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Nordihydroguaiaretic Acid - 10mM in DMSO, high purity , CAS No.500-38-9
Naturally occurring potent antioxidant
Basic Description Synonyms NORDIHYDROGUAIARETIC ACID|500-38-9|NDGA|Dihydronorguaiaretic acid|Actinex|4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol|Norhydroguaiaretic acid|Norguaiaretic acid, dihydro-|1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-|Dinorguaia Specifications & Purity Moligand™, 10mM in DMSO Biochemical and Physiological Mechanisms Lipoxygenase inhibitor; polyphenol-bearing o-dihydroxy (catechol) structure.Naturally occurring potent antioxidant. Various pharmacological effects in vitro and in vivo . Anticancer, antimicrobial, anti-inflammatory and immunosuppressive activities. Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Grade Moligand™ Product Description Product Introduction
Nordihydroguaiaretic acid (NDGA) is used as an antioxidant and potent scavenger of reactive oxygen species (ROS)
Application
Nordihydroguaiaretic acid can be used:
In the synthesis of nordihydroguaiaretic acid derivatives with potent HIV inhibition activity;As a starting material in the synthesis of tetra-O-methylnordihydroguaiaretic acid.
Names and Identifiers IUPAC Name 4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol INCHI InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3 InChi Key HCZKYJDFEPMADG-UHFFFAOYSA-N Canonical SMILES CC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O Isomeric SMILES CC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O WGK Germany 3 RTECS UX1750000 PubChem CID 4534 Molecular Weight 302.37 Beilstein 6(1)577 Reaxy-Rn 9803564
Chemical and Physical Properties Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
H302: Harmful if swallowed
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P270: Do not eat, drink or smoke when using this product.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P362+P364: Take off contaminated clothing and wash it before reuse.
P330: Rinse mouth.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P301+P317: IF SWALLOWED: Get medical help.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
P319: Get medical help if you feel unwell.
WGK Germany 3 RTECS UX1750000 Reaxy-Rn 9803564 Merck Index 6693
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