An analog of arginine that inhibits NO production. It has multiple effects on the vascular system. Inhibits relaxation induced by acetylcholine and induces an increase in arterial blood pressure. Abolishes lecithinized superoxide dismutase induced vasodil
Storage Temp
Store at -80°C
Shipped In
Ice chest + Ice pads
Product Description
Nω-Nitro-L-arginine methyl ester hydrochloride has been used:
• to study the effects of brain-derived neurotrophic factor against neurotoxicity in rat cortical neurons
• to study its effect on far-infrared (FIR) enhanced microcirculation of rat skin
• to study its effect on leptin-induced regulation of myokine fibronectin type III domain containing five/irisin in murine myocytes and fat cells
• to study its effect on the levels of arginine Vasotocin and neuronal nitric oxide synthase mRNA levels in hypothalamic paraventricular nucleus and supraoptic nucleus of rat
2.Jiancheng Zhang, Congcong Zhang, Yuyang Li, Jingjing Xiao, Yilun Zhang, Min Jia, Lixia Lu, Hongyan Zhang, Jun Zhou, Zhenguo Zhang, Xin Du. (2023) An electrochemical sensing platform for biomonitoring the potential toxicity of plastic particles by detecting NO. CHEMICAL ENGINEERING JOURNAL, 471 (144797). [PMID:][10.1016/j.cej.2023.144797]
3.Chang Ruijing, Su Yuan, Kong Hongfang, Wang Fang, Xing Ying, Jiang Lei, Xin Hong. (2023) Upregulation of SEMP1 Contributes to Improving the Biological Functions of Trophoblast via the PI3K/AKT Pathway in Preeclampsia. MOLECULAR BIOTECHNOLOGY, (1-13). [PMID:37277581][10.1007/s12033-023-00774-3]
4.Yong Wenjing, Zhao Yanhua, Jiang Xiao’e, Li Ping. (2022) Sodium butyrate alleviates pre‐eclampsia in pregnant rats by improving the gut microbiota and short‐chain fatty acid metabolites production. JOURNAL OF APPLIED MICROBIOLOGY, 132 (2):(1370-1383). [PMID:34470077][10.1111/jam.15279]
5.Liming Wang, Shuo Huang, Tongtong Zhu, Xiaoyan Ge, Chenxi Pei, Ge Hong, Lifeng Han. (2022) Metabolomic Study on Iohexol-Induced Nephrotoxicity in Rats Based on NMR and LC–MS Analyses. CHEMICAL RESEARCH IN TOXICOLOGY, 35 (2):(244–253). [PMID:35081708][10.1021/acs.chemrestox.1c00299]
6.Huang Shuo, Tang Yanyan, Liu Tianjun, Zhang Ning, Yang Xueyan, Yang Dingwei, Hong Ge. (2020) A Novel Antioxidant Protects Against Contrast Medium-Induced Acute Kidney Injury in Rats. Frontiers in Pharmacology, 11 [PMID:33329004][10.3389/fphar.2020.599577]
7.Zhao Gao, Yu Han, Yunhui Hu, Xiaoyan Wu, Yongbin Wang, Xiaoqun Zhang, Jinjuan Fu, Xue Zou, Jun Zhang, Xiongwen Chen, Pedro A. Jose, Xi Lu, Chunyu Zeng. (2016) Targeting HO-1 by Epigallocatechin-3-Gallate Reduces Contrast-Induced Renal Injury via Anti-Oxidative Stress and Anti-Inflammation Pathways. PLoS One, 11 (2):(e0149032). [PMID:26866373][10.1371/journal.pone.0149032]
2.Jiancheng Zhang, Congcong Zhang, Yuyang Li, Jingjing Xiao, Yilun Zhang, Min Jia, Lixia Lu, Hongyan Zhang, Jun Zhou, Zhenguo Zhang, Xin Du. (2023) An electrochemical sensing platform for biomonitoring the potential toxicity of plastic particles by detecting NO. CHEMICAL ENGINEERING JOURNAL, 471 (144797). [PMID:][10.1016/j.cej.2023.144797]
3.Chang Ruijing, Su Yuan, Kong Hongfang, Wang Fang, Xing Ying, Jiang Lei, Xin Hong. (2023) Upregulation of SEMP1 Contributes to Improving the Biological Functions of Trophoblast via the PI3K/AKT Pathway in Preeclampsia. MOLECULAR BIOTECHNOLOGY, (1-13). [PMID:37277581][10.1007/s12033-023-00774-3]
4.Yong Wenjing, Zhao Yanhua, Jiang Xiao’e, Li Ping. (2022) Sodium butyrate alleviates pre‐eclampsia in pregnant rats by improving the gut microbiota and short‐chain fatty acid metabolites production. JOURNAL OF APPLIED MICROBIOLOGY, 132 (2):(1370-1383). [PMID:34470077][10.1111/jam.15279]
5.Liming Wang, Shuo Huang, Tongtong Zhu, Xiaoyan Ge, Chenxi Pei, Ge Hong, Lifeng Han. (2022) Metabolomic Study on Iohexol-Induced Nephrotoxicity in Rats Based on NMR and LC–MS Analyses. CHEMICAL RESEARCH IN TOXICOLOGY, 35 (2):(244–253). [PMID:35081708][10.1021/acs.chemrestox.1c00299]
6.Huang Shuo, Tang Yanyan, Liu Tianjun, Zhang Ning, Yang Xueyan, Yang Dingwei, Hong Ge. (2020) A Novel Antioxidant Protects Against Contrast Medium-Induced Acute Kidney Injury in Rats. Frontiers in Pharmacology, 11 [PMID:33329004][10.3389/fphar.2020.599577]
7.Zhao Gao, Yu Han, Yunhui Hu, Xiaoyan Wu, Yongbin Wang, Xiaoqun Zhang, Jinjuan Fu, Xue Zou, Jun Zhang, Xiongwen Chen, Pedro A. Jose, Xi Lu, Chunyu Zeng. (2016) Targeting HO-1 by Epigallocatechin-3-Gallate Reduces Contrast-Induced Renal Injury via Anti-Oxidative Stress and Anti-Inflammation Pathways. PLoS One, 11 (2):(e0149032). [PMID:26866373][10.1371/journal.pone.0149032]
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