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Nω-Hydroxy-nor-L-Arginine Dihydrochloride - ≥97%, high purity , CAS No.291758-32-2

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Nω-Hydroxy-nor-L-Arginine Dihydrochloride - ≥97%, high purity , CAS No.291758-32-2

Moligand™

≥97%

CAS#: 291758-32-2
Formula: C₅H₁₄Cl₂N₄O₃
Molecular Weight: 249.1
PubChem CID: 446124

Item Number

N351768

Grouped product items
SKU	Size	Availability	Price	Qty
N351768-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$266.90

a competitive and reversible inhibitor of arginase

Basic Description

Synonyms	(2S)-2-Amino-4-(((hydroxyamino)iminomethyl)amino)butanoic acid \| (2S)-2-amino-4-[(E)-2-hydroxycarbamimidamido]butanoic acid \| N.OMEGA.-HYDROXY-NOR-L-ARGININE \| CHEBI:191070 \| F0001-2381 \| J842.499C \| Q27088086 \| Butanoic acid,2-amino-4-[[(hydroxyamino)imi
Specifications & Purity	≥97%
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Product Description	Competitive, reversible inhibitor of arginase. Neither a substrate nor an inhibitor for iNOS and useful for studying interplays between arginase and NOS. More potent than NOHA and homo-NOHA.

Associated Targets(Human)

ARG2 Tchem Arginase-2, mitochondrial (2 Activities)

Discover Target: ARG2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ARG1 Tchem Arginase-1 (2 Activities)

Discover Target: ARG1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ARG2 Tchem Arginase-2, mitochondrial (9289 Activities)

Discover Target: ARG2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Rattus norvegicus (775804 Activities)

Discover Target:

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ARG1 Arginase-1 (70 Activities)

Discover Target: ARG1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	(2S)-2-amino-4-[[amino-(hydroxyamino)methylidene]amino]butanoic acid
INCHI	InChI=1S/C5H12N4O3/c6-3(4(10)11)1-2-8-5(7)9-12/h3,12H,1-2,6H2,(H,10,11)(H3,7,8,9)/t3-/m0/s1
InChi Key	KOBHCUDVWOTEKO-VKHMYHEASA-N
Canonical SMILES	C(CN=C(N)NO)C(C(=O)O)N
Isomeric SMILES	C(CN=C(N)NO)[C@@H](C(=O)O)N
PubChem CID	446124
Molecular Weight	249.1

Database links

PubChem CID	446124
DrugBank Ligand	DB02381
CAS Registry No.	291758-32-2
ChEMBL Ligand	CHEMBL1234777
RCSB PDB Ligand	NNH

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Refractive Index	n20D~1.62 (Predicted)
Specific Rotation[α]	α24D+14°±2°, c = 1 in 80% acetic acid

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