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SKU | Size | Availability | Price | Qty |
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N276566-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $309.90 |
Excitotoxic amino acid. 1 ml water soluble pack.
Synonyms | N-methyl-D-aspartic acid | NMDA | 6384-92-5 | N-Methylaspartate | N-Methyl-D-aspartate | D-Aspartic acid, N-methyl- | Methyl aspartic acid | (R)-2-(Methylamino)succinic acid | n-methyl-d-aspartic acid (nmda) | (2R)-2-(methylamino)butanedioic acid | N-Methyl aspartic acid | (R) |
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Specifications & Purity | Moligand™, 100mmol/L in H2O |
Biochemical and Physiological Mechanisms | Excitotoxic amino acid. Prototypic agonist at the ionotropic NMDA glutamate receptor which is involved in long-term potentiation, ischemia, and epilepsy. Soluble in 1 ml water to give specified mM/ml concentration. Find out more. |
Storage Temp | Store at 2-8°C,Desiccated |
Shipped In | Wet ice |
Grade | Moligand™ |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
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IUPAC Name | (2R)-2-(methylamino)butanedioic acid |
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INCHI | InChI=1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/t3-/m1/s1 |
InChi Key | HOKKHZGPKSLGJE-GSVOUGTGSA-N |
Canonical SMILES | CNC(CC(=O)O)C(=O)O |
Isomeric SMILES | CN[C@H](CC(=O)O)C(=O)O |
RTECS | CI9457000 |
PubChem CID | 22880 |
Molecular Weight | 147.13 |
Beilstein | 1724431 |
Reaxy-Rn | 1724431 |
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Solubility | Soluble in 1ml of water to give specified mM/ml concentration |
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Specific Rotation[α] | -15° (C=2,H2O) |
Melt Point(°C) | 178 °C |
RTECS | CI9457000 |
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Reaxy-Rn | 1724431 |
Merck Index | 6662 |
1. Ting Ma, Xiaoxuan Wang, Ting Yu, Juan Liu, Zheqiong Yang, Jinlei Xi. (2023) Oxytetracycline changes the behavior of zebrafish larvae by inhibiting NMDA receptors. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 262 (115344). [PMID:37567108] |
2. Meixi He, Yi Wang, Xiaozhe Zhang, Lihua Zhang. (2023) Exploration of the potential neuroprotective compounds targeting GluN1-GluN2B NMDA receptors. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, [PMID:36591642] |
3. Meixi He, Yingang Feng, Yi Wang, Mengchun Cheng, Xiaozhe Zhang, Lihua Zhang. (2022) Discovery of a cysteine-rich peptide with glycation modification from Achyranthes bidentata Blume. FITOTERAPIA, 163 (105338). [PMID:36270560] |
1. Ting Ma, Xiaoxuan Wang, Ting Yu, Juan Liu, Zheqiong Yang, Jinlei Xi. (2023) Oxytetracycline changes the behavior of zebrafish larvae by inhibiting NMDA receptors. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 262 (115344). [PMID:37567108] |
2. Meixi He, Yi Wang, Xiaozhe Zhang, Lihua Zhang. (2023) Exploration of the potential neuroprotective compounds targeting GluN1-GluN2B NMDA receptors. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, [PMID:36591642] |
3. Meixi He, Yingang Feng, Yi Wang, Mengchun Cheng, Xiaozhe Zhang, Lihua Zhang. (2022) Discovery of a cysteine-rich peptide with glycation modification from Achyranthes bidentata Blume. FITOTERAPIA, 163 (105338). [PMID:36270560] |