Basic Description

Synonyms	Nonoxynol-2 \| 2-[2-(4-Nonylphenoxy)ethoxy]ethanol \| 2-(2-(4-Nonylphenoxy)ethoxy)ethanol \| U4A966MO25 \| DSSTox_CID_16588 \| 4-Nonylphenol diethoxylate \| 2-[2-(4-nonylphenoxy)ethoxy]-Ethanol \| CHEMBL194034 \| 2-(2-(4-nonylphenoxy)ethoxy)-Ethanol
Specifications & Purity	Proteomics grade
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	Proteomics grade
Product Description	Non ionic detergent efficiently separateshydrophilic proteins from membrane spanning, hydrophobic proteins withoutaltering biological activity. High purity and protease-free Suitable for most biological applications Non-ionic detergents have uncharged hydrophilicgroups and are gentle, non-denaturing detergents ideal for studying theconformation and function of proteins, because they keep secondary and tertiarystructure intact.

Associated Targets(Human)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)

Discover Target: TDP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AR Tclin Androgen receptor (0 Activities)

Discover Target: AR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	2-[2-(4-nonylphenoxy)ethoxy]ethanol
INCHI	InChI=1S/C19H32O3/c1-2-3-4-5-6-7-8-9-18-10-12-19(13-11-18)22-17-16-21-15-14-20/h10-13,20H,2-9,14-17H2,1H3
InChi Key	BLXVTZPGEOGTGG-UHFFFAOYSA-N
Isomeric SMILES	CCCCCCCCCC1=CC=C(C=C1)OCCOCCO
WGK Germany	2
RTECS	AX0247000
Alternate CAS	26027-38-3
PubChem CID	24773
UN Number	3082
Packing Group	III

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

22 results found

Lot Number	Certificate Type	Date	Item
K2407425	Certificate of Analysis	Oct 25, 2024	N274254
K2407424	Certificate of Analysis	Oct 25, 2024	N274254
H2409559	Certificate of Analysis	Aug 01, 2024	N274254
H2409558	Certificate of Analysis	Aug 01, 2024	N274254
H2409557	Certificate of Analysis	Aug 01, 2024	N274254
A2410030	Certificate of Analysis	Jul 05, 2023	N274254
G2322960	Certificate of Analysis	Jul 05, 2023	N274254
G2322623	Certificate of Analysis	Jul 05, 2023	N274254
G2322637	Certificate of Analysis	Jul 05, 2023	N274254
G2322951	Certificate of Analysis	Jul 05, 2023	N274254
G2322954	Certificate of Analysis	Jul 05, 2023	N274254
G2322959	Certificate of Analysis	Jul 05, 2023	N274254
B2316441	Certificate of Analysis	Feb 04, 2023	N274254
F2303011	Certificate of Analysis	Feb 04, 2023	N274254
B2316509	Certificate of Analysis	Feb 04, 2023	N274254
B2316456	Certificate of Analysis	Feb 04, 2023	N274254
L22081064	Certificate of Analysis	Nov 25, 2022	N274254
L22081066	Certificate of Analysis	Nov 25, 2022	N274254
L22081071	Certificate of Analysis	Nov 25, 2022	N274254
F2217188	Certificate of Analysis	Jun 10, 2022	N274254
F2217183	Certificate of Analysis	Jun 10, 2022	N274254
F2217182	Certificate of Analysis	Jun 10, 2022	N274254

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Chemical and Physical Properties

Flash Point(°C)	113 °C
Boil Point(°C)	290 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS09, GHS05, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H411:Toxic to aquatic life with long lasting effects H302:Harmful if swallowed H318:Causes serious eye damage H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help.
WGK Germany	2
RTECS	AX0247000
Class	9

Alternative Products

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Meiyi Zou, Yuxia Liu, Lijuan Man, Yao Lan, Qian Wei, Wanjun Jin, Qinghui Chen, Yue Jia, Xinbo Yao, Yu Lu, Linjuan Huang, Zhongfu Wang, Chengjian Wang. (2023) Comprehensive Comparison of Bioactive N-Glycans among Seven Species of Livestock and Poultry Plasma Using a Relative Quantification Strategy. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 71 (48): (19088–19100). [PMID:37972931] [10.1021/acs.jafc.3c03831]
2. Xu Ziye, Zhang Tianyu, Chen Hongyu, Zhu Yuyi, Lv Yuexiao, Zhang Shunji, Chen Jiaye, Chen Haide, Yang Lili, Jiang Weiqin, Ni Shengyu, Lu Fangru, Wang Zhaolun, Yang Hao, Dong Ling, Chen Feng, Zhang Hong, Chen Yu, Liu Jiong, Zhang Dandan, Fan Longjiang, Guo Guoji, Wang Yongcheng. (2023) High-throughput single nucleus total RNA sequencing of formalin-fixed paraffin-embedded tissues by snRandom-seq. Nature Communications, 14 (1): (1-12). [PMID:37173341] [10.1038/s41467-023-38409-5]
3. Chengjian Wang, Xi Gao, Guiping Gong, Lijuan Man, Qian Wei, Yao Lan, Meifang Yang, Jianli Han, Wanjun Jin, Ming Wei, Linjuan Huang, Zhongfu Wang. (2022) A versatile strategy for high-resolution separation of reducing glycan mixtures as hydrazones by two-dimensional high-performance liquid chromatography. JOURNAL OF CHROMATOGRAPHY A, 1685 (463599). [PMID:36345072] [10.1016/j.chroma.2022.463599]
4. Lancheng Wang, Mingjie Xu, Huimin Zhou, Kun Yan, Shiqi Duan, Dandan Xue, Youmei Wang, Bin Di, Chi Hu. (2022) Teaching PCR for Simultaneous Sensing of Gene Transcription and Downstream Metabolites by Cucurbit[8]uril-Mediated Intervention of Polymerase Activity. ANALYTICAL CHEMISTRY, 94 (24): (8715–8723). [PMID:35671188] [10.1021/acs.analchem.2c01103]
5. Peizhong Gao, Hang Yao, Shoujun Yuan, Yulan Wang, Wei Wang, Ibrahim Mohamed Ali, Zhen-Hu Hu. (2021) Degradation of Nonylphenol Ethoxylate-40 in High Saline Wastewater by Electrochemical Oxidation. ENVIRONMENTAL ENGINEERING SCIENCE, 38 (2): (81-88). [PMID:] [10.1089/ees.2020.0045]
6. Dan Wang, Jiangfei Lou, Jiugang Yuan, Jin Xu, Ruofei Zhu, Qiang Wang, Xuerong Fan. (2021) Laccase immobilization on core-shell magnetic metal-organic framework microspheres for alkylphenol ethoxylate compound removal. Journal of Environmental Chemical Engineering, 9 (105000). [PMID:] [10.1016/j.jece.2020.105000]
7. Haiyang Zhang, Yuanyuan Deng, Xinyi Liu, Jie Sun, Leyao Ma, Yajie Ding, Zhen Zhan, Hao Zhang, Yuchen Yang, Yanhong Gu, Anton B. Iliuk, Chenxi Yang, W. Andy Tao. (2020) Glass Fiber-Supported Hybrid Monolithic Spin Tip for Enrichment of Phosphopeptides from Urinary Extracellular Vesicles. ANALYTICAL CHEMISTRY, 92 (21): (14790–14797). [PMID:33074658] [10.1021/acs.analchem.0c03557]
8. Xuexia Zhu, Zeshuang Wang, Yunfei Sun, Lei Gu, Lu Zhang, Jun Wang, Yuan Huang, Zhou Yang. (2020) Surfactants at environmentally relevant concentrations interfere the inducible defense of Scenedesmus obliquus and the implications for ecological risk assessment. ENVIRONMENTAL POLLUTION, 261 (114131). [PMID:32066053] [10.1016/j.envpol.2020.114131]
9. Jian-Li HAN, Qing-Hui CHEN, Mei-Yi ZOU, Yu LU, Ming WEI, Cheng LI, Cheng-Jian WANG, Lin-Juan HUANG, Zhong-Fu WANG. (2020) Separation and Purification of Sialylglycopeptide from Egg Yolk Based on Cotton Hydrophilic Chromatography. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 48 (34). [PMID:] [10.1016/S1872-2040(19)61209-0]
10. Zilei Zhang, Danlei Liu, Qingping Wu, Yu Lu, Peng Tian, Zhongfu Wang, Dapeng Wang. (2020) Characterization of a Histo-Blood Group Antigen-like Substance in Romaine Lettuce That Contributes to Human Norovirus Attachment. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 68 (5): (1207–1212). [PMID:31755264] [10.1021/acs.jafc.9b05887]
11. Bin Zhang, Yujie Jiang. (2019) QGO enhanced PET fibre for multi-applications. Micro & Nano Letters, 14 (3): (224-229). [PMID:] [10.1049/mnl.2018.5105]
12. Bin Zhang, Yujie Jiang. (2018) Durable antibacterial and hydrophobic polyester fibres and wearable textiles. Micro & Nano Letters, 13 (7): (1011-1016). [PMID:] [10.1049/mnl.2018.0197]
13. Naling Bai, Sheng Wang, Pengfei Sun, Rexiding Abuduaini, Xufen Zhu, Yuhua Zhao. (2018) Degradation of nonylphenol polyethoxylates by functionalized Fe3O4 nanoparticle-immobilized Sphingomonas sp. Y2. SCIENCE OF THE TOTAL ENVIRONMENT, 615 (462). [PMID:28988082] [10.1016/j.scitotenv.2017.09.290]
14. Lingmei Li, Chengjian Wang, Shan Qiang, Jixiang Zhao, Shuang Song, Wanjun Jin, Bo Wang, Ying Zhang, Linjuan Huang, Zhongfu Wang. (2016) Mass Spectrometric Analysis of N-Glycoforms of Soybean Allergenic Glycoproteins Separated by SDS-PAGE. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 64 (39): (7367–7376). [PMID:27616296] [10.1021/acs.jafc.6b02773]
15. Chengjian Wang, Zhiyu Wu, Jiangbei Yuan, Bo Wang, Ping Zhang, Ying Zhang, Zhongfu Wang, Linjuan Huang. (2014) Simplified Quantitative Glycomics Using the Stable Isotope Label Girard’s Reagent P by Electrospray Ionization Mass Spectrometry. JOURNAL OF PROTEOME RESEARCH, 13 (2): (372–384). [PMID:24274809] [10.1021/pr4010647]
16. Chengjian Wang, Jiangbei Yuan, Xiaohua Li, Zhongfu Wang, Linjuan Huang. (2013) Sulfonyl hydrazine-functionalized polymer as a specific capturer of reducing glycans from complex samples for high-throughput analysis by electrospray ionization mass spectrometry. ANALYST, 138 (18): (5344-5356). [PMID:23875183] [10.1039/C3AN00931A]

References

1. Meiyi Zou, Yuxia Liu, Lijuan Man, Yao Lan, Qian Wei, Wanjun Jin, Qinghui Chen, Yue Jia, Xinbo Yao, Yu Lu, Linjuan Huang, Zhongfu Wang, Chengjian Wang. (2023) Comprehensive Comparison of Bioactive N-Glycans among Seven Species of Livestock and Poultry Plasma Using a Relative Quantification Strategy. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 71 (48): (19088–19100). [PMID:37972931] [10.1021/acs.jafc.3c03831]
2. Xu Ziye, Zhang Tianyu, Chen Hongyu, Zhu Yuyi, Lv Yuexiao, Zhang Shunji, Chen Jiaye, Chen Haide, Yang Lili, Jiang Weiqin, Ni Shengyu, Lu Fangru, Wang Zhaolun, Yang Hao, Dong Ling, Chen Feng, Zhang Hong, Chen Yu, Liu Jiong, Zhang Dandan, Fan Longjiang, Guo Guoji, Wang Yongcheng. (2023) High-throughput single nucleus total RNA sequencing of formalin-fixed paraffin-embedded tissues by snRandom-seq. Nature Communications, 14 (1): (1-12). [PMID:37173341] [10.1038/s41467-023-38409-5]
3. Chengjian Wang, Xi Gao, Guiping Gong, Lijuan Man, Qian Wei, Yao Lan, Meifang Yang, Jianli Han, Wanjun Jin, Ming Wei, Linjuan Huang, Zhongfu Wang. (2022) A versatile strategy for high-resolution separation of reducing glycan mixtures as hydrazones by two-dimensional high-performance liquid chromatography. JOURNAL OF CHROMATOGRAPHY A, 1685 (463599). [PMID:36345072] [10.1016/j.chroma.2022.463599]
4. Lancheng Wang, Mingjie Xu, Huimin Zhou, Kun Yan, Shiqi Duan, Dandan Xue, Youmei Wang, Bin Di, Chi Hu. (2022) Teaching PCR for Simultaneous Sensing of Gene Transcription and Downstream Metabolites by Cucurbit[8]uril-Mediated Intervention of Polymerase Activity. ANALYTICAL CHEMISTRY, 94 (24): (8715–8723). [PMID:35671188] [10.1021/acs.analchem.2c01103]
5. Peizhong Gao, Hang Yao, Shoujun Yuan, Yulan Wang, Wei Wang, Ibrahim Mohamed Ali, Zhen-Hu Hu. (2021) Degradation of Nonylphenol Ethoxylate-40 in High Saline Wastewater by Electrochemical Oxidation. ENVIRONMENTAL ENGINEERING SCIENCE, 38 (2): (81-88). [PMID:] [10.1089/ees.2020.0045]
6. Dan Wang, Jiangfei Lou, Jiugang Yuan, Jin Xu, Ruofei Zhu, Qiang Wang, Xuerong Fan. (2021) Laccase immobilization on core-shell magnetic metal-organic framework microspheres for alkylphenol ethoxylate compound removal. Journal of Environmental Chemical Engineering, 9 (105000). [PMID:] [10.1016/j.jece.2020.105000]
7. Haiyang Zhang, Yuanyuan Deng, Xinyi Liu, Jie Sun, Leyao Ma, Yajie Ding, Zhen Zhan, Hao Zhang, Yuchen Yang, Yanhong Gu, Anton B. Iliuk, Chenxi Yang, W. Andy Tao. (2020) Glass Fiber-Supported Hybrid Monolithic Spin Tip for Enrichment of Phosphopeptides from Urinary Extracellular Vesicles. ANALYTICAL CHEMISTRY, 92 (21): (14790–14797). [PMID:33074658] [10.1021/acs.analchem.0c03557]
8. Xuexia Zhu, Zeshuang Wang, Yunfei Sun, Lei Gu, Lu Zhang, Jun Wang, Yuan Huang, Zhou Yang. (2020) Surfactants at environmentally relevant concentrations interfere the inducible defense of Scenedesmus obliquus and the implications for ecological risk assessment. ENVIRONMENTAL POLLUTION, 261 (114131). [PMID:32066053] [10.1016/j.envpol.2020.114131]
9. Jian-Li HAN, Qing-Hui CHEN, Mei-Yi ZOU, Yu LU, Ming WEI, Cheng LI, Cheng-Jian WANG, Lin-Juan HUANG, Zhong-Fu WANG. (2020) Separation and Purification of Sialylglycopeptide from Egg Yolk Based on Cotton Hydrophilic Chromatography. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 48 (34). [PMID:] [10.1016/S1872-2040(19)61209-0]
10. Zilei Zhang, Danlei Liu, Qingping Wu, Yu Lu, Peng Tian, Zhongfu Wang, Dapeng Wang. (2020) Characterization of a Histo-Blood Group Antigen-like Substance in Romaine Lettuce That Contributes to Human Norovirus Attachment. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 68 (5): (1207–1212). [PMID:31755264] [10.1021/acs.jafc.9b05887]
11. Bin Zhang, Yujie Jiang. (2019) QGO enhanced PET fibre for multi-applications. Micro & Nano Letters, 14 (3): (224-229). [PMID:] [10.1049/mnl.2018.5105]
12. Bin Zhang, Yujie Jiang. (2018) Durable antibacterial and hydrophobic polyester fibres and wearable textiles. Micro & Nano Letters, 13 (7): (1011-1016). [PMID:] [10.1049/mnl.2018.0197]
13. Naling Bai, Sheng Wang, Pengfei Sun, Rexiding Abuduaini, Xufen Zhu, Yuhua Zhao. (2018) Degradation of nonylphenol polyethoxylates by functionalized Fe3O4 nanoparticle-immobilized Sphingomonas sp. Y2. SCIENCE OF THE TOTAL ENVIRONMENT, 615 (462). [PMID:28988082] [10.1016/j.scitotenv.2017.09.290]
14. Lingmei Li, Chengjian Wang, Shan Qiang, Jixiang Zhao, Shuang Song, Wanjun Jin, Bo Wang, Ying Zhang, Linjuan Huang, Zhongfu Wang. (2016) Mass Spectrometric Analysis of N-Glycoforms of Soybean Allergenic Glycoproteins Separated by SDS-PAGE. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 64 (39): (7367–7376). [PMID:27616296] [10.1021/acs.jafc.6b02773]
15. Chengjian Wang, Zhiyu Wu, Jiangbei Yuan, Bo Wang, Ping Zhang, Ying Zhang, Zhongfu Wang, Linjuan Huang. (2014) Simplified Quantitative Glycomics Using the Stable Isotope Label Girard’s Reagent P by Electrospray Ionization Mass Spectrometry. JOURNAL OF PROTEOME RESEARCH, 13 (2): (372–384). [PMID:24274809] [10.1021/pr4010647]
16. Chengjian Wang, Jiangbei Yuan, Xiaohua Li, Zhongfu Wang, Linjuan Huang. (2013) Sulfonyl hydrazine-functionalized polymer as a specific capturer of reducing glycans from complex samples for high-throughput analysis by electrospray ionization mass spectrometry. ANALYST, 138 (18): (5344-5356). [PMID:23875183] [10.1039/C3AN00931A]

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SKU	Size	Availability	Price
N274254-50ml	50ml	In stock	$63.90
N274254-100ml	100ml	In stock	$94.90
N274254-500ml	500ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$301.90

Nonidet P 40 Substitute - Proteomics Grade, high purity , CAS No.9016-45-9