xiong, Yang Li, Xiaohong Wu. (2022) High-rate long-lasting solar desalination towards hypersaline brine enabled by introducing a siphon-drop mode. CHEMICAL ENGINEERING JOURNAL, 430 (133043). [PMID:] [10.1016/j.cej.2021.133043] |
| 22. Yaqian Dong, Yaohui Zhang, Nana Wang, Guifu Zou, Qiang Zhang, Shengquan Gan, Liang He, Zhongchao Bai. (2021) Pod-Like Fe7S8@N−C Nanowires for High Performance Sodium Ion Batteries. Batteries & Supercaps, 5 (1): (e202100203). [PMID:] [10.1002/batt.202100203] |
| 23. Zhaoqian Yan, Zhihao Sun, Anran Li, Hongshou Liu, Zihao Guo, Lanling Zhao, Jinkui Feng, Lei Qian. (2022) Vacancy and architecture engineering of porous FeP nanorods for achieving superior Li+ storage. CHEMICAL ENGINEERING JOURNAL, 429 (132249). [PMID:] [10.1016/j.cej.2021.132249] |
| 24. Zhaozhao Zhu, Zhao Li, Xinxin Wei, Junjie Wang, Shuhao Xiao, Rong Li, Rui Wu, Jun Song Chen. (2021) Achieving efficient electroreduction of CO2 to CO in a wide potential window by encapsulating Ni nanoparticles in N-doped carbon nanotubes. CARBON, 185 (9). [PMID:] [10.1016/j.carbon.2021.08.072] |
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| 26. Wendi Han, Chenfang Miao, Xintian Zhang, Yinning Lin, Xiaoli Hao, Zhengjun Huang, Shaohuang Weng, Xinhua Lin, Xianzhong Guo, Jianyong Huang. (2021) A signal-off fluorescent strategy for deferasirox effective detection using carbon dots as probe and Cu2+ as medium. ANALYTICA CHIMICA ACTA, 1179 (338853). [PMID:34535261] [10.1016/j.aca.2021.338853] |
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| 37. Yuanqing Huang, Chunping Yang, Zhichao Sun, Guangming Zeng, Huijun He. (2015) Removal of cadmium and lead from aqueous solutions using nitrilotriacetic acid anhydride modified ligno-cellulosic material. RSC Advances, 5 (15): (11475-11484). [PMID:] [10.1039/C4RA14859B] |
| 38. Dian Li, Yu-Ting Zhang, Meng Yu, Jia Guo, Deeptangshu Chaudhary, Chang-Chun Wang. (2013) Cancer therapy and fluorescence imaging using the active release of doxorubicin from MSPs/Ni-LDH folate targeting nanoparticles. BIOMATERIALS, 34 (7913). [PMID:23886730] [10.1016/j.biomaterials.2013.06.046] |
| 39. Yongjian Niu,Chunhua Zhang,Yuanyuan Wang,Dong Fang,Linlin Zhang,Cheng Wang. (2021-01-20) Confining Chainmail-Bearing Ni Nanoparticles in N-doped Carbon Nanotubes for Robust and Efficient Electroreduction of CO2.. ChemSusChem, 14 ((4)): (1140-1154). [PMID:33464697] |
References
| 1. Ting Chen, Pengfei Liu, Tianxiao Liu, Xueyuan Li, Huihui Wang, Tingwei He, Zhiyong Liu. (2024) Three birds with one stone: Nitrilotriacetic acid interface anchoring helps prepare efficient and stable perovskite solar cells. CURRENT APPLIED PHYSICS, 58 (19): (28). [PMID:12815422] [10.1016/j.cap.2023.11.014] |
| 2. Suwei Xia, Qixing Zhou, Ruoxu Sun, Lizhang Chen, Mingyi Zhang, Huan Pang, Lin Xu, Jun Yang, Yawen Tang. (2023) In-situ immobilization of CoNi nanoparticles into N-doped carbon nanotubes/nanowire-coupled superstructures as an efficient Mott-Schottky electrocatalyst toward electrocatalytic oxygen reduction. CHINESE JOURNAL OF CATALYSIS, 54 (3): (278). [PMID:25732826] [10.1016/S1872-2067(23)64545-0] |
| 3. Ying Liao, Yue Pan, Xiang Feng, Xiaobo Chen, Yibin Liu, Chaohe Yang, Hao Yan. (2024) Defective Auδ−-Ov interfacial sites boost C-H bond activation for enhanced selective oxidation of amino alcohols to amino acids. JOURNAL OF CATALYSIS, 429 (115284). [PMID:] [10.1016/j.jcat.2023.115284] |
| 4. Yiqing Liu, Ting Wang, Zhengjie Chen, Shenglan Liu, Yongsheng Fu. (2024) Enhanced removal of sulfamethoxazole by Mn(II)/bisulfite in presence of nitrilotriacetic acid: Role of Mn(III). Journal of Environmental Chemical Engineering, 12 (111821). [PMID:] [10.1016/j.jece.2023.111821] |
| 5. Ruiqi Xie, Zhihui Zhao, Xun Wang, Xiong Tong, Xian Xie. (2023) Flotation separation of scheelite from fluorite by new depressant nitrilotriacetic acid and its mechanism. Journal of the Taiwan Institute of Chemical Engineers, 152 (15): (105153). [PMID:19342671] [10.1016/j.jtice.2023.105153] |
| 6. Lijing Wang, Tianyi Yang, Xiangyu Xu, Guangya Zhang, Yunming Liu, Amin Ju, Gang Zhou, Bo Feng, Guangbo Che, Zhao Zhao. (2023) Acid groups decorated bimetal-organic catalyst for advanced oxidation technology at full pH range. JOURNAL OF ALLOYS AND COMPOUNDS, 969 (13): (172370). [PMID:12670957] [10.1016/j.jallcom.2023.172370] |
| 7. Zhenye Liang, Chao Li, Daxian Zuo, Lin Zeng, Tong Ling, Jiajia Han, Jiayu Wan. (2023) Achieving stable Zn metal anode through novel interface design with multifunctional electrolyte additive. Energy Storage Materials, 63 (102980). [PMID:20547752] [10.1016/j.ensm.2023.102980] |
| 8. Yang Zong, Hua Zhang, Hao Liu, Jun Xu, Zhengwei Zhou, Xiaomeng Zhang, Ting Zhang, Deli Wu. (2023) Selective abatement of electron-rich organic contaminants by trace complexed Mn(II)-catalyzed periodate via high-valent manganese–oxo species. JOURNAL OF HAZARDOUS MATERIALS, 460 (132447). [PMID:37677971] [10.1016/j.jhazmat.2023.132447] |
| 9. Xuefeng Zhang, Yujie Zhang, Qin Yang, Yingchun Yang, Xuping Sun. (2023) MnFe2O4 nanoparticles coated on one-dimensional carbon nanowires derived from Nitrilotriacetic acid as efficient catalysts to activate peroxymonosulfate for moxifloxacin degradation. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 127 (161). [PMID:] [10.1016/j.jiec.2023.07.002] |
| 10. Dingxi Zhang, Yuping Xiang, Guangliang Liu, Lina Liang, Lufeng Chen, Jianbo Shi, Yongguang Yin, Yong Cai, Guibin Jiang. (2023) Mechanism and controlling factors on rapid methylmercury degradation by ligand-enhanced Fenton-like reaction at circumneutral pH. CHEMOSPHERE, 324 (138291). [PMID:36870614] [10.1016/j.chemosphere.2023.138291] |
| 11. Xiaohong Zhou, Wenfeng Zhou, Wei Zhuang, Chenjie Zhu, Hanjie Ying, Hongman Zhang. (2023) Enhanced production of cytidine 5′-monophosphate using biocatalysis of di-enzymes immobilized on amino-functionalized sepharose. CHINESE JOURNAL OF CHEMICAL ENGINEERING, 58 (40). [PMID:] [10.1016/j.cjche.2022.11.002] |
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