Click Here for 5% Off Your First Aladdin Purchase!

Nω-Nitro-L-arginine methyl ester hydrochloride - 10mM in Water, high purity , CAS No.51298-62-5

  • 10mM in Water
Item Number
N424409
Grouped product items
SKUSizeAvailabilityPrice Qty
N424409-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$50.90

NOS inhibitor

Basic Description

Synonyms51298-62-5|L-NAME hydrochloride|H-Arg(NO2)-OMe.HCl|LNAME hydrochloride|H-Arg(NO2)-Ome HCl|L-NAME HCl|Methyl N5-(imino(nitroamino)methyl)-L-ornithine monohydrochloride|NG-Nitro-L-arginine methyl ester hydrochloride|L-NAME (hydrochloride)|(S)-Methyl 2-amino
Specifications & Purity10mM in Water
Biochemical and Physiological MechanismsAn analog of arginine that inhibits NO production. It has multiple effects on the vascular system. Inhibits relaxation induced by acetylcholine and induces an increase in arterial blood pressure. Abolishes lecithinized superoxide dismutase induced vasodil
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

Nω-Nitro-L-arginine methyl ester hydrochloride has been used:

• to study the effects of brain-derived neurotrophic factor against neurotoxicity in rat cortical neurons

• to study its effect on far-infrared (FIR) enhanced microcirculation of rat skin

• to study its effect on leptin-induced regulation of myokine fibronectin type III domain containing five/irisin in murine myocytes and fat cells

• to study its effect on the levels of arginine Vasotocin and neuronal nitric oxide synthase mRNA levels in hypothalamic paraventricular nucleus and supraoptic nucleus of rat


Associated Targets

GMNN Tbio Geminin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KAT2A Tchem Histone acetyltransferase KAT2A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

POLI Tchem DNA polymerase iota 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ATM Tchem Serine-protein kinase ATM 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NOS2 Tchem Nitric oxide synthase, inducible 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NOS1 Tchem Nitric oxide synthase, brain 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NOS3 Tchem Nitric oxide synthase, endothelial 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name methyl (2S)-2-amino-5-[[amino(nitramido)methylidene]amino]pentanoate;hydrochloride
INCHI InChI=1S/C7H15N5O4.ClH/c1-16-6(13)5(8)3-2-4-10-7(9)11-12(14)15;/h5H,2-4,8H2,1H3,(H3,9,10,11);1H/t5-;/m0./s1
InChi Key QBNXAGZYLSRPJK-JEDNCBNOSA-N
Canonical SMILES COC(=O)C(CCCN=C(N)N[N+](=O)[O-])N.Cl
Isomeric SMILES COC(=O)[C@H](CCCN=C(N)N[N+](=O)[O-])N.Cl
WGK Germany 3
PubChem CID 135193
Molecular Weight 269.69
Beilstein 3744166
Reaxy-Rn 3744166

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

Specific Rotation[α]15 ° (C=3, MeOH)
Melt Point(°C)159-161°C

Safety and Hazards(GHS)

WGK Germany 3
Reaxy-Rn 3744166

Related Documents

Solution Calculators