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Noradrenaline bitartrate monohydrate - ≥98%(HPLC),USP, high purity , CAS No.108341-18-0

  • PharmPure™
  • USP
  • ≥98%(HPLC)
Item Number
N107258
Grouped product items
SKUSizeAvailabilityPrice Qty
N107258-200mg
200mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$60.90
N107258-250mg
250mg
In stock
$65.90
N107258-1g
1g
In stock
$216.90
N107258-5g
5g
In stock
$640.90
N107258-25g
25g
In stock
$2,884.90

Endogenous α adrenoceptor agonist

Basic Description

Synonyms108341-18-0|L-Noradrenaline bitartrate monohydrate|Noradrenaline bitartrate monohydrate|Binodrenal|IFY5PE3ZRW|Arterenol, tartrate, monohydrate|Norepinephrine bitartrate monohydrate|Levarterenol bitartrate monohydrate|69815-49-2|Norepinephrine (bitartrate
Specifications & PurityPharmPure™, USP, ≥98%(HPLC)
Biochemical and Physiological MechanismsL-Noradrenaline Bitartrate Monohydrate is a demethylated precursor of epinephrine (adrenaline). It is a sympathomimetic hormone produced by the adrenal gland.Autonomic nervous system neurotransmitter released by sympathetic nerve terminals.
Storage TempStore at 2-8°C
Shipped InWet ice
GradePharmPure™, USP
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Noradrenaline bitartrate monohydrate is a direct alpha-adrenergic receptors stimulator.
A demethylated precursor of epinephrine.

Associated Targets

CX3CR1 Tchem CX3C chemokine receptor 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GPR35 Tchem G-protein coupled receptor 35 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

BRD4 Tchem Bromodomain-containing protein 4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CDK2 Tchem Cyclin-dependent kinase 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

FFAR4 Tchem Free fatty acid receptor 4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

FPR2 Tchem N-formyl peptide receptor 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

FGFR3 Tclin Fibroblast growth factor receptor 3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CSNK1D Tchem Casein kinase I isoform delta 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

S1PR1 Tclin Sphingosine 1-phosphate receptor 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC6A2 Tclin Sodium-dependent noradrenaline transporter 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TRIM24 Tchem Transcription intermediary factor 1-alpha 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

C5AR1 Tclin C5a anaphylatoxin chemotactic receptor 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

BRPF1 Tchem Peregrin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AURKA Tchem Aurora kinase A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRB2 Tclin Beta-2 adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

APLNR Tchem Apelin receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABL1 Tclin Tyrosine-protein kinase ABL1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA2A Tclin Alpha-2A adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADGRF1 Tbio Adhesion G-protein coupled receptor F1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AGTR1 Tclin Type-1 angiotensin II receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GSK3B Tclin Glycogen synthase kinase-3 beta 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GPR119 Tclin Glucose-dependent insulinotropic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GLP1R Tclin Glucagon-like peptide 1 receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAPK1 Tchem Mitogen-activated protein kinase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol;(2R,3R)-2,3-dihydroxybutanedioic acid;hydrate
INCHI InChI=1S/C8H11NO3.C4H6O6.H2O/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10;/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10);1H2/t8-;1-,2-;/m01./s1
InChi Key LNBCGLZYLJMGKP-LUDZCAPTSA-N
Canonical SMILES C1=CC(=C(C=C1C(CN)O)O)O.C(C(C(=O)O)O)(C(=O)O)O.O
Isomeric SMILES C1=CC(=C(C=C1[C@H](CN)O)O)O.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O.O
WGK Germany 3
RTECS DN6750000
Alternate CAS 51-40-1
PubChem CID 3047796
Molecular Weight 337.28
Beilstein 4078502

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

9 results found

Lot NumberCertificate TypeDateItem
J2312161Certificate of AnalysisOct 19, 2023 N107258
J2312519Certificate of AnalysisOct 19, 2023 N107258
F2305664Certificate of AnalysisApr 27, 2023 N107258
F2305665Certificate of AnalysisApr 27, 2023 N107258
F2305667Certificate of AnalysisApr 27, 2023 N107258
F2305673Certificate of AnalysisApr 27, 2023 N107258
F2305674Certificate of AnalysisApr 27, 2023 N107258
D2324765Certificate of AnalysisMar 23, 2023 N107258
D2324794Certificate of AnalysisMar 23, 2023 N107258

Chemical and Physical Properties

SolubilityDMSO 64 mg/mL;Water 64 mg/mL;Ethanol <1 mg/mL
SensitivityLight sensitive.
Specific Rotation[α]-10.0 to -12.0 deg(C=5, H2O)
Melt Point(°C)129 °C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

Precautionary Statements

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P301+P317:IF SWALLOWED: Get medical help.

WGK Germany 3
RTECS DN6750000

Related Documents

References

1. Yang B et al..  (2021)  Locus coeruleus anchors a trisynaptic circuit controlling fear-induced suppression of feeding..  Neuron,  109  (5): (823-838.e6).  [PMID:33476548]
2. Gao XJ et al..  (2020)  Multi-in-One: Multiple-proteases, One-hour-shot Strategy for Fast and High-coverage Phosphoproteomic Investigation..  Anal Chem,      [PMID:32479063]
3. Honda K et al..  (2021)  On-tissue polysulfide visualization by surface-enhanced Raman spectroscopy benefits patients with ovarian cancer to predict post-operative chemosensitivity..  Redox Biol,  41  (101926).  [PMID:33752108]
4. Rajalingam D et al..  (2021)  Workplace bullying increases the risk of anxiety through a stress-induced ß2-adrenergic receptor mechanism: a multisource study employing an animal model, cell culture experiments and human data..  Int Arch Occup Environ Health,  94  (8): (1905-1915).  [PMID:34076732]

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