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Nortriptyline Hydrochloride - ≥98% (HPLC), high purity , Norepinephrine transporter inhibitor, CAS No.894-71-3, Norepinephrine transporter inhibitor

≥98%(HPLC)

CAS#: 894-71-3
Formula: C₁₉H₂₁N · HCl
Molecular Weight: 299.84
EC Number: 212-973-0
MDL number: MFCD00058024
PubChem CID: 441358

Item Number

N136755

Grouped product items
SKU	Size	Availability	Price	Qty
N136755-1g	1g	In stock	$9.90
N136755-5g	5g	In stock	$34.90

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Pharmaceutical ingredients Seven membered ring compound

Basic Description

Synonyms	Nortriptyline hydrochloride\|894-71-3\|Nortriptyline Hcl\|Pamelor\|Acetexa\|Altilev\|Desmethylamitriptyline hydrochloride\|Allegron\|Sensival\|Vividyl\|Aventyl hydrochloride\|Aventyl allegron\|Nortriptyline (hydrochloride)\|Ateben hydrochloride\|Nortab hydrochloride\|No
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter (Ki = 3.4 nM) than the serotonin transporter (Ki = 161 nM). 5-HT2 serotonin receptor antagonist.
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads
Action Type	INHIBITOR
Mechanism of action	Norepinephrine transporter inhibitor

Associated Targets

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

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EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 0 Activities

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GMNN Tbio Geminin 0 Activities

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FTL Tbio Ferritin light chain 0 Activities

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KMT2A Tchem Histone-lysine N-methyltransferase 2A 0 Activities

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SMN1 Tchem Survival motor neuron protein 0 Activities

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SLC6A2 Tclin Sodium-dependent noradrenaline transporter 0 Activities

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SMAD3 Tchem Mothers against decapentaplegic homolog 3 0 Activities

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PMP22 Tbio Peripheral myelin protein 22 0 Activities

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LMNA Tbio Prelamin-A/C 0 Activities

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ALOX15B Tchem Arachidonate 15-lipoxygenase B 0 Activities

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MPHOSPH8 Tbio M-phase phosphoprotein 8 0 Activities

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

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MAPT Tclin Microtubule-associated protein tau 0 Activities

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KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities

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KPNB1 Tbio Importin subunit beta-1 0 Activities

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GLP1R Tclin Glucagon-like peptide 1 receptor 0 Activities

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IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic 0 Activities

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NPSR1 Tchem Neuropeptide S receptor 0 Activities

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Names and Identifiers

IUPAC Name	N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine;hydrochloride
INCHI	InChI=1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-11,20H,6,12-14H2,1H3;1H
InChi Key	SHAYBENGXDALFF-UHFFFAOYSA-N
Canonical SMILES	CNCCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl
Isomeric SMILES	CNCCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl
WGK Germany	3
RTECS	HP0175000
PubChem CID	441358
Molecular Weight	299.84
Reaxy-Rn	4163872

Certificates

Certificate of Analysis(COA)

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2 results found

Lot Number	Certificate Type	Date	Item
K2103330	Certificate of Analysis	Aug 04, 2023	N136755
K2103332	Certificate of Analysis	Aug 04, 2023	N136755

Solubility

ethanol: 100 mg/mL H2O: soluble

Sensitivity

Sensitive to light

Melt Point(°C)

218 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed
Precautionary Statements	P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help.
WGK Germany	3
RTECS	HP0175000
Reaxy-Rn	4163872
Merck Index	6715

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