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Nordihydroguaiaretic Acid - ≥95%, high purity , CAS No.500-38-9

Moligand™
≥95%

CAS#: 500-38-9
Formula: C₁₈H₂₂O₄
Molecular Weight: 302.37
Beilstein Registry Number: 6(1)577
MDL number: MFCD00002206
PubChem CID: 4534

Item Number

N133726

Grouped product items
SKU	Size	Availability	Price
N133726-250mg	250mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$117.90
N133726-1g	1g	In stock	$424.90
N133726-5g	5g	In stock	$1,911.90

Naturally occurring potent antioxidant

View related series

VRAC Channel blocker

Basic Description

Synonyms	NORDIHYDROGUAIARETIC ACID\|500-38-9\|NDGA\|Dihydronorguaiaretic acid\|Actinex\|4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol\|Norhydroguaiaretic acid\|Norguaiaretic acid, dihydro-\|1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-\|Dinorguaia
Specifications & Purity	Moligand™, ≥95%
Biochemical and Physiological Mechanisms	Lipoxygenase inhibitor; polyphenol-bearing o-dihydroxy (catechol) structure.Naturally occurring potent antioxidant. Various pharmacological effects in vitro and in vivo . Anticancer, antimicrobial, anti-inflammatory and immunosuppressive activities.
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice
Grade	Moligand™
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Product Introduction Nordihydroguaiaretic acid (NDGA) is used as an antioxidant and potent scavenger of reactive oxygen species (ROS) Application Nordihydroguaiaretic acid can be used: In the synthesis of nordihydroguaiaretic acid derivatives with potent HIV inhibition activity；As a starting material in the synthesis of tetra-O-methylnordihydroguaiaretic acid.

Names and Identifiers

IUPAC Name	4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
INCHI	InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3
InChi Key	HCZKYJDFEPMADG-UHFFFAOYSA-N
Canonical SMILES	CC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O
Isomeric SMILES	CC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O
WGK Germany	3
RTECS	UX1750000
PubChem CID	4534
Molecular Weight	302.37
Beilstein	6(1)577
Reaxy-Rn	9803564

Database links

DrugBank Ligand	DB00179
Wikipedia	Nordihydroguaiaretic_acid, Masoprocol
CAS Registry No.	500-38-9
PubChem CID	4534
ChEMBL Ligand	CHEMBL52

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

8 results found

Lot Number	Certificate Type	Date	Item
K2216303	Certificate of Analysis	Aug 14, 2024	N133726
F2130264	Certificate of Analysis	Apr 14, 2023	N133726
C2303208	Certificate of Analysis	Mar 14, 2023	N133726
F2225282	Certificate of Analysis	Jun 02, 2022	N133726
F2225283	Certificate of Analysis	Jun 02, 2022	N133726
F2225407	Certificate of Analysis	Jun 02, 2022	N133726
G2410138	Certificate of Analysis	Jun 02, 2022	N133726
K2316078	Certificate of Analysis	Jun 02, 2022	N133726

Chemical and Physical Properties

Solubility	Soluble in 100% ethanol, methanol, acetone, dimethylsulfoxide, dimethylformamide, ethanol (5% w/v), glycol, PEG, and slightly soluble in hot water. Insoluble in water.
Sensitivity	Air sensitive
Melt Point(°C)	184-188℃

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	UX1750000
Reaxy-Rn	9803564
Merck Index	6693

Alternative Products

References

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