Call +1 (833) 552-7181 or Contact us Earn $25 in coupons on your first order with Aladdin!
Toggle Nav
My Cart
Search
Advanced Search
Menu
Sign In
྾
main product photo

NNGH - ≥98%, high purity , CAS No.161314-17-6

  • ≥98%
Item Number
N275540
Grouped product items
SKUSizeAvailabilityPrice Qty
N275540-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
N275540-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$139.90
N275540-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$239.90
N275540-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$489.90
N275540-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$799.90
Add to Wish List Compare
Bulk Order  SDS  DATASHEET

Broad spectrum MMP inhibitor

View related series
Metabolic Enzyme/Protease MMP

Basic Description

SynonymsN-hydroxy-2-[(4-methoxybenzene)(2-methylpropyl)sulfonamido]acetamide | AKOS040744915 | 9P3H27MP46 | mmp-3 inhibitor ii | 2-((4-Methoxyphenyl)sulfonyl-(2-methylpropyl)amino)-N-oxidanyl-ethanamide | CS-0077845 | N-hydroxy-N~2~-[(4-methoxyphenyl)sulfonyl]-N~
Specifications & Purity≥98%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

NNGH is a stromelysin-1 (MMP-3) inhibitor. MMP-3 is both a direct transcriptional target and a necessary contributor of the Wnt/β-catenin signaling pathway. Matrix metalloproteinases (MMPs) play a well-defined role in later stages of tumor progression

Associated Targets(Human)

MMP1 Tchem Interstitial collagenase (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP13 Tchem Collagenase 3 (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP14 Tchem Matrix metalloproteinase-14 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP9 Tchem Matrix metalloproteinase-9 (5 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP12 Tchem Macrophage metalloelastase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP2 Tchem 72 kDa type IV collagenase (7 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP3 Tchem Stromelysin-1 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP8 Tchem Neutrophil collagenase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name N-hydroxy-2-[(4-methoxyphenyl)sulfonyl-(2-methylpropyl)amino]acetamide
INCHI InChI=1S/C13H20N2O5S/c1-10(2)8-15(9-13(16)14-17)21(18,19)12-6-4-11(20-3)5-7-12/h4-7,10,17H,8-9H2,1-3H3,(H,14,16)
InChi Key JIRXORZYIXSWOB-UHFFFAOYSA-N
Canonical SMILES CC(C)CN(CC(=O)NO)S(=O)(=O)C1=CC=C(C=C1)OC
Isomeric SMILES CC(C)CN(CC(=O)NO)S(=O)(=O)C1=CC=C(C=C1)OC
PubChem CID 448002
Molecular Weight 316.37

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeDateItem
H2419527Certificate of AnalysisAug 02, 2024 N275540
H2419528Certificate of AnalysisAug 02, 2024 N275540
H2419529Certificate of AnalysisAug 02, 2024 N275540
H2419530Certificate of AnalysisAug 02, 2024 N275540
H2419531Certificate of AnalysisAug 02, 2024 N275540
H2419536Certificate of AnalysisAug 02, 2024 N275540
H2419537Certificate of AnalysisAug 02, 2024 N275540
H2419538Certificate of AnalysisAug 02, 2024 N275540
H2419545Certificate of AnalysisAug 02, 2024 N275540
H2419546Certificate of AnalysisAug 02, 2024 N275540

Chemical and Physical Properties

SolubilitySoluble in DMSO to 100 mM and in ethanol to 25 mM
SensitivityMoisture sensitive.

Related Documents

 SDS

 Specification Sheet

References

1. Liang M et al..  (2021)  Targeting matrix metalloproteinase MMP3 greatly enhances oncolytic virus mediated tumor therapy..  Transl Oncol,  14  (12): (101221).  [PMID:34530193]

Solution Calculators

Privacy Policy Website Terms of Use Return policy Terms and Conditions of Sale Cookie Policy Sales Policy
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Copyright © 2023-present Aladdin Scientific Corp . All rights reserved.